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Cyclosporin A 59865-13-3

4 Inquiries

Unit Price: Get Latest Price
CAS No.:

59865-13-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

Flying

Packaging:

10g/1kg/ 10kg/ 25kg

Sample Available:

Yes

Price valid (until):

2026-05-02

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
Average Lead Time:
25 days
Qualification:
Main Products:

vitamin

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Superiority

    1.High quality and competitive price.
    2.Free sample for your evaluation.
    3.Promptly delivery by well-reputed shipping lines.
    4.Trial order is available for testing after samples.
    5.We will inform you all the information at every stage in advance.
    6.Packaging can gear to buyers’ special request. 

    Our service

    1. Reply your inquiry in 24 working hours.
    2. Customized design is available. OEM are welcomed.
    3. Exclusive and unique solution can be provided to our customer by our well-trained and professional engineers and
    staff.
    4. Professional factory: We are manufacturer, specializing in producing all kinds of herb extract for more than 10 years, competitive with good quantity.
    5. As an honest seller, we always use superior raw material, advanced machines, skilled technicians to ensure our products to be finished in high quality and stable feature.


    Hainan Flying International Trade Co., Ltd., was established in 2020, It is a professional supplier of Human APIs, Veterinary, Food Additives, Vitamins, Chemicals, Plant Extract and natural active ingredients. It has absolute advantage because of strong research strength, modern management system and high-quality marketing team.

    For customer’s needs, OEM service is also acceptable. If you have a good idea in new product production but lack of laboratory device and human resource, we are glad to solve this problem for you. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.

    .






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    RAQ





    Q1: How to confirm the Product Quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirement for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What's your MOQ ?
    A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
    Q: Is there a discount ?
    A: Yes, for larger quantity, we always support with better price.

    Q5: How to start orders or make payments ?
    A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.


    ECHEMI Editorial Reference
    Cyclosporin A is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM.
    Cyclosporin a appears as white prismatic needles (from acetone) or white powder. (NTP, 1992)
    Cyclosporin a appears as white prismatic needles (from acetone) or white powder. (NTP, 1992)|Cyclosporine is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after solid organ transplantation. Cyclosporine therapy can be associated with mild elevations in serum bilirubin and transient serum enzyme elevations, and to rare instances of clinically apparent cholestatic liver injury.|Voclosporin is an orally available calcineurin inhibitor and potent immunosuppressive agent which is used in combination with mycophenolate mofetil and corticosteroids to treat acute lupus nephritis. Voclosporin may be associated with low rate of transient serum enzyme elevations during treatment but has not been linked to instances of clinically apparent acute liver injury with jaundice.|A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).

    Basic Info
    Product Name:

    Cyclosporin A

    Other Name:

    ol27-400;s7481f1;sandimmun;sandimmune;ANTIBIOTIC S 7481F1;ANTIBIOTIC S 7481FI;CICLOSPORIN;CICLOSPORIN A

    CAS No.:

    59865-13-3

    Molecular Formula:

    C62H111N11O12

    InChIKeys:

    PMATZTZNYRCHOR-UHFFFAOYSA-N

    Molecular Weight:

    1202.61

    Exact Mass:

    1201.841309

    EC Number:

    200-835-2

    DSSTox ID:

    DTXSID0020365

    Color/Form:

    Forms white prismatic crystals from acetone

    HScode:

    2941909000

    Characteristics
    PSA:

    279 Ų

    XLogP3:

    2.92 (LogP)

    Appearance:

    white solid

    Density:

    1.0±0.1 g/cm3

    Melting Point:

    148-151°C

    Boiling Point:

    1293.8°C at 760 mmHg

    Flash Point:

    87℃

    Refractive Index:

    1.468

    Water Solubility:

    soluble in dimethyl sulfoxide and ethanol. Insoluble in water.ethanol: 30 mg/mL

    Storage Conditions:

    2-8°C

    Toxicity:

    LD50 in mice, rats, rabbits (mg/kg): 107, 25, >10 i.v.; 2329, 1480, >1000 orally (Ryffel)

    Specific rotation:

    D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methanol)

    Air and Water Reactions:

    Slightly water soluble (NTP, 1992).

    Reactive Group:

    Amides and Imides

    Reactivity Profile:

    CYCLOSPORIN A is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Carcinogenicity, Category 1B

    Reproductive toxicity, Category 1B

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H302 Harmful if swallowed

    H350 May cause cancer

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    vitamin

    Location:

    Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment

    Average lead Time:

    25 days

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    Less than 5

    Year of Establishment:

    2023

    Corporate Statement

    Dear Valued Clients and Partners,

    Hello! Since the internal personnel adjustment at our company in early August this year, we have detected on the ECHEMI platform and other foreign trade channels that fraudsters have been impersonating our staff to proactively contact clients, discussing orders and promoting products under our company name, in an attempt to induce clients to make offline transfers and commit fraud.

    We hereby solemnly remind you: For all new and existing clients who have been in contact with us since early August, please remain vigilant, carefully verify the identity of the personnel you are dealing with, guard against fraud, and never make payments to unknown accounts!

    Our only official business communication channels: We conduct business discussions, quotations, and order coordination exclusively via WhatsApp and Alibaba enterprise email. We do not use other unfamiliar social media apps, personal WeChat accounts, or non-Alibaba email addresses for formal business cooperation. Below is the official list of our current sales personnel. All external contact personnel information is subject to this notice:

    Account Name

    Account (WhatsApp)

    Email

    Lucy

    +86 188****0700

    sales1@hnflying.com

    Ali

    +86 183****3262

    sales2@hnflying.com

    Sage

    +86 183****3411

    sales3@hnflying.com

    Alice

    +86 131****0556

    sales4@hnflying.com

    Faye

    +86 188****3201

    sales5@hnflying.com

    Betty

    +86 177****6677

    sales6@hnflying.com

    Seraphina

    +852 98592118

    sales6@hnflying.com

    Nancy

    +86 185****1119

    sales7@hnflying.com

    Lee

    +86 182****9198

    sales8@hnflying.com

    Lee

    +852 64646943

    sales8@hnflying.com

    Scott's Little Shop

    +86 136****4662

    sales9@hnflying.com

    Hainan Flying

    +852 47372605

    sales9@hnflying.com

    Thomas

    +852 70865163

    sales10@hnflying.com

    Thomas

    +86 151****6521

    sales10@hnflying.com

    Tammy

    +86 151****7485

    sales11@hnflying.com

    Tammy

    +852 92264509

    sales11@hnflying.com

    Steve

    +86 138****9115

    sales12@hnflying.com

    Clara Winter

    +852 95409703

    sales12@hnflying.com

    Rayna

    +852 91703396

    sales13@hnflying.com

     

    Verification Notice: If you encounter someone claiming to be our employee whose name, WhatsApp account, or Alibaba email does not match the list above, or if they guide you to transact outside official channels, urge urgent payment, or temporarily change the receiving account, please immediately stop communication and submit all contact information and chat records to us. We will simultaneously preserve evidence, report to the platform, and if necessary, hand the matter over to public security authorities.

    Disclaimer: Any person not listed above as current staff, not using our official Alibaba email address, and not using our official WhatsApp account — all business discussions, product quotations, order signings, and payment transactions conducted in our name are completely unrelated to our company. We assume no responsibility for any financial losses, contract disputes, or legal risks arising therefrom.

    If you have any doubts about the identity of the personnel you are dealing with, please feel free to verify with us at any time through the official contact information listed in this notice!

     

    Hainan Zhanyi International Trade Co., Ltd.

  • Inquiry History
    4 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    CYCLOSPORINE

    1 KG Dec 26, 2025
    United States

    Cyclosporine A

    100 G Aug 21, 2025
    Pakistan

    CICLOSPORIN

    1 KG Sep 30, 2024
    India

    Cyclosporine

    1.00 KG Dec 22, 2023
    Post an enquiry for this product
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