Cyclosporine
5 Inquiries
59865-13-3
Pharma Grade
99%
DAHAI BIOCHEM
25kg/Cardboard Drum
2026-12-31
HARD FAT
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceCyclosporin A is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM.
Cyclosporin a appears as white prismatic needles (from acetone) or white powder. (NTP, 1992)
Cyclosporin a appears as white prismatic needles (from acetone) or white powder. (NTP, 1992)|Cyclosporine is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after solid organ transplantation. Cyclosporine therapy can be associated with mild elevations in serum bilirubin and transient serum enzyme elevations, and to rare instances of clinically apparent cholestatic liver injury.|Voclosporin is an orally available calcineurin inhibitor and potent immunosuppressive agent which is used in combination with mycophenolate mofetil and corticosteroids to treat acute lupus nephritis. Voclosporin may be associated with low rate of transient serum enzyme elevations during treatment but has not been linked to instances of clinically apparent acute liver injury with jaundice.|A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).Basic Info-
Product Name:
Cyclosporin A
Other Name:ol27-400;s7481f1;sandimmun;sandimmune;ANTIBIOTIC S 7481F1;ANTIBIOTIC S 7481FI;CICLOSPORIN;CICLOSPORIN A
CAS No.:59865-13-3
Molecular Formula:C62H111N11O12
InChIKeys:PMATZTZNYRCHOR-UHFFFAOYSA-N
Molecular Weight:1202.61
Exact Mass:1201.841309
EC Number:200-835-2
DSSTox ID:DTXSID0020365
Color/Form:Forms white prismatic crystals from acetone
HScode:2941909000
Categories:
Characteristics-
PSA:
279 Ų
XLogP3:2.92 (LogP)
Appearance:white solid
Density:1.0±0.1 g/cm3
Melting Point:148-151°C
Boiling Point:1293.8°C at 760 mmHg
Flash Point:87℃
Refractive Index:1.468
Water Solubility:soluble in dimethyl sulfoxide and ethanol. Insoluble in water.ethanol: 30 mg/mL
Storage Conditions:2-8°C
Toxicity:LD50 in mice, rats, rabbits (mg/kg): 107, 25, >10 i.v.; 2329, 1480, >1000 orally (Ryffel)
Specific rotation:D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methanol)
Air and Water Reactions:Slightly water soluble (NTP, 1992).
Reactive Group:Amides and Imides
Reactivity Profile:CYCLOSPORIN A is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Carcinogenicity, Category 1B
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H302 Harmful if swallowed
H350 May cause cancer
H360 May damage fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
HARD FAT
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Location:
BUILDING 4,NO.571, STR.19,BAIYANG DISTRICT, HANGZHOU,CHINA
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
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Total Annual Revenue:
Less than $1 million
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Total Employees:
5-10
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Year of Establishment:
2025
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Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
CYCLOSPORINE
1 KG Dec 26, 2025
Pakistan
Cyclosporine
8 KG Sep 5, 2024 
India
Cyclosporine
1.00 KG Dec 22, 2023 
United States
Cyclosporine A
100 G Aug 21, 2025
Pakistan
CICLOSPORIN
1 KG Sep 30, 2024 Post an enquiry for this product