Supply Research Chemical Powder CAS 736992-21-5 Elamipretide

Elamipretide (also known as SS-31, , MTP-131 and Bendavia) is a small mitochondrially-targeted tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that appears to reduce the production of toxic reactive oxygen species and stabilize cardiolipin.

Mechanism of action of SS-31 against kidney disease. Mitochondria produce ATP and ROS through an electron transport chain consisting of complexes I to V. Ischemia, hypoxia, hyperglycemia, drugs, obstruction, genetic, and other risk factors can affect the kidneys, causing mitochondrial dysfunction and kidney disease. SS-31 protects mitochondrial structure, scavenges ROS, increases ATP supply, reduces cytochrome C release, and inhibits opening and calcium overload by binding to cardiolipin in the inner membrane of mitochondria, thereby exerting anti-oxidative stress, anti-inflammatory, antifibrotic, antiapoptotic, and autophagic effects.

It is a small molecule peptide composed of four amino acids, targeting the inner membrane of mitochondria in vivo, which can prevent oxidative damage to nerve cells and other cell types; Prevent mitochondrial depolarization, reduce pancreatic cell apoptosis, increase pancreatic cell production, and improve post transplant function.

Xi’an Fulecare biotech has high-technique enterprises with 10 years history,dedicate to separation, purification of the natural active ingredients production and sales.

We also produce international frontier dietary supplements such as granulated powder,solid drinks,tea sachets, capsules and tablets etc.

We have high grade clean workshop,800 square meters of inspection center equipped with more than 10 sets of HPLC,GC,IR,MASS instruments,these provides a full range of quality assurance to our products

The company has a perfect quality assurance system.We implement strict quality control standards and have passed the certification for the ISO9001 Quality Management System. The Quality Management Department is equipped with many sets of high performance liquid chromatography (HPLC)instruments, ultraviolet spectrophotometers (UV), several spectropolarimeters, a gas chromatograph (GC), melting point apparatus, and other advanced testing and experimental equipment. We make a detailed division of labor for technology research, and for quality assurance and quality control, so that we can conduct effective and comprehensive quality control in the production process. This also allows us to make comprehensive detection analysis of final products, thus ensuring products quality.