SS-31 | US Warehouse | Cosmetic Peptides | 99% Purity | 10mg 50mg Vials | Lyophilized Powder,High Quality Diacetin 99% liquid 25395-31-7 -Shaanxi Dide

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SS-31 (Elamipretide)  is a highly valuable mitochondrial-targeted peptide. Currently, no drugs based on this peptide have been approved for market release worldwide. The core mechanism of action of this peptide revolves around mitochondrial protection. Its unique molecular structure can precisely bind to the key lipid phosphatidylcholine within the mitochondrial inner membrane. On one hand, it stabilizes the mitochondrial membrane structure, prevents the decline of membrane potential and mitochondrial rupture, ensuring the normal energy synthesis function of mitochondria and maintaining the stable production of cellular ATP; on the other hand, it can efficiently eliminate reactive oxygen species (ROS) produced during mitochondrial metabolism - this is the main source of cellular oxidative stress. At the same time, it inhibits the mitochondrial-mediated apoptotic pathway, achieving multiple effects such as antioxidant, anti-inflammatory, and anti-apoptosis from the root cause, and repairing the damaged mitochondrial energy metabolism system. Compared with common antioxidants like vitamin C and glutathione, SS-31 has mitochondrial-specific targeting, does not need non-specific action in the cytoplasm, and its targeted and effective antioxidant and cell protection are far superior to traditional antioxidants. This is the core reason why it has become a research hotspot in the field of biomedicine. In scientific research on cell culture and animal models, SS-31 has demonstrated extensive potential application value. It can alleviate oxidative damage and cell apoptosis in various models of oxidative stress-related diseases such as cardiovascular diseases (myocardial ischemia-reperfusion injury, heart failure), neurological diseases (Alzheimer's disease, Parkinson's disease, cerebral ischemia), muscle-related diseases (muscular dystrophy, senile muscle atrophy), eye diseases (dry eye syndrome, retinopathy), acute kidney injury, liver injury, pulmonary fibrosis, etc., and can improve the physiological function of diseased tissues. At the same time, in studies related to aging and metabolism, it can reduce ROS accumulation in senescent cells, delay cell aging, and assist in regulating the body's metabolic balance.

Elamipretide (SS-31) is a small peptide that can reach inside the mitochondria and affect mitochondrial function maintenance. Elamipretide belongs to a family of cell-penetrating peptides that target and accumulate at the inner mitochondrial membrane. Inside the mitochondria, elamipretide binds to cardiolipin, an essential component of the inner mitochondrial membrane, and restores the mitochondria.

Given the effects of elamipretide on mitochondrial function and maintenance, treatment with elamipretide is under investigation to determine its benefits on human health. Recently, scientists have discovered at least four excellent benefits that can potentially make elamipretide a viable treatment option for a wide variety of conditions.

In diabetes research, SS-31 can improve mitochondrial dysfunction related to diabetes and has potential value in the treatment of diabetes and its complications. For sepsis, SS-31 can reduce vascular permeability in septic rats. The protective effect is related to the inhibition of oxidative stress, providing a new strategy for clinical treatment.