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Home > Active Pharmaceutical Ingredients > Antineoplastic Agents > Nintedanib for Sale > High Purity Nintedanib CAS 656247-17-5 API Raw Powders with Safety and Fast Delivery
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High Purity Nintedanib CAS 656247-17-5 API Raw Powders with Safety and Fast Delivery

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Unit Price: Get Latest Price
CAS No.:

656247-17-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

HyperChem

Packaging:

1kg/Bag, 25kg/drum

Price valid (until):

2026-05-10

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Description

    Name

    Nintedanib

    CAS number

    656247-17-5

    EINECS number

    1592732-453-0

    Synonym

    INTEDANIB BASE;Nintedanib (BIBF 1120);Nintedanib/Intedanib/Vargatef;BIBF 1120; VARGATEF; INTEDANIB;INTEDANIB BASE;Intedanib Vargatef;Nintedanib-016;100837;Nintedanib (Intedanib)

    Description

    Nintedanib is currently mainly used for tumor treatment, such as colorectal cancer, ovarian cancer, multiple myeloma, etc.

    Structure

    Shop High Purity Nintedanib CAS 656247-17-5 API Raw Powders with Safety and Fast Delivery-Detailed Image 1

    Molecular Formula

    C31H33N5O4

    Molecular Weight

    539.64g/mol

    Appearance

    Yellow-green powder

    Quality Standard

    In-house

    Assay

    99.5%

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China


    More Info

    Nintedanib is a tyrosine kinase inhibitor medication used to treat idiopathic pulmonary fibrosis , chronic fibrosing interstitial lung diseases with a progressive phenotype, and systemic sclerosis-associated ILD.

    Mechanism of Action

    Nintedanib blocks multiple receptor tyrosine kinases (VEGFR, FGFR, PDGFR), which are involved in the development of pulmonary fibrosis.



    Side Effects

     In addition to digestive issues (diarrhea, nausea), patients may experience elevated liver enzymes , decreased appetite , weight loss , and high blood pressure.


    Package Image

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    FAQ

    Q1. Can I get a free sample?

    We can send you a samll free sample, and you only need to pay for the shipping cost.


    Q2. What is the HyperChem payment term?

    T/T in advance
    LC at sight
    DP at sight

    Bank transfer

    PayPal

    Bitcoin...


    Q3. What is HyperChem shipment policy?

    Our policy is to strive for the quickest shipment time possible.

    For ready stock samples, they are usually shipped within 3 working days after payment received.
    For non-ready stock, please contact HyperChem sales team to negotiate.


    Q4. What is HyperChem shipment term?

    By Express  
    FedEx  UPS  DHL  EMS                               
    Fast: 3-7 days around, high cost, door to door service

    By Air                                        
    Suitable for more than 50kg 
    Fast: 3-7 days, hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Fast: 7-45 days, low cost, port to port, professional broker needed 


    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.


    Q5. What HyperChem will provide after shipment?

    For sample orders: 
    After shipment is done, an timely email including:

    1. Track details (Fedex /TNT/DHL/EMS Track number)
    2. Packaging photo
    3. COA, MSDS, etc
    4. Dispatch date & Estimated arriving time
    5. Shipping invoice

    For commercial orders
    A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.



    Company Profile

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.


    Among them, our key client industrial sectors around the global are:

    Pharmaceuticals
    Nutrition Ingredients/ Dietary supplements
    Cosmetic Ingredients
    Food Ingredients
    Veterinary API
    Agriculture fertilizer
    Custom Synthesis lab supply


    HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.




    Certificates

    Basic Info
    Product Name:

    Nintedanib

    Other Name:

    1H-Indole-6-carboxylic acid,2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-,methyl ester,(3Z)-;1H-Indole-6-carboxylic acid,2,3-dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-,methyl ester,(3Z)-;BIBF 1120;Nintedanib;Vargatef;Ofev;Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate;Methyl (Z)-3-[[[4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate;928326-83-4

    CAS No.:

    656247-17-5

    Molecular Formula:

    C31H33N5O4

    InChIKeys:

    InChIKey=XZXHXSATPCNXJR-ZIADKAODSA-N

    Molecular Weight:

    539.62482

    Exact Mass:

    539.62

    EC Number:

    1592732-453-0

    UNII:

    G6HRD2P839

    NCI Thesaurus Code:

    C62765

    ATC Code:

    L01XE3|L01XE|L - Antineoplastic and immunomodulating agents

    Categories:

    Antineoplastic Agents

    Characteristics
    PSA:

    94.2

    XLogP3:

    3.3

    Density:

    1.3±0.1 g/cm3

    Melting Point:

    305C

    Boiling Point:

    742.199°C at 760 mmHg

    Flash Point:

    402.7±32.9 °C

    Refractive Index:

    1.658

    Water Solubility:

    In water, 9.66 mg/L at 25 deg C (est)

    Storage Conditions:

    Store at 25 deg C (77 deg F); excursions permitted to 15 deg to 30 deg C (59 deg to 86 deg F). Protect from exposure to high humidity and avoid excessive heat. If repackaged, use USP tight container.

    Vapor Pressure:

    2.18X10-18 mm Hg at 25 deg C (est)

    Experimental Properties:

    Henry's Law contant = 2.42X10-24 atm-cu m/mol at 25 °C (est)|Hydroxyl radical reaction rate constant = 2.39X10-10 cu cm/molecule-sec at 25 °C (est)|Ozone radical reaction rate constant = 2.53X10-16 cu cm/molecule-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Skin irritation, Category 2

    Serious eye damage, Category 1

    Reproductive toxicity, Category 2

    Specific target organ toxicity – repeated exposure, Category 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H315 Causes skin irritation

    H318 Causes serious eye damage

    H361 Suspected of damaging fertility or the unborn child

    H372 Causes damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Country Product Purchase Quantity Date Posted
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