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GMP factory supply high purity semaglutide with DMF CAS 910463-68-2

Name: GMP factory supply high purity semaglutide with DMF CAS 910463-68-2
Brand: Bovita
SKU: pr2604102552
Price: 130 USD
Availability: InStock

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CAS No.:

910463-68-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Beijing

Brand:

Bovita

Packaging:

10g/aluminium foil bag

Price valid (until):

2026-05-10

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Bovitabiomed

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Peptides Powder,Dietary Supplements Powder,APIs Active Pharmaceutical Ingredientsal ingredient,Pharmaceutical Intermediates,Food Additives,Pharmaceuticals Machinery

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Product Description
Seller Information
Inquiry History

Description

Semaglutide Powder (CAS 910463-68-2)

Product Name: Semaglutide Powder

CAS Number: 910463-68-2

Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉

Molecular Weight:4113.64 g·mol⁻¹

Sequence: GLP‑1 receptor agonist peptide

1. Product Description

Semaglutide is a long‑acting glucagon‑like peptide‑1 (GLP‑1) receptor agonist, a synthetic peptide analog of human GLP‑1. It features a fatty acid side chain that enables strong albumin binding, greatly prolonging its half‑life and allowing for sustained pharmacological activity.

Our Semaglutide Powder is a white to off‑white lyophilized powder with high purity and excellent stability, manufactured under strict GMP‑compliant conditions for reliable batch consistency.

Item	Specification
Assay (HPLC)	≥98.0%
Appearance	White to off‑white lyophilized powder
Water Content	≤5.0%
Acetate Content	4.0% – 12.0%
Total Impurities	≤2.0%
Single Unknown Impurity	≤0.5%
Bacterial Endotoxins	≤5 EU/mg
Peptide Purity	≥98.0%

3. Mechanism of Action

Selectively activates GLP‑1 receptors in a glucose‑dependent manner.
Stimulates insulin secretion and suppresses glucagon release, lowering blood glucose.
Delays gastric emptying, reduces appetite and food intake.
Promotes weight loss and improves metabolic parameters.
Long half‑life supports once‑weekly administration in finished formulations.

4. Main Applications

Pharmaceutical API: For development and production of injectable preparations for type 2 diabetes mellitus and chronic weight management.
Research & Development: Used in preclinical pharmacology, toxicology, and formulation studies.
Biomedical Research: For studies related to metabolism, obesity, diabetes, and cardiovascular protection.

5. Our Advantages

High purity: ≥98.0% by HPLC, low impurities, suitable for R&D and formulation.
Stable quality: Strict quality control and full analytical data (COA, HPLC, MS, NMR).
Professional production: Manufactured in cleanroom environment with strict contamination control.
Secure packaging: Lyophilized bottles, aluminum foil bags, and sealed drums to preserve peptide stability.
Complete documentation: COA, MSDS, HPLC, NMR, stability data available on request.

6. Storage & Handling

Storage: Store at ‑20°C or below, protected from light and moisture.
Transport with ice packs or dry ice to maintain stability.
Shelf Life: 2 years under proper storage conditions.
Avoid repeated freeze‑thaw cycles.
Wear protective equipment during handling; avoid inhalation and skin contact.

7. Safety & Compliance Notice

For research and industrial manufacturing use only.
Not for direct human or animal administration.
Strictly comply with local laws and regulations regarding peptide APIs and controlled substances.
Full safety data (MSDS) provided with each order.

8. Packaging & Shipping

Packing: 1g, 5g, 10g, 100g, 500g, 1kg sealed containers; customizable.
MOQ: Negotiable, supports small‑batch R&D orders.
Lead Time: In‑stock items shipped within 2–3 working days.
Shipping: Cold chain transport via DHL, FedEx, UPS, air or sea.

ECHEMI Editorial Reference

Semaglutide (CAS: 910463‑68‑2) is a synthetic lipid‑modified peptide analogue, consisting of a 31‑amino‑acid backbone with a covalently attached C18 fatty di‑acid side‑chain via a hydrophilic spacer. It shares 94% amino‑acid sequence homology with native human GLP‑1 peptide. The substance appears as white to almost white hygroscopic powder, with molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and molecular weight of 4113.58 g/mol. Structural modifications grant it resistance against DPP‑4 enzymatic degradation and enable reversible binding to serum albumin, contributing to its extended in‑vivo half‑life property.

Certificates

Basic Info

Product Name:

Semaglutide

Other Name:

Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide

CAS No.:

910463-68-2

Molecular Formula:

C187H291N45O59

InChIKeys:

DLSWIYLPEUIQAV-CCUURXOWSA-N

Molecular Weight:

4113.57754

Exact Mass:

4113.122087 g/mol

EC Number:

203-405-2

Color/Form:

White to off-white

Categories:

Polypeptide

Characteristics

PSA:

1650 Å²

XLogP3:

5.44520

Critical Temperature & Pressure:

Store at -20°C

Research

Class:

GLP-1R agonist

Status:

FDA-approved (Ozempic / Wegovy / Rybelsus)

Mechanism:

Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

Activity note:

Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

Source:

Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

Clinical Development:

NCT03548935; NCT03552757; NCT01720446; NCT02692716

FDA:

Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)

Disclaimer:

Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

See More Semaglutide Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H361 Suspected of damaging fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Semaglutide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Peptides Powder,Dietary Supplements Powder,APIs Active Pharmaceutical Ingredientsal ingredient,Pharmaceutical Intermediates,Food Additives,Pharmaceuticals Machinery

Location:
Room 403 No.62 of Shan Shui Huihao Gardan, Dou Dian Town,Fangshan District, Beijing,China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2026

Bovita is a forward-thinking biotech startup specializing in high-purity peptide products and premium dietary supplement raw materials. Rooted in the rigorous standards of China’s pharmaceutical and chemical industry, we are dedicated to bridging scientific excellence with global wellness demands, with a core focus on serving the North American and European markets.

Company Profile

Inquiry History

489 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Weight Loss Semaglutide intermediate 99% White powder COA High Quality peptide GLP-1 910463-68-2	5 MG	Apr 11, 2024
United States	Gene-Biocon Semaglutide 910463-68-2 GLP-1analogs diabetes weight loss 96% White or off-white powder	2	Dec 5, 2023
United States	Semaglutide 910463-68-2	1 G	Sep 21, 2023
United States	Sermaglutide 99% 910463-68-2	2 KG	Oct 21, 2023
China	Semaglutide CAS 910463-68-2	1 KG	Apr 16, 2026
United Kingdom	TGYFactory Supply Semaglutide Peptide 99% CAS 910463-68-2	50 MT	Nov 13, 2023
Switzerland	Semaglutide Ozempic Sermaglutide 99.9% white powder 910463-68-2 Teruiop	5000 MT	Sep 13, 2023
United States	High Purity Peptide Semaglutide 910463-68-2 With Safe Shipping	1 G	Sep 7, 2023
Sri Lanka	Bulk Supply 98% up Sermaglutide powder CAS 910463-68-2	300 G	Nov 18, 2023
United States	Semaglutide Ozempic Sermaglutide 99.9% white powder 910463-68-2 Teruiop	500 G	Oct 9, 2023
United States	Raw mateiral Semaglutide CAS 910463-68-2 99% White powder	1000 G	Sep 23, 2023
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	10 MT	Sep 19, 2025
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	2	Nov 13, 2024
United States	semaglutide CAS 910463-68-2 in stock 2-4 days safe delivery	1 MT	Nov 4, 2023
United Kingdom	API Pharmaceutical Chemical Grade Raw Materials CAS 910463-68-2 Semaglutide	40 MT	Sep 27, 2023
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	10	Sep 27, 2023
United States	10MG vial pack Semaglutide 99% 910463-68-2 GLP-1 Peptide	10 MT	Oct 18, 2023
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	60 MG	Aug 4, 2025
India	Best Price 99% Semaglutide Peptide 10mg Vials Semaglutide CAS 910463-68-2	100	Nov 8, 2023
China	Semaglutide Tirzepatide for Weight Loss CAS: 910463-68-2 Retatrutide Cagrilintide	1 MT	Jul 5, 2025

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