Supply Health Product Antidepressant Raw Powder CAS 138112-76-2 Agomelatine
TDS 2 Inquiries
138112-76-2
Pharmaceutical Grade
99%
Shanghai
HNB
1kg/bag, 25kg/drum or as request
2026-05-14
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceAgomelatine is a competitive antagonist of human and porcine serotonin (5-HT2C) receptors (pKi = 6.2 and 6.4, respectively) as well as human 5-HT2B receptors (pKi = 6.6). IC50 value: 6.2 (pKi, 5-HT2c); 6.6 (pKi, 5-HT2b)Target: 5-HT2C Receptor; 5-HT2B receptorIt is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of 5-HT2C results in
Solid
Agomelatine is a member of acetamides.|Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines Agency (EMA) in 2005. The Committee for Medical Products for Human Use (CHMP) recommended refusal of marketing authorization on 27 July 2006. The major concern was that efficacy had not been sufficiently shown. In 2006 Servier sold the rights to develop Agomelatine in the US to Novartis. The development for the US market was discontinued in October 2011. It is currently sold in Australia under the Valdoxan trade name.CertificatesBasic Info-
Product Name:
Agomelatine
Other Name:Acetamide,N-[2-(7-methoxy-1-naphthalenyl)ethyl]-;N-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide;S 20098;N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide;Agomelatine;Valdoxan;N-[2-(7-Methoxynaphthalen-1-yl)ethyl]acetamide;AGO 178;Thymanax
CAS No.:138112-76-2
Molecular Formula:C15H17NO2
InChIKeys:InChIKey=YJYPHIXNFHFHND-UHFFFAOYSA-N
Molecular Weight:243.30100
Exact Mass:243.30
UNII:137R1N49AD
DSSTox ID:DTXSID3057642
ATC Code:N06AX22|N - Nervous system
HScode:2924199090
Categories:
Characteristics-
PSA:
38.33000
XLogP3:2.7
Appearance:white solid
Density:1.109g/cm3
Melting Point:109-110 °C @ Solvent: Toluene, Hexane
Boiling Point:478.8ºC at 760 mmHg
Flash Point:243.4ºC
Refractive Index:1.582
Water Solubility:7.76e-03 g/L
Collision Cross Section:156.3 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]
Hazard IdentificationClassification of the substance or mixture
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H400 Very toxic to aquatic life
Precautionary statement(s) Prevention P273 Avoid release to the environment.
Response P391 Collect spillage.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Location:
6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China
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Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2017
Company Certificates-
ISO
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ISO
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
United States
Agomelatine
30 G Apr 28, 2026 
Sweden
Agomelatine
25 G Feb 4, 2024 Post an enquiry for this product
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