Abaloparatide peptide API

Product Usage

Abaloparatide belongs to a class of medications known as parathyroid hormone-related protein (PTHrP) analogs. It is a synthetic peptide analog of human parathyroid hormone-related protein (PTHrP), specifically its N-terminal fragment (1-34). Abaloparatide selectively binds to the parathyroid hormone type 1 receptor (PTH1R), activating the signaling pathway that stimulates bone formation.

Abaloparatide is indicated for the treatment of postmenopausal women with osteoporosis at high risk for fracture. It works by increasing bone mineral density (BMD) and reducing the risk of vertebral and non-vertebral fractures. Unlike anti-resorptive therapies that slow bone loss, abaloparatide is an anabolic agent that stimulates new bone formation.

Clinical studies have demonstrated that abaloparatide significantly increases bone mineral density at the lumbar spine, femoral neck, and total hip. In the ACTIVE clinical trial, abaloparatide reduced the risk of new vertebral fractures by 86% and non-vertebral fractures by 43% compared to placebo over 18 months.

Key Benefits:

• Increases bone formation and mineral density

• Reduces vertebral and non-vertebral fracture risk

• Once-daily administration

• Well-established safety profile for up to 2 years of treatment

How much improvement can you expect with abaloparatide?

Clinical trials have shown that patients taking abaloparatide experienced an average increase in lumbar spine bone mineral density of approximately 11% over 18 months, significantly reducing fracture risk.

FAQ

1. May I get a sample before placing an order?

Yes, samples are available. For regular products, samples are free of charge and you only need to bear the freight. For high-value products, you need to pay for the freight and a certain product cost. When we cooperate for some time or when you become our VIP customer, free samples will be offered when needed.

2. Which payment methods are available for your company?

T/T, PayPal, bank transfer, and other options. You can choose the one that is most convenient for you.

3. How and when can I get my goods after payment?

For small quantities, products will be delivered by international courier (DHL, FedEx, TNT, etc.) or by air. Usually, it takes 5-7 days to receive the goods after shipment. For large quantities, shipping by sea is more cost-effective. It takes 15-30 days to reach your destination port, depending on the port location.

4. Is it possible to use my own label or packaging?

Yes. If needed, we can accommodate custom labeling and packaging requirements. Please provide your specifications and we will confirm feasibility.

5. What is the purity and quality standard of your Abaloparatide API?

Our Abaloparatide API is manufactured under cGMP standards with purity ≥99% by HPLC. We provide comprehensive documentation including COA, stability data, and DMF filing support.

6. What is the recommended storage condition?

Store at -20°C ± 5°C, dry, protected from light. The shelf life is 24 months under recommended storage conditions.

7. Do you provide regulatory support for filing?

Yes, we provide regulatory support including DMF filing assistance, documentation packages, and technical support for customer submissions.

Company Profile

Hangzhou ThinHeal Pharma-Tech Co., Ltd. (ThinHeal) is a high-tech enterprise specializing in the research, development, production, and sales of peptide products. The core management team is composed of professionals with a pharmaceutical background and nearly 20 years of management experience, positioning the company at the forefront of the industry.

The company has a complete and efficient peptide R&D, production, and sales system, and provides a full range of peptide industrialization services, including:

• Peptide API R&D and production business

• Peptide customized R&D and production (CDMO) business

• Beauty peptide research, development, and production business

The company's revenue is mainly derived from peptide API sales and CDMO services. The company has successfully completed US FDA DMF filings for multiple products. The CDMO business includes project-based entrusted research and development, entrusted production, and sales. The main customers of the CDMO business are innovative drug companies and scientific research institutions, among which some pharmaceutical companies have cooperated with ThinHeal since the product development stage and have established solid cooperative relationships.

ThinHeal is committed to providing high-quality peptide APIs and comprehensive technical support to customers worldwide, with a focus on regulatory compliance, supply chain reliability, and customer satisfaction.