3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride 202646-03-5

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Product Name: 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride Synonyms: 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride;)-17-[[2-(8-Nonen-1-yl)-1,3-dioxo-12-tridecen-1-yl]oxy]androsta-1,4-dien-3-one;-methyl-1-(nitromethyl)-5α-Estradiol-d5 Cyclic Ethylene Acetal;-METHYL-2α-OH Gibberellin A3;)-7-Hydroxy-3,24-dioxochol-4-en-24-yl]glycine CAS: 202646-03-5 MF: C21H24ClF2NO MW: 379.8711664 EINECS: Product Categories: Mol File: 202646-03-5.mol 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride Chemical Properties solubility  Soluble to 100 mM in DMSO form  Powder color  White to yellow Safety Information MSDS Information 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride Usage And Synthesis Description Potent inhibitor of dopamine uptake and transport (Ki= 18 nM). Uses 3α-Bis-(4-fluorophenyl) Methoxytropane Hydrochloride is a potent inhibitor of dopamine uptake and transport. in vivo AHN 1-055 (5 mg/kg; i.v.) inhibits the uptaking of brain dopamine with an IC50 of 311.8 ng/ml in vivo[1]. AHN 1-055 (10 mg/kg; i.v.) exhibits Cmax of 1.48 mg/L and terminal elimination half-lives of 7.69 h due to 1.8L/h/kg plasma clearance combined with 18.7 L/kg volumes of distribution[1]. Animal Model: Adult male Sprague Dawley rats (250-275 g)[1] Dosage: 5mg/kg (Pharmacokinetic Analysis) Administration: I.v. administration Result: Cmax (1.48 mg/L); T1/2 (7.69 h).

First aid measures

General advice Consult a physician. Show this material safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Firefighting measures

Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture Carbon oxides Nitrogen oxides (NOx) Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.



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