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O-304 1261289-04-6

33 Inquiries

Unit Price:

$45-56/MT FOB

Get Latest Price
CAS No.:

1261289-04-6

Grade:

Industrial Grade

Content:

99%

Port:

sh

Brand:

orient

Packaging:

1KG, 5KG, 25KG

Price valid (until):

2026-10-04

Company Type:
Trader
Location:
China
Qualification:
Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Product Name: Dermorphin
    Synonyms: DERMORPHIN ACETATE;L-Tyr-D-Ala-L-Phe-Gly-L-Tyr-L-Pro-L-Ser-NH2;Tyrosyl-alanyl-phenylalanyl-glycyl-tyrosyl-prolyl-serinamide;Dermorphin trifluoroacetate salt;Dermorphin Powder;(2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide;Dermorphin HAc;(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-1-carbamoyl-2-hydro
    CAS: 77614-16-5
    MF: C40H50N8O10
    MW: 802.87
    EINECS: 202-853-6
    Product Categories: 77614-16-5
    Mol File: 77614-16-5.mol
    Shop Dermorphin 77614-16-5 API-Detailed Image 1

    Dermorphin Chemical Properties
    Melting point  157-159 °C
    Boiling point  1323.8±65.0 °C(Predicted)
    density  1.363±0.06 g/cm3(Predicted)
    storage temp.  -20°C
    solubility  Soluble in DMSO
    form  powder
    pka 9.83±0.15(Predicted)
    color  white to off-white
    Sequence H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2
    InChIKey FHZPGIUBXYVUOY-VWGYHWLBSA-N
    SMILES C(N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N)(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](C)NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)CC1C=CC=CC=1)CC1C=CC(O)=CC=1

    Safety Information
    WGK Germany  3
    MSDS Information


    Dermorphin Usage And Synthesis
    Structure Dermorphin does not contain the common N-terminal sequence for the traditional endogenous  peptides (Tyr–Gly–Gly–Phe), and its sequence is completely different from those of the endomorphins, which were identified as endogenous μ- peptides that also do not contain the common sequence. Interestingly, DM contains D-alanine (a D-isomer amino acid) in its sequence. The primary structure of dermorphin is YDAFGYPS-NH2.
    Description Dermorphin was first isolated from the skin of the skin of South American frogs of the genus Phyllomedusa.  It is a high potency natural opiate peptide that binds selectively to mu- receptors.
    Uses A mu- receptor agonist
    Definition ChEBI: Dermorphin is an oligopeptide.
    Side effects Like μ-opiate agonists, dermorphins produce antinociception and also catalepsy, respiratory depression, constipation, tolerance, and dependence, although at a lower degree than   does[1].
    in vitro Dermorphin, a peptide isolated from the skin of Phyllomedusa frogs and the peptide receptor (NOP) component by the endogenous agonist nociceptin/orphanin FQ (N/OFQ). In displacement binding studies at CHOhMu, Dermorphin and DeNo displac the binding of [3H]-DPN in a concentration dependent and saturable manner. Dermorphin displays an affinity of 7.17, while N/OFQ fails to displace [3H]-DPN at the Delta receptor. Dermorphin and DeNo stimulate the binding of GTPγ[35S] in a concentration dependent and saturable manner at the Mu receptor.
    References [1] Negri, L. P. Melchiorri and R. Lattanzi. “ and Bv8 Peptides.”Handbook of Biologically Active Peptides (Second Edition) 2013:376-383.

    Shop Dermorphin 77614-16-5 API-Detailed Image 2 Shop Tirzepatide API Material-Detailed Image 4


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    Shop Tirzepatide API Material-Detailed Image 7


    Shop Tirzepatide API Material-Detailed Image 8

    Shop Tirzepatide API Material-Detailed Image 9

    Shop Tirzepatide API Material-Detailed Image 10


    Shop Tirzepatide API Material-Detailed Image 11

    Q1:Do you provide sample?

    A: Yes, we can provide free sample, you only need pay the shipping cost.

    Q2: What is the lead time?

    A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

    Q3: How can I buy? What is the payment method?

    A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer, 

    Q4:What if there are quality issues?

    A:We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

    Basic Info
    Product Name:

    O-304

    Other Name:

    O-304;O-304 1261289-04-6;4-chloro-N-(2-(4-chlorobenzyl)-3-oxo-2,3-dihydro-1,2,4-thiadiazol-5-yl)benzamide;CS-2682;0 304;O-304;0 304;Benzamide, 4-chloro-N-[2-[(4-chlorophenyl)methyl]-2,3-dihydro-3-oxo-1,2,4-thiadiazol-5-yl]-;O 304,AMPK,O-304,inhibit,Inhibitor,AMP-activated protein kinase,O304

    CAS No.:

    1261289-04-6

    Molecular Formula:

    C16H11Cl2N3O2S

    InChIKeys:

    WEDWLYRQKUTOAX-UHFFFAOYSA-N

    Molecular Weight:

    380.25

    Exact Mass:

    378.995

    EC Number:

    202-303-5

    Color/Form:

    White to off-white

    Categories:

    Inhibitor Drugs

    Characteristics
    PSA:

    92.23

    XLogP3:

    3.9852

    Density:

    1.50±0.1 g/cm3(Predicted)

    PKA:

    7.81±0.20(Predicted)

    Critical Temperature & Pressure:

    Store at -20°C

  • Seller Information
    Business Type:

    Trader

    Main Products:

    pharmaceutical intermediates,peptides,electronic chemicals

    Location:

    Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

    Payment Terms:

    100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    51-100

    Year of Establishment:

    2024

    A reliable supplier is like insurance.

    We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals,food additives, and other fine chemical products.
    Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

    Website: orientchem.cc
    Email: scarlett@orientchem.cc
    WhatsApp: +86 17753254221

  • Inquiry History
    33 Inquiries
    Country Product Purchase Quantity Date Posted
    Russia

    Factory Supply Pure 99% CS-2682 O304 O-304 Powder CAS 1261289-04-6

    200 G Aug 9, 2025
    Denmark

    Factory Supply Pure 99% CS-2682 O304 O-304 Powder CAS 1261289-04-6

    500 G Oct 23, 2025
    United States

    ATX-304/O-304

    15 G Sep 12, 2026
    Portugal

    O-304

    100 G Apr 30, 2026
    Philippines

    O-304

    9 KG Aug 31, 2026
    Germany

    O-304

    10 G Sep 4, 2026
    Thailand

    O-304

    100 G Sep 1, 2026
    France

    RTX-304

    20 MG Aug 13, 2026
    United States

    o-304 atx-304

    100 G Jun 22, 2026
    Canada

    ATX-304

    10 G Jun 16, 2026
    United States

    ATX304 / O304

    50 G May 28, 2026
    Singapore

    ATX-304

    100 G May 23, 2026
    Slovakia

    ATX-304 (O-304)

    1 KG Mar 9, 2026
    United States

    Atx-304

    30 G Nov 25, 2025
    Germany

    ATX-304 / O-305

    10 G Sep 11, 2026
    United States

    ATX-304

    500 G Aug 23, 2026
    United States

    Atx-304/O-304

    10 G Aug 10, 2026
    United States

    ATX-304 (O-304) raw powder

    10 G Jul 26, 2026
    United States

    atx-304

    1 G May 28, 2026
    United States

    O-304

    1 KG May 14, 2026
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