Basic Parameter Information
Full Name: AHK-Cu (Copper Tripeptide-3, L-Alanyl-L-Histidyl-L-Lysine Copper Complex)
Amino Acid Sequence: H-Ala-His-Lys-OH chelated with Cu²⁺
Molecular Formula: C₁₅H₂₄CuN₆O₄
Molecular Weight: 415.93 g/mol
CAS Number: 682809-81-0
Appearance: Sterile lyophilized light blue crystalline powder, individually sealed in vials (main specifications: 10mg / 50mg / 100mg)
Purity: ≥98% verified via HPLC, full COA quality inspection records provided for each batch
R&D Background: AHK-Cu is a synthetic copper-chelated tripeptide, formed by stable coordination between the AHK amino acid chain and divalent copper ions. Copper acts as a vital cofactor for tissue repair enzymes, antioxidant proteins and follicular developmental signaling pathways. This lab-grade complex material is developed for dermal fibroblast cultivation, hair follicle cell testing, cutaneous remodeling assays and oxidative stress cell model research, widely applied in dermatology, hair follicle biology and cosmetic raw material mechanism laboratory projects.
2. Core Mechanism of Action
AHK-Cu delivers bioavailable copper into target cells while functioning as a signal regulator, activating multi-layer regenerative and protective signal networks within skin and follicle cell culture systems:
Bind copper transport proteins on dermal papilla and fibroblast surfaces to deliver trace copper intracellularly, supporting catalytic activity of collagen-building enzymes and endogenous antioxidant proteins such as SOD;
Trigger Wnt/β-catenin signaling inside hair follicle precursor cells, boost proliferation vitality of follicular stem cells and extend the active growth cycle of follicles under long-term in vitro culture conditions;
Lower excessive expression of fibrosis-related growth factors in dermal cell populations, restrain abnormal tissue hardening around follicles and maintain soft regenerative microenvironment for epithelial tissue samples;
Stimulate secretion of vascular growth signaling molecules from fibroblasts, promote assembly of microvascular tubular networks to improve nutrient exchange efficiency in skin and scalp tissue co-culture models;
Elevate intracellular antioxidant reserves to clear reactive oxidative metabolites, reduce oxidative damage that triggers follicle shrinkage and slow age-related dermal cell functional decline;
Balance mild inflammatory mediator release from resident skin immune cells, ease low-grade persistent irritation that disrupts regular follicle cycling and epidermal tissue turnover.
3. Core Research Efficacy (For Research Laboratory Use Only)
Hair Follicle & Dermal Papilla Cell Research
Core experimental probe for cultivating follicular precursor cells and observing follicle growth cycle regulation; suitable for follicle elongation and stem cell proliferation quantitative detection assays.
Dermal Collagen Synthesis & Skin Remodeling Research
Key raw material for exploring fibroblast extracellular matrix generation pathways, supporting cell-level analysis of cutaneous tissue reconstruction and anti-fibrosis mechanisms.
Microvascular Angiogenesis & Tissue Perfusion Research
Auxiliary testing material for endothelial tubular network formation experiments, applied to research on nutrient circulation improvement within scalp and dermal tissue models.
Cellular Antioxidant & Anti-Aging Mechanism Research
Reduce free radical accumulation in skin and follicle cells, supporting testing on oxidative lesion relief and age-related follicle function maintenance.
Cutaneous Mild Inflammatory Balance Research
Modulate disordered low-level inflammatory signal output, ideal for laboratory analysis of irritation-induced follicle growth suppression and epidermal barrier stabilization pathways.
Supplied as sterile lyophilized light blue crystalline powder with HPLC-tested purity ≥98%, mainstream vial specifications include 10mg, 50mg and 100mg. Every batch comes with complete supporting documents including COA, MSDS and HPLC chromatogram test data.
As a copper-carrier tripeptide complex reagent, AHK-Cu combines trace mineral delivery, follicular regeneration promotion and dermal repair regulatory functions. Its compact three-amino-acid chelated structure brings outstanding water solubility and steady cell permeability, delivering consistent target binding activity across diverse in vitro skin, fibroblast and hair follicle cell culture research systems.
It serves as indispensable research material for cell cultivation and tissue model experiments covering hair follicle developmental biology, dermal extracellular matrix synthesis, microvascular formation and cutaneous oxidative defense research.
Note: For laboratory research use only, not approved for human oral consumption or clinical therapeutic treatment.
We maintain sufficient stable stock, complete export certification paperwork, door-to-door double clearance logistics service with full real-time shipment tracking available for all orders.
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