Core Product Specifications
Amino Acid Sequence: Ala-Glu-Asp-Pro (AEDP) – a linear tetrapeptide with a molecular formula of C₁₇H₂₆N₄O₉ and an exact molecular weight of 430.41 Da.
Purity: ≥99.0% (HPLC & MS verified), exceeding standard research-grade benchmarks, with zero detectable impurities or residual solvents.
Form: White, lyophilized powder, sealed in sterile, vacuum-sealed vials for maximum stability.
Standard Packaging: 10mg/vial, 20mg/vial; customizable bulk packaging available (from trial samples to kilogram-scale orders).
Storage: Lyophilized powder stable for 24+ months at -20°C (dry, light-protected); reconstituted solutions stable for 21 days at 2–8°C or 6 months at -20°C.
Solubility: Highly soluble in water, PBS, and physiological saline; insoluble in organic solvents.
Premium Quality & Manufacturing Excellence
Our Cortagen Premium is produced under strict GMP-compliant conditions in a Class 100 cleanroom, utilizing advanced solid-phase peptide synthesis (SPPS) technology. Every batch undergoes rigorous quality control:
Dual Purity Testing: In-house HPLC analysis followed by third-party mass spectrometry (MS) validation to confirm ≥99.0% purity.
Impurity Screening: Zero heavy metals, endotoxins (<0.01 EU/mg), and microbial contaminants, with full COA (Certificate of Analysis) and MSDS provided for every order.
Stability Assurance: Optimized lyophilization process preserves peptide integrity, ensuring consistent activity across storage and transportation.
Mechanism of Action & Research Applications
Cortagen Premium acts as a potent CNS bioregulator, crossing the blood-brain barrier efficiently to modulate gene expression in cerebral cortex neurons and glial cells. Its key mechanisms include:
Epigenetic Regulation: Modulates chromatin structure and activates neurotrophic factor genes (BDNF, NGF), supporting synaptic plasticity and neuronal survival.
Oxidative Stress Reduction: Inhibits lipid peroxidation and enhances endogenous antioxidant systems, protecting neurons from age-related damage.
Neuroregeneration: Stimulates nerve fiber growth (27–40% increase in preclinical models) and accelerates recovery from cerebral ischemia and neural injury.
Primary research applications include:
Cognitive Aging: Improves spatial memory, attention, and executive function in aged animal models.
Neuroprotection: Reduces neuronal apoptosis and preserves cortical thickness in neurodegenerative models.
Neural Repair: Enhances recovery from stroke, traumatic brain injury, and peripheral nerve damage.
Geroprotection: Reverses age-related gene silencing and promotes cellular rejuvenation in neural tissue.
In-Stock Advantage & Global Logistics
We maintain a permanent, large-scale inventory of Cortagen Premium to eliminate lead-time delays and support urgent research timelines. Key benefits:
Immediate Availability: All standard vial sizes (10mg, 20mg) are in stock; orders ship within 1–3 business days after confirmation.
Global Shipping: Temperature-controlled packaging and expedited logistics (air, sea, express) ensure product integrity during transit.
Regulatory Compliance: Complete documentation (COA, MSDS, customs clearance forms) provided to meet import requirements in North America, Europe, Asia, and Oceania.
Bulk & Custom Orders: Flexible production capacity to fulfill large-scale framework agreements and custom packaging requests.
Technical Support & Customer Commitment
Our team of peptide scientists provides complimentary technical support for all Cortagen Premium purchasers:
Storage & Reconstitution Guidance: Detailed protocols to maximize peptide stability and activity.
Research Dosage Recommendations: Evidence-based dosing ranges for in vitro and in vivo studies.
Product Troubleshooting: Direct access to experts for experimental design and result optimization.
Cortagen Premium is exclusively for research use only and is not intended for human or veterinary diagnostic or therapeutic applications. It is not a drug, food, or cosmetic and should not be used as a substitute for medical advice.
Why Choose Cortagen Premium?
In an era of advancing neuroscience research, Cortagen Premium delivers unmatched purity, stability, and targeted neurobiological activity. Our commitment to quality control, immediate stock availability, and global support makes us the trusted supplier for leading research institutions and biotech companies worldwide. Whether for small-scale pilot studies or large-scale preclinical programs, Cortagen Premium provides the reliability and performance required to drive breakthrough discoveries in neuroprotection and cognitive health.
United States