Full Name: Chonluten Cartilage Bioregulatory Tripeptide
Amino Acid Sequence: H-Glu-Asp-Gly-OH
Molecular Formula: C₁₂H₁₉N₃O₈
Molecular Weight: 333.29 g/mol
CAS Number: Custom synthetic peptide without assigned public CAS registry number
Appearance: Sterile lyophilized white crystalline powder, individually sealed in separate vials (main specifications: 10mg / 20mg / 50mg)
Purity: ≥99% validated via HPLC testing, complete COA quality inspection documentation provided with every production batch
R&D Background: Chonluten is a targeted short tripeptide bioregulator developed for cartilage and connective tissue research, isolated from active functional fragments of natural cartilage tissue polypeptides. This high-purity synthetic laboratory material is tailored for chondrocyte cultivation, extracellular matrix synthesis testing, joint tissue degenerative cell model analysis and inflammatory cartilage lesion mechanism exploration. It is widely applied in orthopedic cell biology, cartilage regenerative research and age-related connective tissue pathology laboratory projects.
2. Core Mechanism of Action
Chonluten penetrates chondrocyte cell structures and interacts with gene promoter segments linked to cartilage formation, activating multi-layer protective and regenerative signaling networks within in vitro tissue culture systems:
Stimulate proliferation activity of primary chondrocyte precursor cells, promote steady expansion of viable cartilage cell populations during long-term incubation cycles;
Upregulate gene expression of core cartilage matrix components including collagen and proteoglycans, support the continuous deposition of structural substances that maintain cartilage tissue elasticity and integrity;
Restrain overactive breakdown enzyme expression triggered by inflammatory stimulation, slow excessive degradation of extracellular matrix inside damaged joint tissue co-culture models;
Adjust balanced release of inflammatory signaling mediators in cartilage resident cells, reconstruct a mild non-destructive microenvironment to reduce persistent inflammatory erosion of chondrocyte structures;
Strengthen endogenous antioxidant defense systems within cartilage cells, clear accumulated oxidative metabolites that accelerate tissue aging and suppress degenerative functional decline;
Optimize intercellular signal communication between chondrocytes and synovial tissue cells, ease abnormal metabolic imbalance induced by long-term mechanical simulation and inflammatory stress.
3. Core Research Efficacy (For Research Laboratory Use Only)
Chondrocyte Proliferation & Cartilage Matrix Synthesis Research
Core experimental probe for culturing cartilage primary cells, suitable for quantitative detection of collagen and proteoglycan secretion as well as extracellular matrix formation assays.
Degenerative Joint Tissue Cell Model Research
Key raw material for exploring cartilage aging and degenerative damage pathways, supporting cell-level experiments simulating age-related joint tissue function loss.
Cartilage Anti-Inflammatory & Lesion Repair Research
Auxiliary testing reagent for inflammatory cartilage co-culture systems, applied to mechanistic study of inflammatory matrix degradation inhibition and tissue reconstruction.
Cellular Oxidative Stress & Cartilage Anti-Aging Research
Reduce free radical accumulation inside chondrocytes, ideal for laboratory analysis of oxidative damage relief and cartilage cell vitality maintenance pathways.
Synovial-Chondrocyte Co-Culture Crosstalk Research
Balance interactive metabolic signals between synovial tissue and cartilage cells, supporting exploration of joint tissue microenvironment homeostasis regulatory mechanisms.
Supplied as sterile lyophilized white crystalline powder with HPLC-certified purity ≥99%, mainstream vial specifications include 10mg, 20mg and 50mg. Every batch is attached with full supporting documents covering COA, MSDS and HPLC chromatogram test records.
As a cartilage-specific short tripeptide laboratory reagent, Chonluten integrates chondrocyte proliferation promotion, extracellular matrix synthesis enhancement and cartilage inflammatory relief functions. Its compact three-amino-acid chain delivers outstanding cell permeability and consistent target regulatory activity across diverse in vitro chondrocyte, synovial and joint tissue co-culture research systems.
It serves as indispensable research material for cell cultivation and tissue model experiments covering cartilage regenerative biology, connective tissue matrix metabolism, joint inflammatory balance and age-related cartilage degenerative research.
Note: For laboratory research use only, not approved for human oral consumption or clinical therapeutic treatment.
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