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L-Carnosine 305-84-0 C9H14N4O3

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CAS No.:

305-84-0

Grade:

Pharmaceutical Grade

Content:

99.99%

Port:

shanghai

Brand:

Packaging:

BOTTLE

Price valid (until):

2026-06-14

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Product Name:	L-Carnosine
Synonyms:	N-B-ALANYL-L-HISTIDINE;H-BETA-ALA-HIS-OH;L-IGNOTINE;L-BETA-ALANINE HISTIDINE;L-CARNOSINE;B-ALANYL-L-HISTIDINE;BETA-A-H;BETA-ALANYL-L-HISTIDINE
CAS:	305-84-0
MF:	C9H14N4O3
MW:	226.23
EINECS:	206-169-9
Product Categories:	Food additive;amino;Amino Acids;chiral;Nutritional Supplements;API;Amino Acid Derivatives;cosmestic;APIs;305-84-0
Mol File:	305-84-0.mol

L-Carnosine Chemical Properties

Melting point	253 °C (dec.) (lit.)
alpha	20.9 º (c=1.5, H2O)
Boiling point	367.84°C (rough estimate)
density	1.2673 (rough estimate)
vapor pressure	0Pa at 25℃
refractive index	21 ° (C=2, H2O)
storage temp.	-20°C
solubility	DMSO (Very Slightly), Water (Slightly)
pka	2.62(at 25℃)
form	crystalline
color	White
Odor	at 100.00%. odorless
Optical Rotation	+24.120
Water Solubility	almost transparency
Merck	14,1850
BRN	87671
Stability:	Stable, but may be heat sensitive - store cold. Incompatible with strong oxidizing agents.
Major Application	food and beverages personal care pharmaceutical
Cosmetics Ingredients Functions	SKIN CONDITIONING
InChI	1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1
InChIKey	CQOVPNPJLQNMDC-ZETCQYMHSA-N
SMILES	NCCC(=O)N[C@@H](Cc1c[nH]cn1)C(O)=O
LogP	-3.8 at 22℃
CAS DataBase Reference	305-84-0(CAS DataBase Reference)
EPA Substance Registry System	L-Histidine, .beta.-alanyl- (305-84-0)

Safety Information

Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	24/25-36-26
WGK Germany	2
RTECS	MS3080000
F	3-10
TSCA	TSCA listed
HS Code	29332900
Storage Class	11 - Combustible Solids
Toxicity	LD50 oral in mouse: > 14930mg/kg

MSDS Information

Provider	Language
L-Carnosine	English
SigmaAldrich	English
ACROS	English

L-Carnosine Usage And Synthesis

Description	L-Carnosine is a dipeptide composed of β-alanine and L-histidine that has been found in rat olfactory bulb, skeletal muscle, brain, kidney, and spleen tissues, as well as human skeletal muscle, and has diverse biological activities. It is a metal chelator that forms complexes with copper, cobalt, nickel, cadmium, or zinc. Dietary administration of L-carnosine (60 mg/kg per day) reduces plasma levels of advanced glycation end products (AGEs) in diabetic rats. It reduces brain edema, blood-brain barrier disruption, microglial activation, and neuronal apoptosis in a rat model of intracerebral hemorrhage when administered at a dose of 1,000 mg/kg. L-Carnosine (250, 500, and 1,000 mg/kg, i.p.) reduces hepatic protein carbonylation and necrosis in a rat model of cirrhosis induced by bile duct ligation. It also reduces lung myeloperoxidase (MPO) activity, production of reactive oxygen species (ROS), and TNF-α and IL-6 levels, as well as alveolar hemorrhage, interstitial edema, and pulmonary leukocyte infiltration in a mouse model of LPS-induced lung injury.
Chemical Properties	white to off-white crystalline.
History	Carnosine, a dipeptide composed of beta-alanine and L-histidine, was first identified in beef extracts by Russian chemists Gulewitch and Amiradzibi in 1900.
Uses	L-Carnosine is a naturally-occurring histidine-containing compound and the biological role of this dipeptide is to act as cytosolic buffering agents. Other roles ascribed to L-Carnosine include action s as neurotransmitters, modulation of enzymic activities and chelation of heavy metals. Studies indicate an ability to boost the immunological functions. In cosmetics, it has anti-aging and skin-conditioning applications.
Definition	ChEBI: Carnosine is a dipeptide that is the N-(beta-alanyl) derivative of L-histidine. It has a role as an anticonvulsant, an antioxidant, an antineoplastic agent, a human metabolite, a Daphnia magna metabolite, a mouse metabolite, a neuroprotective agent and a geroprotector. It is a conjugate acid of a carnosinate. It is a tautomer of a carnosine zwitterion.
Application	L-Carnosine has been used to study its effects as an antioxidant on meat quality of pigs. It has also been used to study its effects on brain injury in a rat intracerebral hemorrhage model.
benefits	L-Carnosine is a strong anti-glycosylation, free radical scavenging,anti-oxidant,anti-aging, anti-pollution.Brightenand repairthe skin. white powder.Its recommended dosage is 0.05~2%.

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Crystalline

Basic Info

Product Name:

L-Carnosine

Other Name:

N-B-ALANYL-L-HISTIDINE;H-BETA-ALA-HIS-OH;L-IGNOTINE;L-BETA-ALANINE HISTIDINE;L-CARNOSINE;B-ALANYL-L-HISTIDINE;BETA-A-H;BETA-ALANYL-L-HISTIDINE

CAS No.:

305-84-0

Molecular Formula:

C9H14N4O3

InChIKeys:

CQOVPNPJLQNMDC-ZETCQYMHSA-N

Molecular Weight:

226.23

Exact Mass:

226.23

BRN:

87671

EC Number:

206-169-9

UNII:

8HO6PVN24W

TSCA:

TSCA listed

DSSTox ID:

DTXSID7048615

NCI Thesaurus Code:

C118880

Color/Form:

White

HScode:

29332900

Categories:

Vitamins and Minerals Medicines

Characteristics

PSA:

121

XLogP3:

-4

Appearance:

White crystalline

Density:

1.2673 (rough estimate)

Melting Point:

253 °C (dec.) (lit.)

Boiling Point:

367.84°C (rough estimate)

Flash Point:

350.7ºC

Refractive Index:

21 ° (C=2, H2O)

Water Solubility:

almost transparency

Storage Conditions:

2-8°C

Vapor Pressure:

0Pa at 25℃

Toxicity:

LD50 oral in mouse: > 14930mg/kg

Flammability characteristics:

Thermal decomposition to emit toxic nitrogen oxide fumes

Specific rotation:

20.9 º (c=1.5, H2O)

Odor:

at 100.00%. odorless

PKA:

2.62(at 25℃)

Collision Cross Section:

151 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|149.72 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|152.18 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|154.1 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|154.93 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|150.8 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|154.7 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|152.1 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|153.1 Å² [M-H]-

Critical Temperature & Pressure:

-20°C

See More L-Carnosine Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More L-Carnosine Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

42 Inquiries

Country	Product	Purchase Quantity	Date Posted
Russia	L-Carnosine CAS 305-84-0	50 KG	Jan 13, 2026
India	L-Carnosine	20.00 MT	Dec 13, 2023
India	L-Carnosine	10.00 KG	Dec 12, 2023
India	L-Carnosine	1.00 KG	Oct 11, 2025
India	L-Carnosine	10.00 MT	Dec 15, 2023
India	L-Carnosine	20.00 MT	Dec 13, 2023
Australia	L-Carnosine	1000 G	Aug 4, 2026
India	L-Carnosine	1 KG	Aug 4, 2026
India	L-Carnosine	100 KG	Jul 10, 2026
India	L-Carnosine	25.00 KG	Jun 29, 2026
India	L-Carnosine	1.00 KG	Jun 4, 2026
India	L-Carnosine	1.00 KG	May 28, 2026
India	L-Carnosine	25.00 KG	Mar 9, 2026
India	L- Carnosine	150.00 KG	Jan 21, 2026
India	L-Carnosine	500.00 KG	May 30, 2025
Australia	L-Carnosine	1 KG	Sep 30, 2024
Russia	carnosine L	100 KG	Mar 11, 2024
Hungary	L-Carnosine	1 KG	Jul 6, 2026
Netherlands	L-Carnosine	15 KG	Jun 24, 2026
India	L-Carnosine	1.00 KG	May 28, 2026

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