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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Megestrol acetate for Sale > Super high quality ACE AE1 99% white powder China Fast Delivery
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Super high quality ACE AE1 99% white powder China Fast Delivery

TDS 1 Inquiries

Unit Price:

$5-6/UNIT FOB

Get Latest Price
CAS No.:

595-33-5

Grade:

Pharmaceutical Grade

Content:

99.87%

Port:

hongkong

Brand:

Customization Available

Packaging:

1mg*10vials/box

Price valid (until):

2026-09-24

Company Type:
Trader
Location:
China
Payment Terms:
100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Retatrutide,Tirzepatide,GLOW,KLOW80,NAD+,TB500

  • Product Description

  • Seller Information

  • History Price

  • Inquiry History

  • Description


        Ⅰ. Business Manager Contact Details    


    Name: Anna

    Email address : xiaobo19872026@outlook.com

    Whatsapp : +85244588108

                         +8613180089301

    Telegram : @anna20260512


       Ⅱ. Product Overview   


    ACE acts as a soluble decoy receptor and binds to ligands such as myostatin and activin, which inhibit muscle growth, in the blood. It prevents these ligands from binding to the ActRIIB receptors on human cells, thereby releasing the inhibitory signals for muscle growth.

    Efficacy

    1. Increase lean muscle mass: In the Phase I human trial, after a single high-dose administration, the total lean body weight and thigh muscle volume of the subjects showed statistically significant increases.
    2. Improve bone metabolism indicators: In the study, some bone metabolism biomarkers showed positive changes, suggesting potential effects on the bones.
    3. Research target indication direction: The main research focuses on models of muscle wasting diseases such as Duchenne muscular dystrophy (DMD), muscle atrophy, and age-related muscle attenuation.

    Shop Super high quality ACE AE1 99% white powder China Fast Delivery-Detailed Image 1 Shop Super high quality ACE AE1 99% white powder China Fast Delivery-Detailed Image 2



         Ⅲ. Company Overview   


    Our company is a modern and advanced enterprise, specializing in the production and export of raw materials for drugs, drug intermediates, and plant extracts. Our products are widely used in the fields of medicine, medical health products, cosmetics, nutritional supplements, and food additives.

    Shop Super high quality ACE AE1 99% white powder China Fast Delivery-Detailed Image 3

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         Ⅳ. Logistics and Transport    


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    Shop Super high quality ACE AE1 99% white powder China Fast Delivery-Detailed Image 9



         Ⅴ. What are peptides?   


    Peptide products offer diverse functional benefits across multiple scenarios:

    1. In health management, peptides support metabolic regulation (aiding in blood sugar control and healthy weight management for specific groups) and immune system modulation by enhancing the body's defense responses; 

    2. In skincare, peptides promote skin barrier repair, boost collagen synthesis to reduce fine lines, and improve skin hydration and elasticity; 

    3. In sports nutrition, peptides assist in muscle recovery by reducing post-exercise tissue damage and supporting muscle protein synthesis.

    Shop Super high quality ACE AE1 99% white powder China Fast Delivery-Detailed Image 10



       Ⅵ. Customizable peptide   


    1. 1. Skin care peptide
    2. 2. Beauty peptide
    3. 3. Muscle building peptide
    4. 4. Hair growth peptide
    5. 5. Weight loss peptide
    6. 6. Fitness peptide

    Shop Super high quality ACE AE1 99% white powder China Fast Delivery-Detailed Image 11



        Ⅶ. FAQ   


    Q1: About the after-sale service

    A: After purchasing the products from our Lab, we have A professional technical team and after-sales team to serve you and solve all your problems in the future.


    Q2: Do you have stock?

    A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.


    Q3: How do I start paying?

    You can pay via Bitcoin, bank transfer, USDT or PayPal.


    Q4: How to confirm product quality before placing an order?

    A: We got good feedback from customers and Tested by third-party institutions. You also can get free samples of some products. You just have to pay the shipping fee for the sample.

    You can send us your product specifications and requirements and we can customize for you.


    Q5: What is your MOQ?

    A: The minimum quantity we can order is 1 box.

    But usually we can accept a smaller quantity, say 100g, at the cost of 100% sample charge.


    Q6: Time for delivery?

    A: Leading time within 3 business days,Shipping time about 8-10 business days. 


    Q7: Why should I choose you?

    A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5years, in average.Strict quality control-comes form our sophisticated management system.Professional and warm sales team-since we believe we can only win via our hard work in a competitive world.Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service.


       Ⅷ. Basic Info   


    Items Specifications
    Product Name ACE031
    Specification 1mg
    Purity >99%
    Storage Conditions -20℃
    ECHEMI Editorial Reference
    Megestrol Acetate is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HegG2.Target: Progesterone ReceptorMegestrol acetate, also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, and sometimes abbreviated as MGA or MA, is a steroidal progestin and progesterone derivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropic effects. Megestrol acetate is a good candidate for muscle wasting treatment and future
    Megestrol acetate is a steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid. It is an appetite stimulant used for the treatment of anorexia and cachexia. Also used for birth control and for the treatment of breast cancer. It has a role as an antineoplastic agent, an appetite enhancer, a contraceptive drug, a progestin and a synthetic oral contraceptive. It is a steroid ester, an acetate ester, a 20-oxo steroid and a 3-oxo-Delta(4) steroid. It derives from a megestrol.|17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.|Megestrol Acetate is the acetate salt form of megestrol, a synthetic derivative of the naturally occurring female sex hormone progesterone with potential anti-estrogenic and antineoplastic activity. Mimicking the action of progesterone, megestrol acetate binds to and activates nuclear progesterone receptors in the reproductive system, and causes the ligand-receptor complex to be translocated to the nucleus where it binds to and promotes expression of target genes. This leads to an alteration in protein synthesis, which modulates cell growth of reproductive tissues. Due to the negative feedback mechanism seen with progesterone, megestrol also blocks luteinizing hormone (LH) release from the pituitary gland, thereby leading to an inhibition of ovulation and an alteration in the cervical mucus and endometrium. Furthermore, without stimulation of LH, estrogen release from the ovaries is stopped, hence impedes the growth of estrogen-sensitive tumor cells.|Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia. (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)

    Certificates
    • Super high quality ACE AE1 99% white powder China Fast Delivery Certificates 1 TDS

    Basic Info
    Product Name:

    Megestrol acetate

    Other Name:

    Pregna-4,6-diene-3,20-dione,17-(acetyloxy)-6-methyl-;Pregna-4,6-diene-3,20-dione,17-hydroxy-6-methyl-,acetate;17-(Acetyloxy)-6-methylpregna-4,6-diene-3,20-dione;BDH 1298;5071;SC 10363;17α-Acetoxy-6-dehydro-6-methylprogesterone;DMAP;17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate;Megestrol acetate;6-Methyl-6-dehydro-17α-acetoxyprogesterone;6-Methyl-17α-hydroxy-Δ6-progesterone acetate;17α-Acetoxy-6-methylpregna-4,6-diene-3,20-dione;6-Dehydro-6-methyl-17α-acetoxyprogesterone;6-Methyl-17α-acetoxy-4,6-pregnadiene-3,20-dione;17-Acetoxy-6-methylpregna-4,6-diene-3,20-dione;17α-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate;6-Methyl-Δ4,6-pregnadien-17α-ol-3,20-dione acetate;Megace;Niagestin;Megestryl acetate;Magestin;Megeron;Ovarid;MGA;Megestin;Nia;Megestat;Maygace;Megestil;Ovaban;NSC 71423;Megalia

    CAS No.:

    595-33-5

    Molecular Formula:

    C24H32O4

    InChIKeys:

    InChIKey=RQZAXGRLVPAYTJ-GQFGMJRRSA-N

    Molecular Weight:

    384.51

    Exact Mass:

    384.51

    EC Number:

    209-864-5

    UNII:

    TJ2M0FR8ES

    NSC Number:

    71423

    DSSTox ID:

    DTXSID9040683

    NCI Thesaurus Code:

    C1156

    HScode:

    29372390

    Characteristics
    PSA:

    60.4

    XLogP3:

    3.2

    Appearance:

    Crystalline Solid

    Density:

    1.2±0.1 g/cm3

    Melting Point:

    214 °C

    Boiling Point:

    431.17°C (rough estimate)

    Flash Point:

    218.5±30.2 °C

    Refractive Index:

    1.551

    Water Solubility:

    2 µg/mL (at 37 °C for the acetate salt)

    Storage Conditions:

    Refrigerator

    Toxicity:

    LD50 intravenous in mouse: 56mg/kg

    Specific rotation:

    D24 +5° (chloroform)

    Collision Cross Section:

    180.1 Ų [M+H-H2O]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Research
    Class:

    Actin-sequestering protein / 43-amino-acid peptide

    Status:

    Research compound — Not FDA approved (investigational: RGN-259 for dry eye / neurotrophic keratitis)

    Mechanism:

    A naturally occurring 43-amino-acid peptide (Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH) that binds G-actin (sequesters monomeric actin), preventing F-actin polymerization. Promotes cell migration, angiogenesis, wound healing, and anti-inflammatory responses via integrin-linked kinase (ILK) and HIF-1α/VEGF pathways. TB-500 is the synthetic fragment Ac-LKKTETQ (MW ~895) often sold under this CAS.

    Activity note:

    Thymosin Beta-4 is an actin-binding protein, not a receptor agonist. Functional activity is measured by actin sequestration (Kd ~0.7–1 μM) and cell migration assays, not EC₅₀.

    Source:

    Goldstein AL, et al. Vitam Horm. 2003;66:257–296. RegeneRx RGN-259 clinical program.DOI

    Clinical Development:

    NCT02974907; NCT02600429; NCT00376974

    References
    DrugBank:

    DB04951

    PubChem:

    PubChem

    UNII:

    549LM7U24W

    Disclaimer:

    Thymosin Beta-4 (TB-500) is NOT FDA-approved for human therapeutic use. RGN-259 (Tβ4 ophthalmic solution) is an investigational drug not yet approved. TB-500 sold on research-chemical marketplaces is a synthetic fragment and is not an approved medicine. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

    Hazard Identification

    Classification of the substance or mixture

    Carcinogenicity, Category 2

    Specific target organ toxicity – repeated exposure, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H351 Suspected of causing cancer

    H373 May cause damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    Response

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Retatrutide,Tirzepatide,GLOW,KLOW80,NAD+,TB500

    Location:

    Room 11B, Building 0056, No. 81-1 Nonglinxia Road, Yuexiu District, Guangzhou City, Guangdong Province

    Payment Terms:

    100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2026

    Company Profile

    Our company is a modern and advanced enterprise, specializing in the production and export of raw materials for drugs, drug intermediates, and plant extracts. Our products are widely used in the fields of medicine, medical health products, cosmetics, nutritional supplements, and food additives. Our factory covers an area of 95 acres. The proposed factory will comply with GMP standards. The factory environment is clean and tidy, with a reasonable layout, and includes large and medium-sized production workshops as well as shared workshops. It is equipped with advanced equipment, quality inspection and research centers. These products have reached the advanced domestic level in terms of quality and technical content. Since its establishment, the company has attached great importance to team training and technological reform. Our modern production equipment ensures the rapid and efficient production of the entire line, with high precision. All processing, extraction, packaging and transportation are completed internally, ensuring the highest quality and efficiency. We continuously develop new ingredients and innovative products, earning respect and praise from global customers. After years of continuous development, the company has accumulated rich experience in international trade and customer resources, established a stable customer base and a complete marketing service network. In addition, the company has established long-term technical cooperation relationships with experts and professors from many universities and research institutions in the province.

  • Weekly Price

    The chart shows the price trend of the product in the past 12 months.

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    Megestrol acetate

    15 KG Mar 12, 2024
    Post an enquiry for this product
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