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Semaglutide 99% 910463-68-2 Pharmaceutical Grade 2/5/10/15/20/30mg/vials 10vials/box lyophilized powder Dissolved in dimethyl sulfoxide buy - image1

Semaglutide 99% 910463-68-2 Pharmaceutical Grade 2/5/10/15/20/30mg/vials 10vials/box lyophilized powder Dissolved in dimethyl sulfoxide

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Unit Price:

$10/G FOB

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CAS No.:

910463-68-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

qingdao

Brand:

HKX

Packaging:

2/5/10/15/20/30mg/vials 10vials/box

Sample Available:

Yes

Price valid (until):

2027-01-31

Contact Supplier

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HuaKeXin

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

12 days

Qualification:

Main Products:

Tirzepatide,Semaglutide,Retatrutide,MOTS-C,GHK-CU,MT-2

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Product Details
Seller Information
History Price
Inquiry History

Description

Product Detail

Items	Specifications
Name	Semaglutide
CAS RN	910463-68-2
Solubility	Dissolved in dimethyl sulfoxide
Storage condition	-20°C

Shop Semaglutide 99% 910463-68-2 Pharmaceutical Grade 2/5/10/15/20/30mg/vials 10vials/box lyophilized powder Dissolved in dimethyl sulfoxide-Detailed Image 1

2. Product Standard Specifications

Product Full Name: Semaglutide

CAS Registry Number: 910463-68-2

Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉

Molecular Weight: 4113.57754

Complete Amino Acid Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-Cys)-Gly-Ser-Asn-Gly-Pro-Val-Val-Gly-Ala-Pro-Pro-Pro-Ser-NH₂

Physical Appearance: Pure White Crystalline Powder

Total Purity (HPLC Test): ≥99.0%

English Translation: This purity is determined by Reversed-Phase High Performance Liquid Chromatography (RP-HPLC). It meets and exceeds the standard of no less than 98% purity for pharmaceutical-grade polypeptides stipulated in national standards. At present, a variety of polypeptide products including Latromotide, Bid BH3 (80-99) and FAM labeled polypeptides have reached this purity level.

Maximum Single Impurity (HPLC): ≤1.0%

Moisture Content (Karl Fischer Method, in accordance with GB/T 6283-2008): ≤10.0%

Effective Peptide Content: ≥80.0% (Test Standard: GB/T22492-2008)

Solubility Characteristic: 3mg/mL (0.73 mM) in DMSO, clear and transparent dissolution without precipitation

Professional Storage Condition: Store at a constant temperature of -20℃, in a dry, cool and sealed environment, and avoid direct sunlight, high temperature and humidity

3. Product Overview & Industry Status

Semaglutide is a globally recognized top-tier GLP-1 (Glucagon-Like Peptide-1) receptor agonist peptide raw material, occupying a core leading position in the global metabolic regulation and weight management raw material market. In 2024, the combined sales revenue of its three formulations reached approximately 29.296 billion US dollars, accounting for nearly 70% of Novo Nordisk's total revenue, and it was only less than 200 million US dollars away from being the world's top-selling drug. Novo Nordisk, relying on semaglutide, holds 91% of the global obesity drug market share and 56.0% of the global GLP-1 diabetes drug market share. In recent years, with the rising global demand in the field of chronic metabolic health management, Semaglutide has become one of the most popular and highly recognized peptide products in the international biotech raw material industry.

Compared with traditional metabolic regulation raw materials, Semaglutide features stable molecular structure, high biological activity, high absorption rate and durable efficacy.

Semaglutide has passed multiple laboratory tests complying with international standards and is backed by sufficient clinical verification data, featuring stable quality and reliable effects. A host of international multi-center clinical trials have proven its efficacy and safety, such as the SOUL study covering 444 centers across 33 countries and regions with 9650 enrolled patients, and the SELECT trial involving 17604 participants. Meanwhile, the phase 3 SUSTAIN and PIONEER studies indicated that its weekly preparation can lower glycated hemoglobin by up to 1.8% and reduce body weight by up to 6.5 kg, while the tablet form can cut glycated hemoglobin by up to 1.6% and help users lose 5.0 kg in weight, which further validates its quality and performance.

It is widely purchased and recognized by biotech laboratories, pharmaceutical research institutions, health product manufacturers and raw material distributors in Europe, America, Southeast Asia and other regions, owning extremely high market reputation and industry popularity.

4. Core Product Mechanism & Comprehensive Efficacy

As a long-acting GLP-1 receptor agonist belonging to the incretin mimetic category, Semaglutide shares a highly similar chemical structure with endogenous GLP-1 secreted by human intestines. It binds to specific receptors on cell membranes to mimic the physiological functions of GLP-1, including regulating insulin secretion, suppressing glucagon secretion, slowing gastric emptying and curbing appetite. Relevant researches prove its excellent performance in blood sugar control and weight management. In a randomized study on obese patients without type 2 diabetes, participants using high-dose Semaglutide achieved an average weight loss of 13.8%, and 65% of them lost at least 10% of their body weight.

It precisely targets and regulates human glucose and lipid metabolic pathways, achieving multi-dimensional optimization of bodily functions.

In terms of blood glucose regulation, this product acts as a GLP-1 receptor agonist, which can enhance insulin secretion in a glucose concentration-dependent manner when blood glucose level rises, while inhibiting glucagon secretion. It can effectively inhibit excessive blood glucose fluctuation, accelerate blood glucose decomposition and utilization, and maintain long-term stable blood glucose. Clinical trials involving Chinese type 2 diabetes patients have shown that similar GLP-1 receptor agonists can reduce HbA1c by 0.8%, and their efficacy is comparable to that of glimepiride, which helps address abnormal glucose metabolism.

In terms of weight management and metabolic improvement, Semaglutide can effectively slow gastrointestinal emptying, significantly reduce appetite and excessive calorie intake, and inhibit excessive fat accumulation in the body.

A number of authoritative clinical trials have fully verified its stable and prominent weight control effect. In the STEP series of trials, patients receiving Semaglutide for 68 weeks lost 17% to 18% of their initial body weight on average. In the ESSENCE study, participants in the Semaglutide group saw an average weight drop of 10.5%. The STEP 9 trial showed that after 68 weeks of use, the average weight of the treatment group decreased by 13.7% compared with the baseline. Besides, 85.2% of participants lost no less than 5% of their body weight and 68.1% lost at least 10%, far exceeding the performance of the placebo group.

It effectively addresses overweight and obesity stemming from metabolic disorders.

Different from simple lifestyle adjustment and physical exercise intervention, Semaglutide fundamentally regulates chronic metabolic disorders, corrects unbalanced lipid and glucose metabolism, and avoids rebound problems caused by single intervention methods. Clinical trials have shown that Semaglutide can reduce body weight by about 15%, and a 68-week phase 3a OASIS 1 trial found that adults taking 50mg oral Semaglutide lost 17.4% of their body weight, while the placebo group only lost 1.8%. A groundbreaking study published in Nature Medicine also used large-scale proteomic analysis to reveal its regulatory mechanisms in glucose and lipid metabolism, further confirming its advantages over single intervention methods. It serves as a professional, efficient raw material for long-term metabolic health management.

5.Our Trade Advantages & Cooperation Terms

We operate as direct source manufacturer, so we can set competitive unit price and maintain continuous stock to support both small trial orders and large bulk purchase. Every production batch is inspected with full lab tests, and complete COA document will be attached for buyers’ checking and customs clearance.

Customized label and private packaging service are available to match clients’ brand demands. For shipment, small lots are delivered via DHL, FedEx or other international courier, with goods arriving within 5~7 working days after dispatch. Sea transport is the cost-effective choice for big quantity cargo, which normally takes 15~30 working days to reach destination port depending on specific location.

Multiple payment options including T/T, bank transfer and PayPal are ready for your pick. Sample service is accessible; regular items can supply free samples while high-value goods only need customers to cover freight cost, and favorable sample policy can be discussed for long-term cooperative partners.

6. Customer FAQ

Q1: Can customers get free samples for quality testing before bulk cooperation?

A1: Yes, we provide professional sample support service for customers to conduct quality testing before bulk cooperation. Our products and services are available for global clients. For conventional peptide products, we offer free test samples, with buyers only responsible for international freight fees. For high-value, high-purity peptide raw materials, buyers only need to cover a small amount of sample cost and freight fees. Long-term cooperative clients and VIP customers are entitled to our permanent free sample policy and priority delivery service.

Q2: What international payment methods are supported by the company?

A2: We support diversified and safe international payment methods, including commonly used options like credit card payments with SSL encryption and 3D Secure verification, e-wallets with multiple encryption technologies, as well as letter of credit, collection and remittance methods. We support various international settlement methods, including T/T (telegraphic transfer), global bank transfer, PayPal and other mainstream payment channels. Clients can select the most flexible and convenient payment method based on their actual needs.

Q3: What is the logistics mode and delivery cycle after payment confirmation?

A3: For small-batch sample orders and trial orders, we adopt DHL, FedEx, TNT and other mainstream international express or air freight delivery. These express services have fast timeliness: DHL, FedEx and TNT generally deliver within 2-4 working days, with DHL taking only 2 working days to Southeast Asia and 3 working days to Europe, FedEx having competitive prices in Central and South America and Europe, and TNT providing efficient services covering more than 200 countries and regions. Besides, for small-batch orders under 21KG, they are charged according to the first weight and additional weight, with the billing unit of 0.5KG, and if the goods are less than 1KG, they are charged as 1KG. Goods can be received within 5-7 working days after shipment. For large-batch bulk orders and mass procurement, sea freight is adopted for cost-effective transportation. The delivery cycle to the destination port varies depending on the customer’s local port location and international logistics schedule: for example, if the destination is the US West Coast ports like the Port of Long Beach and the Port of Los Angeles, the sea voyage takes about 13-16 days via direct fast ship service, or 30-40 days via economical slow ship service; if the destination is the US East Coast ports such as New York Port and Savannah Port, the sea voyage takes about 25-28 days via transoceanic direct route, or about 40-60 days via the scheme of transferring at West Coast ports plus inland transportation. The above time does not include the time for cargo collection at the loading port, customs clearance at the destination port, container pickup and end delivery.

Q4: Is private customized packaging and label service acceptable?

A4: Yes, we provide one-stop personalized customization services. According to customers’ brand demands and customized requirements, we can provide exclusive private label printing, customized packaging boxes, packaging bags and other tailored solutions to satisfy your differentiated brand operation needs.

7.Company Profile

Our firm has devoted to chemical raw materials, fine chemicals and relevant accessories import and export business for years. Supported by complete supply chain layout and strict QC specifications, we integrate superior production resources and cover various product ranges sold well in domestic and overseas markets.

Sticking to the operation principle of integrity, quality supremacy and mutual benefit, we strictly manage product quality and delivery schedule. We supply all-in-one foreign trade service including product selection, logistics arrangement and customs clearance as required. Relying on abundant industry experience and mature overseas sales network, we keep catering to diversified global procurement demands and aim to build durable trustworthy trade links with worldwide customers.

Q&A

Q: When can I receive the package?

A: It will be shipped as soon as possible after payment, and the shipping time is generally 7 to 15 days.

Q: What is the minimum amount I can order?

A: The minimum quantity we can order is 1 box, which contains 10 vials.

Q:How about the price? Can you make it cheaper?

A:We always take the customer's benefit as the top priority. Price is negotiable under different conditions, we are assuring you to get the most competitive price.

Q: How do i keep the peptides when i receive it ?

A: Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2°C - 8°C. For long-term storage, peptides should be stored in the form of lyophilized powder store at -20°C or -80°C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent.

Company Profile

HKX is a reliable manufacturer and exporter of peptide raw materials.

We have strong R&D capabilities and advanced production facilities. Our products cover various synthetic peptides and related raw materials, which are widely used in scientific research and pharmaceutical development. Every batch of goods undergoes rigorous laboratory testing to meet international quality standards.

We have years of international trade experience and a complete logistics system. Neutral packaging is used for all goods to comply with international shipping regulations. We provide flexible order solutions for customers, from small trial orders to large bulk purchases.

Sticking to the philosophy of Quality Priority and Customer Oriented, we sincerely welcome customers from all over the world to negotiate business and create win-win cooperation.

Why Choose Us

·Ultra-High Purity Each batch is synthesized and purified to >99% purity (HPLC), ensuring reliable and reproducible results in sensitive experiments.

·Accurate Dosing & Consistency Our peptides are precisely weighed and vacuum-sealed under sterile conditions. Batch-to-batch consistency is rigorously maintained.

·Endotoxin-Free & Sterile Processing Manufactured in a cleanroom environment, our peptides are free from endotoxins, microbial contamination, and other impurities that could interfere with cell-based or in vivo studies.

·Retail and bulk orders are accepted.

·Neutral packaging with full sealing for safe international shipping.

·Fast dispatch within 1-3 working days after payment confirmation.

Please contact us if you have any doubts regarding our products or enterprise.

We provide dedicated service for all clients.

ECHEMI Editorial Reference

Semaglutide (CAS: 910463‑68‑2) is a synthetic lipid‑modified peptide analogue, consisting of a 31‑amino‑acid backbone with a covalently attached C18 fatty di‑acid side‑chain via a hydrophilic spacer. It shares 94% amino‑acid sequence homology with native human GLP‑1 peptide. The substance appears as white to almost white hygroscopic powder, with molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and molecular weight of 4113.58 g/mol. Structural modifications grant it resistance against DPP‑4 enzymatic degradation and enable reversible binding to serum albumin, contributing to its extended in‑vivo half‑life property.

Certificates

Basic Info

Product Name:

Semaglutide

Other Name:

Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide

CAS No.:

910463-68-2

Molecular Formula:

C187H291N45O59

InChIKeys:

DLSWIYLPEUIQAV-CCUURXOWSA-N

Molecular Weight:

4113.57754

Exact Mass:

4113.122087 g/mol

EC Number:

203-405-2

Color/Form:

White to off-white

Categories:

Polypeptide

Characteristics

PSA:

1650 Å²

XLogP3:

5.44520

Critical Temperature & Pressure:

Store at -20°C

Research

Class:

GLP-1R agonist

Status:

FDA-approved (Ozempic / Wegovy / Rybelsus)

Mechanism:

Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

Activity note:

Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

Source:

Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

Clinical Development:

NCT03548935; NCT03552757; NCT01720446; NCT02692716

FDA:

Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)

Disclaimer:

Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

See More Semaglutide Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H361 Suspected of damaging fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Semaglutide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Tirzepatide,Semaglutide,Retatrutide,MOTS-C,GHK-CU,MT-2

Location:
203, NO. 88 Zhongxin North Road, Hangzhou Avenue Sub-district, Binhai New Area, Tianjin

Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
12 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2026

Our company is a professional enterprise engaged in the chemical industry for many years, specializing in the import and export of chemical raw materials, fine chemicals, industrial additives, and related products.

With a well-established supply chain system and strict quality control standards, we integrate high-quality manufacturing resources to ensure stable product quality and reliable supply. Our product portfolio covers general chemicals, fine chemicals, rubber and plastic raw materials, water treatment chemicals, and other related categories, serving both domestic and international markets.

Adhering to the principles of integrity, quality first, and mutual benefit, we strictly control product quality and delivery timelines. We provide comprehensive one-stop foreign trade solutions, including product sourcing, customized selection, logistics coordination, and customs clearance services according to customer requirements.

Leveraging extensive industry experience and a well-developed global sales network, we are committed to meeting diverse international procurement needs. We aim to build a stable and trustworthy bridge for global chemical trade and establish long-term, sustainable partnerships with clients worldwide.
Weekly Price

 The chart shows the price trend of the product in the past 12 months.

Inquiry History

427 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Weight Loss Semaglutide intermediate 99% White powder COA High Quality peptide GLP-1 910463-68-2	5 MG	Apr 11, 2024
United States	Gene-Biocon Semaglutide 910463-68-2 GLP-1analogs diabetes weight loss 96% White or off-white powder	2	Dec 5, 2023
China	Semaglutide CAS 910463-68-2	1 KG	Apr 16, 2026
United Kingdom	TGYFactory Supply Semaglutide Peptide 99% CAS 910463-68-2	50 MT	Nov 13, 2023
Sri Lanka	Bulk Supply 98% up Sermaglutide powder CAS 910463-68-2	300 G	Nov 18, 2023
China	Semaglutide Tirzepatide for Weight Loss CAS: 910463-68-2 Retatrutide Cagrilintide	1 MT	Jul 5, 2025
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	60 MG	Aug 4, 2025
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	10 MT	Sep 19, 2025
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	2	Nov 13, 2024
United States	semaglutide CAS 910463-68-2 in stock 2-4 days safe delivery	1 MT	Nov 4, 2023
India	Best Price 99% Semaglutide Peptide 10mg Vials Semaglutide CAS 910463-68-2	100	Nov 8, 2023
United Kingdom	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	10 MT	Nov 14, 2023
Singapore	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	2 G	Nov 3, 2023
United States	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	100 MT	Oct 26, 2023
United States	99.9% Purity Semaglutide Petide 910463-68-2 For Type II diabetes mellitus Obesity	50 MT	Nov 11, 2023
United States	GLP-1 Injection Weight Loss Tirzepatide Semaglutide 99% Purity Peptides CAS: 910463-68-2	1 MT	Oct 25, 2023
United States	Manufacturer Supply Weigh Loss Peptide Semaglutide 98% with Best Price CAS 910463-68-2	1	Dec 15, 2023
United Kingdom	Weight Loss GLP-1 Peptides Purity 99% Wholesales Price 2mg 5mg 10mg Semaglutide CAS: 910463-68-2	400	Nov 13, 2023
United Kingdom	l Weight Loss Semaglutide Tirzepatide Epitalon Retatrutide pharma Peptides Liraglutide CAS: 910463-68-2 Retatrutide CAS 2381089-83-2 Ly34379	20 MT	Nov 13, 2023
Canada	Semaglutide	1 G	Jun 24, 2024

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Semaglutide 99% 910463-68-2 Pharmaceutical Grade 2/5/10/15/20/30mg/vials 10vials/box lyophilized powder Dissolved in dimethyl sulfoxide

Product Details

Seller Information

History Price

Inquiry History

Name

Semaglutide

CAS RN

910463-68-2

Solubility

Dissolved in dimethyl sulfoxide

Storage condition

-20°C

2. Product Standard Specifications

4. Core Product Mechanism & Comprehensive Efficacy

5.Our Trade Advantages & Cooperation Terms

6. Customer FAQ

Q1: Can customers get free samples for quality testing before bulk cooperation?

Q2: What international payment methods are supported by the company?

Q3: What is the logistics mode and delivery cycle after payment confirmation?

Q4: Is private customized packaging and label service acceptable?

7.Company Profile

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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