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Hot Selling Rosmarinic Acid 98% Purity Rosemary Leaf Extract Wholesales Price

TDS 7 Inquiries

Unit Price:

$10.3/KG FOB

Get Latest Price
CAS No.:

20283-92-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

ONERBIO

Packaging:

25kg/drum

Price valid (until):

2026-12-31

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

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    Product Name: Rosmarinic Acid
    CAS Number: 20283-92-5
    Molecular Formula: C₁₈H₁₆O₈
    Molecular Weight: 360.31 g/mol
    Appearance: White to off-white crystalline powder catechol


    Rosmarinic acid is a naturally occurring polyphenolic ester composed of caffeic acid and 3,4-dihydroxyphenyllactic acid. It appears as a white to off-white crystalline powder with a faint characteristic odor. It is soluble in aqueous media and polar organic solvents, and practically insoluble in nonpolar solvents. The compound is found in various plants, including rosemary, sage, basil, mint, and lemon balm, and contributes to their antioxidant properties. Its molecular structure contains two moieties and an ester linkage, which contribute to its radical-scavenging capacity. Functionally, rosmarinic acid acts as a potent free radical scavenger and exhibits antioxidant, anti-inflammatory, antimicrobial, antiviral, and neuroprotective activities. It may also chelate metal ions and modulate signaling pathways such as NF-κB and MAPK. It is widely used in pharmaceutical, nutraceutical, cosmetic, and food applications. In cosmetics, it helps protect skin from oxidative stress and supports soothing effects. In foods, it can retard lipid oxidation and extend shelf life. In research, it is employed to study oxidative stress, inflammatory pathways, and enzyme inhibition. It is also used as a standard in analytical chemistry and is often isolated from plant extracts and purified by chromatographic methods. The compound should be stored in a cool, dry, dark place, protected from heat, moisture, and strong oxidizing agents. It is generally considered safe, but appropriate laboratory precautions are recommended.

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    ITEMS

    STANDARDS

    RESULTS

    Description

    White to almost white powder

    White powder

    UV absorbance ratio

    A250/A260

    A280/A260

    0.41-0.49

    2.03-2.71

    0.45

    2.14

    PH

    2.0-4.0

    2.68

    Loss on drying

    5.0%

    2.64%

    Assay (UV)

    98.0%

    99.17%

    Transmittance

    98.5%

    99.1%

    Heavy metals

    10ppm

    10ppm

    Purity (HPLC)

    98.0%

    99.6%

    Conclusion

    It complies to the standard


    For regulatory compliance (e.g., USP, EP, JP), raw material Vidarabine must meet several rigorous standards:

    • Assay (by HPLC): 98.0% – 102.0% on an anhydrous basis.

    • Related Substances: Limits for specific impurities, notably Ara-Hx (NMT 2.0%), as well as any unspecified individual impurity (NMT 0.1%) and total impurities (NMT 2.0%).

    • Residual Solvents: Must comply with ICH Q3C guidelines (Class 1 and 2 solvents limited or absent).

    • Heavy Metals: NMT 20 ppm (typically lower for injectable grades).

    • Water Content (Karl Fischer): NMT 6.0% (the material is hygroscopic to a degree).

    • Microbial Limits: Total aerobic microbial count (TAMC) ≤ 1000 CFU/g, absence of S. aureus, P. aeruginosa, and Candida albicans.

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    As a high-purity pharmaceutical intermediate, L-Tyrosine Ethyl Ester Hydrochloride is predominantly utilized in the chemical synthesis of bioactive peptides, dopamine analogs, and melanin precursors. Its excellent solubility profile makes it an ideal chiral building block for asymmetric synthesis and a critical substrate in enzymatic reactions. Available in purity grades of ≥98% (HPLC), it meets stringent requirements for R&D and cGMP manufacturing processes. Reliable supply ensures batch-to-batch consistency for long-term project scalability.


    Vidarabine is classified as a potential reproductive hazard and an irritant. Safety Data Sheets (SDS) mandate the following:

    • Hazard Statements (H360): May damage fertility or the unborn child (Category 1B).

    • Precautionary Measures: Use fume hoods and wear impermeable gloves (e.g., nitrile), lab coats, and safety goggles. Avoid generating airborne dust.

    • First Aid: In case of skin contact, wash immediately with copious soap and water. If inhaled, move to fresh air.

    • Storage: Store in tightly sealed, light-resistant containers at 2°C to 8°C (refrigerated) for long-term stability. Avoid freezing.


    While superseded by newer nucleoside analogs (Acyclovir, Ganciclovir) for systemic use due to better bioavailability and lower toxicity, Vidarabine retains niche value. Its primary current application is ophthalmic ointment (3%) . Pharmacokinetically, the raw material has poor oral bioavailability (<10%) and is rapidly deaminated in the gastrointestinal tract, necessitating parenteral or topical administration.


    Vidarabine API is a well-characterized, stable crystalline nucleoside analog. While its systemic use has declined, it remains a critical raw material for topical antiviral ophthalmic preparations, particularly where resistance to other agents occurs. Manufacturers must strictly control impurities (especially Ara-Hx) and water content to ensure final drug product efficacy.

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    ECHEMI Editorial Reference
    Rosmarinic acid (RA) is a widespread phenolic ester compound in the plants. Rosmarinic acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.

    Certificates

    Basic Info
    Product Name:

    Rosmarinic acid

    Other Name:

    Benzenepropanoic acid,α-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-,(αR)-;Cinnamic acid,3,4-dihydroxy-,2-ester with 3-(3,4-dihydroxyphenyl)lactic acid;Benzenepropanoic acid,α-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-,[R-(E)]-;Rosmarinic acid;Benzenepropanoic acid,α-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-,(αR)-;(αR)-α-[[(2E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxybenzenepropanoic acid;Rosemary acid;Rosemaric acid;RM 21A;Mamorekku RUH 2;Meiji Red Perilla Polyphenol;trans-Rosmarinic acid;Labiatenic acid;Labiatic acid;NPLC 0542;SYL 001

    CAS No.:

    20283-92-5

    Molecular Formula:

    C18H16O8

    InChIKeys:

    InChIKey=DOUMFZQKYFQNTF-WUTVXBCWSA-N

    Molecular Weight:

    360.31500

    Exact Mass:

    360.31

    EC Number:

    606-487-1

    HScode:

    2932999099

    Categories:

    Nutrition Supplements

    Characteristics
    PSA:

    144.52000

    XLogP3:

    2.4

    Appearance:

    Solid

    Density:

    1.547g/cm3

    Melting Point:

    169-171.5 °C

    Boiling Point:

    694.7ºC at 760 mmHg

    Flash Point:

    254.5ºC

    Refractive Index:

    1.713

    Water Solubility:

    soluble in ethanol, DMSO or dimethyl formamide to approximately 25 mg/mL

    Vapor Pressure:

    2.92E-20mmHg at 25°C

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H400 Very toxic to aquatic life

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P273 Avoid release to the environment.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

    Location:

    Changqing 5th Road, Jianghan District

    Payment Terms:

    TT against copy of documents

    Average lead Time:

    5

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2020

    Wuhan Oner Biotech Co.,Ltd. located in the popular city of Wuhan, specilize in producing and developing pharmaceutical & its intermediates, Cosmetics Raw Material and Intermediate, food additive, Plant extracts,and in distributing the products of our own company. We serves our clients by supplying high-quality.These products are manufactured in ISO 9001 certified plants and have continuously been passing quality inspection by CIQ (China Entry & Exit Inspection and Quarantine Bureau),100% pass rate. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , the products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

  • Inquiry History
    7 Inquiries
    Country Product Purchase Quantity Date Posted
    Argentina

    rosmarinic acid

    1 G Jan 7, 2026
    United Kingdom

    Rosmarinic acid

    1 KG Jun 29, 2025
    Italy

    Rosmarinic acid

    200 KG Jun 22, 2024
    New Zealand

    Rosmarinic acid

    250 G Jan 29, 2026
    India

    Rosmarinic acid

    1 KG Jan 7, 2026
    South Korea

    Rosmarinic acid 99%

    100 G Aug 5, 2025
    Hungary

    Rosmarinic acid

    1 KG Nov 20, 2024
    Post an enquiry for this product
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