Improve Longevity Protein Anti-Aging Ingredients 5-Deazaflavin Powder in China

Product Name: Deazaflavin (5-Deazaflavin)
CAS Number: 26908-38-3
Molecular Formula: C₁₁H₇N₃O₂
Molecular Weight: 213.19 g/mol
Appearance: Light yellow crystalline powder

Description: Deazaflavin, specifically 5-deazaflavin, is a redox-active flavin analog in which the atom at position 5 of the isoalloxazine ring is replaced by a carbon atom. It is a yellow to orange crystalline solid that is sparingly soluble in water but soluble in polar aprotic solvents such as DMSO and DMF. The compound is stable under normal laboratory conditions but should be protected from light, moisture, and strong oxidizing agents, and stored in a cool, dry place. Functionally, deazaflavin serves as an important biochemical tool for studying flavin-dependent enzymes, electron-transfer reactions, and hydride-transfer mechanisms. Because it lacks the reactive N5 position, it cannot form covalent N5-flavin adducts, making it valuable for probing enzyme mechanisms and cofactor reactivity. It is a structural parent of the F420 cofactor found in methanogenic archaea and mycobacteria, and its derivatives are used in research on F420-dependent enzymes, antibiotic target discovery, and prodrug activation. Deazaflavin analogues also find applications as electron mediators, photosensitizers, fluorescent probes, and redox catalysts in chemical and biological systems. It is intended for research use only and should be handled with appropriate personal protective equipment.

For regulatory compliance (e.g., USP, EP, JP), raw material Vidarabine must meet several rigorous standards:

• Assay (by HPLC): 98.0% – 102.0% on an anhydrous basis.

• Related Substances: Limits for specific impurities, notably Ara-Hx (NMT 2.0%), as well as any unspecified individual impurity (NMT 0.1%) and total impurities (NMT 2.0%).

• Residual Solvents: Must comply with ICH Q3C guidelines (Class 1 and 2 solvents limited or absent).

• Heavy Metals: NMT 20 ppm (typically lower for injectable grades).

• Water Content (Karl Fischer): NMT 6.0% (the material is hygroscopic to a degree).

• Microbial Limits: Total aerobic microbial count (TAMC) ≤ 1000 CFU/g, absence of S. aureus, P. aeruginosa, and Candida albicans.