Acetohydroxamic acid RC08354
546-88-3
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2030-01-01
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceAcetohydroxamic acid is a potent and irreversible inhibitor of bacterial and plant urease and also used as adjunctive therapy in chronic urinary infection.Target: UreaseAcetohydroxamic acid selectively inhibits arachidonate 5-lipoxygenase and thus has potential use in the treatment of asthma.
Solid
Acetohydroxamic acid is a member of the class of acetohydroxamic acids that is acetamide in which one of the amino hydrogens has been replaced by a hydroxy group. It has a role as an EC 3.5.1.5 (urease) inhibitor and an algal metabolite. It derives from an acetamide. It is a tautomer of a N-hydroxyacetimidic acid.|Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.|Acetohydroxamic acid is an Urease Inhibitor. The mechanism of action of acetohydroxamic acid is as an Urease Inhibitor.Basic Info-
Product Name:
Acetohydroxamic acid
Other Name:Acetamide,N-hydroxy-;Acetohydroxamic acid;AHA;Acetohydroximic acid;Acetic acid,oxime;Hydroxylamine,N-acetyl-;Acetylhydroxamic acid;Methylhydroxamic acid;N-Hydroxyacetamide;N-Acetylhydroxylamine;Acetylhydroxylamine;NSC 176136;NSC 408425;NSC 5073;AHA (urease inhibitor);1113-25-3
CAS No.:546-88-3
Molecular Formula:C2H5NO2
InChIKeys:InChIKey=RRUDCFGSUDOHDG-UHFFFAOYSA-N
Molecular Weight:75.07
Exact Mass:75.07
BRN:1739019
EC Number:208-913-8
UNII:4RZ82L2GY5
NSC Number:755855|176136|5073
DSSTox ID:DTXSID7022546
ATC Code:G - Genito urinary system and sex hormones
HScode:2924199090
Categories:
Characteristics-
PSA:
49.3
XLogP3:-1.6
Appearance:White to pale yellow Crystalline Solid
Density:1.2±0.1 g/cm3
Melting Point:89-92 °C
Boiling Point:231.4°C at 760 mmHg
Refractive Index:1.421
Water Solubility:soluble in water.
Storage Conditions:Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Toxicity:Peritoneal-mouse LD50: 1300 mg/kg
Flammability characteristics:Flammable; decomposes by heating to release toxic nitrogen oxide fumes
PH:9.39 (aq soln)
PKA:8.7(at 25 °C)
Dissociation Constants:8.7 (at 25 °C)|pKa= 8.70
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H360 May damage fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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