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Deoxyneocryptotanshinone

Name: Deoxyneocryptotanshinone
Brand: Cuicheng Bio
SKU: pr2606081144
Price: 180000 USD
Availability: InStock

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CAS No.:

27468-20-8

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

5mg

Price valid (until):

2026-07-09

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
Seller Information

Description

Deoxyneocryptotanshinone is a naturally occurring lipophilic abietane diterpenoid isolated from the roots of the medicinal plant Salvia miltiorrhiza (commonly known as Danshen). In biochemistry and pharmacology, it functions primarily as a highly specific enzyme inhibitor used in Alzheimer’s disease research and metabolic disorder studies.

Primary Biological Functions

BACE1 (Beta-Secretase) Inhibition: It acts as a high-affinity BACE1 inhibitor with an half-maximal inhibitory concentration (IC₅₀) value of 11.53 μM. BACE1 is the essential enzyme responsible for generating amyloid-beta (Aβ) plaques in the brain. By blocking this enzyme, Deoxyneocryptotanshinone helps prevent the neurotoxic protein accumulation that drives Alzheimer's disease progression.
PTP1B (Protein Tyrosine Phosphatase 1B) Inhibition: It exhibits dose-dependent inhibition of PTP1B with an IC₅₀ value of 133.5 μM. PTP1B is a major negative regulator of insulin and leptin signaling pathways. Inhibiting this enzyme is a primary therapeutic target for treating type 2 diabetes and obesity, as it helps restore insulin sensitivity.
Broad Tanshinone Pharmacological Activity: As part of the broader family of lipophilic tanshinones, it shares basic structural traits that contribute to anti-inflammatory, antioxidant, and cardiovascular protective activities. It helps mitigate oxidative stress and inflammation, which are foundational mechanisms in both neurodegenerative and cardiovascular diseases.

Basic Info

Product Name:

5,6,7,8-Tetrahydro-3-hydroxy-2-isopropyl-8,8-dimethyl-1,4-phenanthrenedione

Other Name:

5,6,7,8-Tetrahydro-3-hydroxy-2-isopropyl-8,8-dimethyl-1,4-phenanthrenedione;Deoxyneocryptotanshinone

CAS No.:

27468-20-8

Molecular Formula:

C19H22O3

InChIKeys:

UPLOJIODCUTBOZ-UHFFFAOYSA-N

Molecular Weight:

298.37618

Exact Mass:

298.156891

Categories:

Quinone Ring

Characteristics

PSA:

54.37000

XLogP3:

5.74

Density:

1.2±0.1 g/cm3

Boiling Point:

468.0±45.0 °C at 760 mmHg

Flash Point:

251.0±25.2 °C

Refractive Index:

1.583

See More 5,6,7,8-Tetrahydro-3-hydroxy-2-isopropyl-8,8-dimethyl-1,4-phenanthrenedione Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 5,6,7,8-Tetrahydro-3-hydroxy-2-isopropyl-8,8-dimethyl-1,4-phenanthrenedione Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

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Deoxyneocryptotanshinone

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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