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Nootkatone

Unit Price: Get Latest Price
CAS No.:

4674-50-4

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

1g

Price valid (until):

2026-07-08

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

  • Product Description

  • Seller Information

  • Description
    Nootkatone is a natural sesquiterpenoid compound found primarily in grapefruit, Nootka cypress, and ginger. Its primary functions include serving as a highly effective natural insect repellent and insecticide, a premium flavoring agent in the food and fragrance industries, and a bioactive molecule that regulates energy metabolism [1.1].
    1. Core Biological and Insecticidal Functions
    • Potent Natural Insect Repellent: Nootkatone has exceptional repellent and insecticidal properties against ticks (such as the blacklegged tick that transmits Lyme disease), mosquitoes, fleas, and bedbugs [1.1]. It acts by disrupting the pest's nervous system, leading to rapid knockdown and control [1.1].
    • High Safety Profile: Due to its natural origin and low toxicity, the U.S. EPA has approved nootkatone as an active ingredient for use in skin-applied insect repellents and consumer pest control products [1.1].
    2. Commercial, Fragrance, and Food Industry Functions
    • High-Value Fragrance Component: Nootkatone is the primary molecule responsible for the characteristic aroma of grapefruit. Because of its intense citrus and grapefruit profile, it is highly valued and widely used in fine perfumery, body care products, and cosmetics.
      • Food Flavor Enhancer: In the food industry, it serves as a flavor additive in beverages, candies, baked goods, and ice creams to deliver a fresh, slightly bitter, and well-rounded citrus fruit flavor note.
      3. Cellular Metabolism and Pharmacological Functions
      • AMPK Pathway Activation: Research indicates that nootkatone is a potent activator of AMPK (AMP-activated protein kinase). It significantly accelerates cellular energy expenditure and stimulates fatty acid oxidation in muscle tissues.
      • Anti-Obesity and Anti-Diabetic Potential: In metabolic models, it effectively enhances overall energy metabolism efficiency and suppresses body fat accumulation induced by high-fat diets, demonstrating potential for improving insulin resistance and preventing obesity.
      • Anti-Inflammatory and Antioxidant Activity: It attenuates tissue inflammation by inhibiting specific pro-inflammatory cytokines (such as TNF-α and IL-6) while scavenging free radicals to protect cells from oxidative damage.


    Basic Info
    Product Name:

    NOOTKATONE

    Other Name:

    NOOTKATONE;(+)-5,6-dimethyl-8-isopropenylbicyclo[4.4.0]dec-1-en-3-one;2(3h)-naphthalenone,;2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-4,4a-dimethyl-6-(1-methylethenyl)-, [4R-(4alpha,4aalpha,6beta)]-;2(3H)-Naphthalenone,4,4a,5,6,7,8-hexahydro-4,4a-dimethyl-6-(1-methylethenyl)-,[4R-(4.alpha.,4a.alpha.,6.beta.)]-;4,4a,5,6,7,8-hexahydro-4,4a-dimethyl-6-(1-methylethenyl)-,[4R-(4.alpha.,4a.alpha.,6.beta.)]-2(3H)-Naphthalenone;NOOTKATONE 98% CRYSTALS;NOOTKATONE DISTILLED 50%

    CAS No.:

    4674-50-4

    Molecular Formula:

    C15H22O

    InChIKeys:

    WTOYNNBCKUYIKC-UHFFFAOYSA-N

    Molecular Weight:

    218.33

    Exact Mass:

    218.33

    BRN:

    4676969

    EC Number:

    225-124-4

    UNII:

    IZ2Y119N4J

    TSCA:

    TSCA listed

    DSSTox ID:

    DTXSID8047050

    Color/Form:

    White to Pale Yellow

    HScode:

    29142990

    Categories:

    Perfuming

    Characteristics
    PSA:

    17.07000

    XLogP3:

    3.84

    Appearance:

    Solid

    Density:

    0,997 g/cm3

    Melting Point:

    35-39 °C

    Boiling Point:

    125°C 0,5mm

    Flash Point:

    99°C

    Refractive Index:

    n20/D1.52

    Water Solubility:

    Slightly soluble in ethanol and chloroform. Partly soluble in water.

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    0.003 mm Hg at 25 °C (est)

    Vapor Density:

    >1 (Air = 1)

    Specific rotation:

    Optical rotation: +195.5 deg (c = 1.5 in CHCL3)

    Odor:

    at 100.00 %. grapefruit peel citrus gardenia woody

    Taste:

    Grapefruit taste

    Henrys Law Constant:

    Henry's Law constant = 1.4X10-4 atm-cu m/mole at 25 °C (est)

    Experimental Properties:

    Hydroxyl radical reaction rate constant = 1.5X10-10 cu cm/molec-sec at 25 °C (est)|Ozone reaction rate constant = 2.3X10-17 cu cm/molec-sec at 25 °C (est)

    Critical Temperature & Pressure:

    2-8°C

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

    Location:

    Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    51-100

    Year of Establishment:

    2019

  • Country Product Purchase Quantity Date Posted
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