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TYRA-300 powder

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CAS No.:

2800223-30-5

Port:

qingdao

Packaging:

bottle

Price valid (until):

2026-07-29

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Shandong zhishang chemical Co.,Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

D/P,L/C,D/A

Average Lead Time:

15 days

Qualification:

Main Products:

Dichloromethane,Linocaine hydrochloride

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Inquiry History

Description

Product Detail

CAS: 2800223-30-5
• English Name: TYRA-300 / Dabogratinib
• Molecular Formula: C₂₅H₂₄Cl₂N₆O₃S, Molecular Weight 559.47
• Purity: Reagent Grade 98%–99.66%
• Appearance: White / Off-White Powder
• Target: FGFR3 (Highly Selective, Weak Inhibition of FGFR1/2/4)
• Application: For Clinical Research on Urothelial Carcinoma and Achondroplasia (Phase II)

Items Specifications

ECHEMI Editorial Reference

Dabogratinib(TYRA-300) , a 3-pyridylindazole analog, is a reversible and selective inhibitor of FGFR3 with an IC50 of 11 nM in Ba/F3 cells. It also exhibit potent activity in human bladder cancer cell lines harboring FGFR3 activating fusions or mutations.

Basic Info

Product Name:
TYRA-300

Other Name:
TYRA-300;2,6-Diazaspiro[3.3]heptane, 2-[5-[5-[(1R)-1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]-2-pyridinyl]-6-(methylsulfonyl)-;(R)-5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-3-(6-(6-(methylsulfonyl)-2,6-diazaspiro[3.3]heptan-2-yl)pyridin-3-yl)-1H-indazole;TYRA-300(Dabogratinib);Tyra-300 99% Shaanxi Dideu Medichem

CAS No.:
2800223-30-5

Molecular Formula:
C25H24Cl2N6O3S

InChIKeys:
JOAFWIHZEBKYQK-OAHLLOKOSA-N

Molecular Weight:
559.47

EC Number:
610-261-8

Categories:
Bulk Drug Intermediates

Characteristics

Density:
1.58±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

Boiling Point:
791.2±70.0 °C(predicted)

PKA:
11.87±0.40(predicted)
Seller Information

Business Type:
Manufactory

Main Products:
Dichloromethane,Linocaine hydrochloride

Location:
BUILDING 1,HISENSE INTELLIGENCE VALLEY,NO.2116,OF PHOEIX ROAD, HIGH-TECH ZONE ,JINAN CITY ,SHANDONG PROVINCE,CHINA

Payment Terms:
D/P,L/C,D/A

Average lead Time:
15 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
11-50

Year of Establishment:
2016

Shandong zhishang chemical Co.,Ltd is a leading Manufactory supplier of Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1), Ethylene oxide-propylene oxide copolymer, Strontium carbonate based in Jinan, Shandong, China. With a commitment to quality and customer satisfaction, Shandong zhishang chemical Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1), Ethylene oxide-propylene oxide copolymer, Strontium carbonate, which are available at competitive prices. Shandong zhishang chemical Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

250 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	TYRA-300 Dabogratinib	1 G	Oct 27, 2026
United States	tyra-300	1 G	Oct 27, 2026
United States	tesa,reta,ghkcu,bac water	50 MT	Oct 26, 2026
China	TYRA-300	1 G	Oct 26, 2026
United States	dabogratinib (tyra-300)	1 G	Oct 25, 2026
United States	Dabogratinib	5 G	Oct 24, 2026
United States	Dabogratinib	1 G	Oct 24, 2026
Netherlands	Tyra-300/dabogratinib	1 G	Oct 23, 2026
Canada	Tyra300	6 G	Oct 23, 2026
Portugal	TYRA 300	100 G	Oct 22, 2026
United Kingdom	Tyra300	2 G	Oct 21, 2026
United States	Tyra-300	1 MT	Oct 20, 2026
South Africa	Tyra 300	19 G	Oct 20, 2026
Jordan	tyra-300	1 G	Oct 19, 2026
Germany	TYRA-300	5 MG	Oct 19, 2026
United States	Tyra-300	1 G	Oct 18, 2026
United Kingdom	Tyra 300	1 G	Oct 17, 2026
United Kingdom	Tyra 300	1 MT	Oct 16, 2026
Taiwan, China	Tyra 300	3 G	Oct 16, 2026
Singapore	Dabogratinib, Tyra 300	1 G	Oct 15, 2026

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TYRA-300 powder

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