—— Product Specifications ——

—— Product Detail ——

Product Overview

VB124, identified by the CAS number 2230186-18-0, is a high‑quality pharmaceutical intermediate produced by Chu Chang. It appears as a white powder and is guaranteed to meet a purity specification of at least 98 % as verified by high‑performance liquid chromatography (HPLC). The compound serves as a critical building block in the construction of more complex drug molecules, particularly those intended for therapeutic applications in the central nervous system, inflammation, or metabolic disorders. Its well‑defined chemical structure and consistent quality enable reproducible results in both research and pilot‑scale synthesis. VB124 is manufactured under strict Good Manufacturing Practice (GMP) conditions, with each batch subjected to comprehensive quality control testing including assay, moisture content, residual solvents, and related substances. The product is packaged in sealed, light‑protective containers to maintain stability during storage and transport. The reliability of supply and adherence to pharmacopoeial standards make VB124 a preferred choice for pharmaceutical companies seeking a dependable source of advanced intermediates.

Synthesis Process

The synthesis of VB124 is achieved through a multi‑step sequence beginning with a functionalized aromatic amine that undergoes a condensation reaction with a suitably protected carbonyl partner. This is followed by a cyclization step to form the core scaffold, after which a final deprotection and purification stage yields the target compound. Each reaction is monitored by TLC and HPLC to ensure completeness and to control impurity formation. The crude product is purified by column chromatography or recrystallization, then dried under vacuum to constant weight. The final material is packaged under an inert atmosphere to prevent moisture uptake and oxidative degradation.

Quality Specifications

VB124 is released according to a detailed specification sheet that includes assay (≥98.0 % by HPLC), moisture content (≤0.5 %), residue on ignition (≤0.1 %), heavy metals (≤10 ppm), residual solvents (ICH Class 3 limits), and a complete profile of related substances (≤0.5 % each). All test methods are validated and performed in an ISO/IEC 17025 accredited laboratory. Each batch receives a Certificate of Analysis (CoA) that documents the test results, batch number, manufacturing date, and expiration date.

Packaging & Storage

The product is supplied in sealed, tamper‑evident containers that provide protection from moisture, light, and oxygen. Standard packaging options include 1 kg aluminum foil bags, 5 kg paper drums, 25 kg cartons, and 50 kg iron drums. VB124 should be stored in a cool, dry place at 2–8 °C. Keep containers tightly closed when not in use. Under these conditions, the stability of VB124 is guaranteed for at least 24 months from the date of manufacture.

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

—— Q&A ——

Q1: How to confirm the product quality before placing orders?
A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

Q2: Can you supply free samples?
A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

Q3: How do you treat quality complaints?
A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

Q4: What is your MOQ? Is there a discount?
A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantities, we always support with better prices.

Q5: How to start orders or make payments?
A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.