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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Semaglutide for Sale > Semaglutide Best Weight Loss Peptides CAS: 910463-68-2 in stock
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Semaglutide Best Weight Loss Peptides CAS: 910463-68-2 in stock

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Unit Price:

$32/UNIT EXW

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CAS No.:

910463-68-2

Grade:

Pharmaceutical Grade

Content:

98%

Port:

Customer Location

Brand:

ZhanPian

Packaging:

5mg*10vials,10mg*10vials,15mg*10vials,20mg*10vials,

Price valid (until):

2027-09-16

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Retatrutide,Tirzepatide,Semaglutide,GHK-CU

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    Description



    Anna

    whatsapp:+86 17885951060


    Semaglutide is a GLP-1 receptor agonist with 94% sequence homology to native human GLP-1. It promotes weight loss through multiple mechanisms: red ucing appetite and food intake via central nervous system effects, slowing gastric emptying, and improving glycemic control through glucose-dependent insulin secretion. The extended half-life of approximately 7 days is due to albumin binding and resistance to DPP-4 degradation, enabling convenient once-weekly dosing. Clinical trials have demonstrated significant weight loss (mean 10–15% body weight reduction) in individuals with obesity when combined with lifestyle interventions. The weekly 2.4 mg maintenance dose is FDA-approved for chronic weight management and represents the standard clinical approach

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    Items Specifications
    Product Name emaglutide
    CAS No. 910463-68-2
    Storage Cool Dry Place
    Appearance White powder


      Product Functions  


    Blood sugar reduction and weight loss: As core efficacy, it significantly reduces glycated hemoglobin (average reduction of 1.52%) and weight (average weight loss of 12.4 kg).

    Cardiovascular protection: Reduces the risk of major adverse cardiovascular events by 16%. The US FDA has approved it for reducing this risk in adults with type 2 diabetes or who are obese/overweight and have cardiovascular disease.

    Kidney protection: Reduces the risk of composite renal endpoint events by 24%. The FDA has approved it for reducing the risk of renal function deterioration, renal failure, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease.

    Liver disease improvement: Demonstrates efficacy in treating metabolic dysfunction-associated steatohepatitis (MASH), with 62.9% of patients achieving MASH remission. The FDA has approved it for treating adult patients with MASH and moderate to advanced liver fibrosis.

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      Company Profile 


    Our company is a modern enterprise specializing in the research, development, production, and export of active pharmaceutical ingredients (APIs), pharmaceutical intermediates, and plant extracts. Our products are widely used in pharmaceutical preparations, health foods, cosmetics, dietary supplements, and food additives.

    Our factory covers 105 acres and is built to GMP standards. It boasts a rational layout and excellent environment, with large and medium-sized production workshops and refining workshops, equipped with an advanced quality inspection center and R&D laboratory. Our products have reached advanced domestic levels in terms of quality and technology.

    The company has long emphasized team building and technological improvement, employing modern production lines to ensure high-precision and high-efficiency production operations. From processing, extraction, and packaging to transportation, the entire process is completed in-house, ensuring quality and efficiency from the source. We are committed to the research and innovation of new raw materials and products, winning the trust and praise of customers both domestically and internationally.

    Through years of development, the company has accumulated rich experience in international trade, established a comprehensive marketing service system, and a stable customer network. Furthermore, the company has established long-term technical cooperation relationships with experts and professors from several universities and research institutes in the province, continuously enhancing its comprehensive R&D capabilities.

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      Product Detail  


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    ECHEMI Editorial Reference
    Semaglutide, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes.
    Semaglutide(910463-68-2) is an anti-diabetic medication that is sold under brand names such as Ozempic, Wegovy, and Rybelsus. It is used to treat type 2 diabetes and manage chronic weight. The drug functions similar to human glucagon-like peptide-1 (GLP-1) by increasing insulin secretion, which leads to improved sugar metabolism. It is distributed as a metered subcutaneous injection in a prefilled pen, or as an oral form. One of its advantages over other antidiabetic drugs is that it has a long duration of action, thus, only once-a-week injection is sufficient.
    The story of semaglutide began in the 1980s when scientists (such as Joel Habener and Jens Juul Holst) discovered GLP-1, a hormone in the human body that regulates blood sugar and appetite. However, its highly degradable nature limited its potential for medicinal use. In the 1990s, researchers at Novo Nordisk in Denmark, including Lotte Bjerre Knudsen, drew inspiration from the Gila monster's venom protein Exendin-4 and successfully developed the first GLP-1 drug, exenatide. In pursuit of a longer-acting drug, the Novo Nordisk team, led by Knudsen, created a once-daily liraglutide in the 2000s by structurally modifying human GLP-1 and adding fatty acid chains. Building on this success, the team further optimized the formula, ultimately leading to the development of semaglutide, with a longer half-life, by scientists including a research team led by Mads Krogsgaard Thomsen. It was approved in 2017 as a once-weekly blood sugar lowering drug (Ozempic), and in 2021 it shocked the world with its remarkable effects in the field of weight loss (Wegovy), evolving from a scientific concept into a benchmark drug that changes the treatment of metabolic diseases.
    ChEBI: Semaglutide is a polypeptide that contains a linear sequence of 31 amino acids joined together by peptide linkages. It is an agonist of glucagon-like peptide-1 receptors (GLP-1 AR) and used for the treatment of type 2 diabetes. It has a role as a hypoglycemic agent, a glucagon-like peptide-1 receptor agonist, an anti-obesity agent, a neuroprotective agent and an appetite depressant. It is a polypeptide and a lipopeptide.
    Semaglutide Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids, having a molecular mass of 4113 Dalton and a Molecular formula of C187H291N45O59.

    Certificates

    Basic Info
    Product Name:

    Semaglutide

    Other Name:

    Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide Injection

    CAS No.:

    910463-68-2

    Molecular Formula:

    C187H291N45O59

    InChIKeys:

    DLSWIYLPEUIQAV-CCUURXOWSA-N

    Molecular Weight:

    4113.57754

    Exact Mass:

    4113.122087 g/mol

    EC Number:

    203-405-2

    Color/Form:

    White to off-white

    Characteristics
    PSA:

    1650 Ų

    XLogP3:

    5.44520

    Critical Temperature & Pressure:

    Store at -20°C

    Research
    Class:

    GLP-1R agonist

    Status:

    FDA-approved (Ozempic / Wegovy / Rybelsus)

    Mechanism:

    Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

    Activity note:

    Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

    Source:

    Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

    Clinical Development:

    NCT03548935; NCT03552757; NCT01720446; NCT02692716

    FDA:

    Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

    References
    ChEMBL:

    CHEMBL2108724

    DrugBank:

    DB13928

    KEGG DRUG:

    D10025

    PubChem:

    PubChem

    Disclaimer:

    Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Retatrutide,Tirzepatide,Semaglutide,GHK-CU

    Location:

    Plot 1, No. 205 Tongbao Road, Jiangdong Subdistrict, Yiwu City, Jinhua City, Zhejiang Province

    Payment Terms:

    TT against B/L draft before shipment,100% TT in advance

    Year of Establishment:

    2026

  • Inquiry History
    491 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Weight Loss Semaglutide intermediate 99% White powder COA High Quality peptide GLP-1 910463-68-2

    5 MG Apr 11, 2024
    United States

    Gene-Biocon Semaglutide 910463-68-2 GLP-1analogs diabetes weight loss 96% White or off-white powder

    Dec 5, 2023
    United States

    Semaglutide 910463-68-2

    1 G Sep 21, 2023
    China

    Semaglutide CAS 910463-68-2

    1 KG Apr 16, 2026
    United States

    Sermaglutide 99% 910463-68-2

    2 KG Oct 21, 2023
    United Kingdom

    TGYFactory Supply Semaglutide Peptide 99% CAS 910463-68-2

    50 MT Nov 13, 2023
    Sri Lanka

    Bulk Supply 98% up Sermaglutide powder CAS 910463-68-2

    300 G Nov 18, 2023
    United States

    Semaglutide Ozempic Sermaglutide 99.9% white powder 910463-68-2 Teruiop

    500 G Oct 9, 2023
    United States

    Raw mateiral Semaglutide CAS 910463-68-2 99% White powder

    1000 G Sep 23, 2023
    Switzerland

    Semaglutide Ozempic Sermaglutide 99.9% white powder 910463-68-2 Teruiop

    5000 MT Sep 13, 2023
    United States

    High Purity Peptide Semaglutide 910463-68-2 With Safe Shipping

    1 G Sep 7, 2023
    United States

    10MG vial pack Semaglutide 99% 910463-68-2 GLP-1 Peptide

    10 MT Oct 18, 2023
    United States

    High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3

    60 MG Aug 4, 2025
    United States

    High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3

    10 MT Sep 19, 2025
    United States

    High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3

    Nov 13, 2024
    United States

    semaglutide CAS 910463-68-2 in stock 2-4 days safe delivery

    1 MT Nov 4, 2023
    United Kingdom

    API Pharmaceutical Chemical Grade Raw Materials CAS 910463-68-2 Semaglutide

    40 MT Sep 27, 2023
    United States

    High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3

    10  Sep 27, 2023
    China

    Semaglutide Tirzepatide for Weight Loss CAS: 910463-68-2 Retatrutide Cagrilintide

    1 MT Jul 5, 2025
    India

    Best Price 99% Semaglutide Peptide 10mg Vials Semaglutide CAS 910463-68-2

    100  Nov 8, 2023
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