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Semaglutide High Quality Sema Weight Loss Petpide 99.0% High Purity MOST-C RETA tirz

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CAS No.:

910463-68-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shen Zhen

Brand:

Packaging:

2mg 5mg 10mg 15mg 20mg 30mg per vial, 10 vials/boxes

Sample Available:

Yes

Price valid (until):

2026-08-31

Contact Supplier

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Yiwu Zhanpian Trading Co., Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against B/L draft before shipment,100% TT in advance

Qualification:

Main Products:

Retatrutide,Tirzepatide,Semaglutide,GHK-CU

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Product Details
Seller Information
Inquiry History

Description

Name:Nina

WhatsApp： +852 44859056

Email: 1635596903@qq.com

Model NO.	Semaglutide	Purity	>99%
Product Name	Peptide	Appearance	White Powder
Storage	Cool Dry Area	Sample	Available
MOQ	1box	Packaging	10mg/Vial, 10 Vials/ Box
Transport Package	Carton	Specification	2mg, 5mg, 10mg, 15mg, 20mg
Trademark	/	Origin	China

Semaglutide Detail

What is Semaglutide ?

Semaglutide acts similar to a human glucagon peptide-1 (GLP-1) that works similar to a hormone produced in our body called incretin. Incretin stimulates insulin secretion and sugar metabolism in response to increased glucose levels which usually occurs after meals. Patients with type 2 diabetes are usually at a total loss with incretin production.

Semaglutide is the newest GLP-1R agonist and was approved by the FDA for the treatment of T2DM in late 2017. The peptide is chemically similar to liraglutide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans. It is used to treat type 2 diabetes and manage chronic weight. The drug functions similar to human glucagon-like peptide-1 (GLP-1) by increasing secretion, which leads to improved sugar metabolism. It is distributed as a metered in a prefilled pen, or as an oral form. One of its advantages over other antidiabetic drugs is that it has a long duration of action.

Uses: Semaglutide is used along with an individualized low-calorie, low-fat diet and exercise program to help with weight loss in overweight adults who may also have high blood pressure, diabetes, or high cholesterol. Semaglutide is in a class of medications called incretin mimetics. It works by helping the pancreas to release the right amount of insulin when blood sugar levels are high. Insulin helps move sugar from the blood into other body tissues where it is used for energy. the stomach and may decrease appetite and cause weight loss.

Is semaglutide worth it for weight loss?

In these 68-week trials, semaglutide 2.4 mg was associated with significantly greater weight loss compared to placebo. Semaglutide differs from other GLP-1 receptor agonists by having a longer half-life and producing greater weight loss.

How much weight can you lose in a week with semaglutide?

Clinical trials have shown that study participants taking a weekly dose of semaglutide had an average reduction in body weight of 5-10 percent.

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ECHEMI Editorial Reference

Semaglutide (CAS: 910463‑68‑2) is a synthetic lipid‑modified peptide analogue, consisting of a 31‑amino‑acid backbone with a covalently attached C18 fatty di‑acid side‑chain via a hydrophilic spacer. It shares 94% amino‑acid sequence homology with native human GLP‑1 peptide. The substance appears as white to almost white hygroscopic powder, with molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and molecular weight of 4113.58 g/mol. Structural modifications grant it resistance against DPP‑4 enzymatic degradation and enable reversible binding to serum albumin, contributing to its extended in‑vivo half‑life property.

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Basic Info

Product Name:

Semaglutide

Other Name:

Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide

CAS No.:

910463-68-2

Molecular Formula:

C187H291N45O59

InChIKeys:

DLSWIYLPEUIQAV-CCUURXOWSA-N

Molecular Weight:

4113.57754

Exact Mass:

4113.122087 g/mol

EC Number:

203-405-2

Color/Form:

White to off-white

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

1650 Å²

XLogP3:

5.44520

Critical Temperature & Pressure:

Store at -20°C

Research

Class:

GLP-1R agonist

Status:

FDA-approved (Ozempic / Wegovy / Rybelsus)

Mechanism:

Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

Activity note:

Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

Source:

Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

Clinical Development:

NCT03548935; NCT03552757; NCT01720446; NCT02692716

FDA:

Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)

Disclaimer:

Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

See More Semaglutide Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H361 Suspected of damaging fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Semaglutide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Retatrutide,Tirzepatide,Semaglutide,GHK-CU

Location:
Plot 1, No. 205 Tongbao Road, Jiangdong Subdistrict, Yiwu City, Jinhua City, Zhejiang Province

Payment Terms:
TT against B/L draft before shipment,100% TT in advance

Year of Establishment:
2026

Inquiry History

425 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Weight Loss Semaglutide intermediate 99% White powder COA High Quality peptide GLP-1 910463-68-2	5 MG	Apr 11, 2024
United States	Gene-Biocon Semaglutide 910463-68-2 GLP-1analogs diabetes weight loss 96% White or off-white powder	2	Dec 5, 2023
China	Semaglutide CAS 910463-68-2	1 KG	Apr 16, 2026
United Kingdom	TGYFactory Supply Semaglutide Peptide 99% CAS 910463-68-2	50 MT	Nov 13, 2023
Sri Lanka	Bulk Supply 98% up Sermaglutide powder CAS 910463-68-2	300 G	Nov 18, 2023
China	Semaglutide Tirzepatide for Weight Loss CAS: 910463-68-2 Retatrutide Cagrilintide	1 MT	Jul 5, 2025
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	60 MG	Aug 4, 2025
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	10 MT	Sep 19, 2025
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	2	Nov 13, 2024
United States	semaglutide CAS 910463-68-2 in stock 2-4 days safe delivery	1 MT	Nov 4, 2023
India	Best Price 99% Semaglutide Peptide 10mg Vials Semaglutide CAS 910463-68-2	100	Nov 8, 2023
United Kingdom	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	10 MT	Nov 14, 2023
Singapore	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	2 G	Nov 3, 2023
United States	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	100 MT	Oct 26, 2023
United States	99.9% Purity Semaglutide Petide 910463-68-2 For Type II diabetes mellitus Obesity	50 MT	Nov 11, 2023
United States	GLP-1 Injection Weight Loss Tirzepatide Semaglutide 99% Purity Peptides CAS: 910463-68-2	1 MT	Oct 25, 2023
United States	Manufacturer Supply Weigh Loss Peptide Semaglutide 98% with Best Price CAS 910463-68-2	1	Dec 15, 2023
United Kingdom	Weight Loss GLP-1 Peptides Purity 99% Wholesales Price 2mg 5mg 10mg Semaglutide CAS: 910463-68-2	400	Nov 13, 2023
United Kingdom	l Weight Loss Semaglutide Tirzepatide Epitalon Retatrutide pharma Peptides Liraglutide CAS: 910463-68-2 Retatrutide CAS 2381089-83-2 Ly34379	20 MT	Nov 13, 2023
Canada	Semaglutide	1 G	Jun 24, 2024

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Semaglutide High Quality Sema Weight Loss Petpide 99.0% High Purity MOST-C RETA tirz

Product Details

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