Carmofur RC01613
61422-45-5
Pharmaceutical Grade
99%
Royalchem
25kg/drum
2029-12-31
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceCarmofur is a derivative of fluorouracil, an antimetabolite used as an antineoplastic agent. Target: Nucleoside antimetabolite/analogCarmofur, which is used in the clinic to treat colorectal cancers, is a potent AC inhibitor and that this property is essential to its anti-proliferative effects. Carmofur inhibited AC activity with a median effective concentration (IC50) of 29 ± 5 nM (mean ± standard error of the mean, s.e.m.; n = 4), whereas 5-FU had no such effect (IC50>1 mM). systemic a
Carmofur is an organohalogen compound and a member of pyrimidines.|Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.|Carmofur is an antimetabolite (pyrimidine analogue) antineoplastic derivative of 5-fluorouracil. (NCI)Basic Info-
Product Name:
Carmofur
Other Name:1(2H)-Pyrimidinecarboxamide,5-fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-;5-Fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinecarboxamide;1-(Hexylcarbamoyl)-5-fluorouracil;1-(n-Hexylcarbamoyl)-5-fluorouracil;HCFU;1-(Hexylcarbamyl)-5-fluorouracil;Carmofur;Mifurol;Yamaful
CAS No.:61422-45-5
Molecular Formula:C11H16FN3O3
InChIKeys:InChIKey=AOCCBINRVIKJHY-UHFFFAOYSA-N
Molecular Weight:257.26
Exact Mass:257.26
EC Number:1312995-182-4
UNII:HA82M3RAB2
NSC Number:758963
DSSTox ID:DTXSID2045941
NCI Thesaurus Code:C955
ATC Code:L - Antineoplastic and immunomodulating agents
HScode:2933599090
Categories:
Characteristics-
PSA:
78.5
XLogP3:2.6
Appearance:white to off-white
Density:1.3±0.1 g/cm3
Melting Point:110-111 °C
Refractive Index:1.525
Water Solubility:DMSO: >15mg/mL
Storage Conditions:2-8°C
Toxicity:Oral-rat LD50: 268 mg/kg; Oral-Mouse LD50: 1129 mg/kg
Flammability characteristics:Thermal decomposition releases toxic nitrogen oxides and fluoride fumes
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product