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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Semaglutide for Sale > 344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality
344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality buy - large image1
344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality buy - image1
344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality buy - image2
344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality buy - image3
344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality buy - image4
344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality buy - image5
344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality buy - image6

344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality

TDS 450 Inquiries

Unit Price:

$260/UNIT FOB

Get Latest Price
CAS No.:

910463-68-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

guangzhou

Brand:

HUANGXIN

Packaging:

10Vials/box

Sample Available:

Yes

Price valid (until):

2027-03-20

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
366 days
Qualification:
Main Products:

Polypeptide product

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    Contact Us

    Yiwu Huangxin Technology Co., Ltd.

    WS:+852 7027 1659

    Email:  huangxin6188@yeah.net

    • Sample Available

    • MOQ Flexible

    • Fast Quotation Within 24 Hours

    Please contact us for COA, HPLC reports, pricing, and bulk order information.


    Product Description

    FST344  is a high-affinity glycoprotein belonging to the follistatin family, consisting of a specific sequence of 344 amino acids. It is generated through the alternative splicing of the precursor mRNA encoded by the single FST gene .
    In laboratory settings, recombinant forms of this protein are utilized for experimental manipulation, typically presented as highly purified compounds for research purposes.

     



    Basic Information

       Items Specifications
    Product  Name FST344
    CAS number 2023788-19-2
    Purity 99%
    Appearance White or almost white powder
    Storage Dry and Cool Place

    Grade Standard

    Top Quality

    Grade Pharmaceutical Grade
    Specification 5mg 10mg 20mg



     

    Mechanism of Action

    Functioning as a potent protein-binding antagonist, FST344 operates by sequestering specific ligands to modulate cellular signaling pathways. Its core mechanisms include:
    • Activin Antagonism: FST344 binds directly to activin with high affinity, acting as a specific antagonist that prevents activin from interacting with its native receptors . This action inhibits the biosynthesis and secretion of pituitary follicle-stimulating hormone (FSH) .
    • Myostatin Modulation: It binds to myostatin, a member of the TGF-β superfamily that naturally restricts muscle growth. By inhibiting myostatin activity, FST344 removes the "brakes" on muscle development, thereby promoting myofiber hypertrophy and increasing skeletal muscle mass .
    • Signal Pathway Regulation: Through the neutralization of these ligands, FST344 influences downstream signaling cascades, such as the Smad pathway, facilitating cell proliferation, differentiation, and tissue homeostasis .

    Research Advantages

    FST344 is a pivotal subject in the fields of physiology, genetics, and regenerative medicine due to its specific regulatory roles:
    • Skeletal Muscle Enhancement: Studies in transgenic models demonstrate that the overexpression of FST344 leads to a significant increase in lean muscle mass and a reduction in body fat percentage without inducing cardiac hypertrophy or reproductive abnormalities .
    • Reproductive Endocrinology: It serves as a key tool for investigating the molecular mechanisms governing the hypothalamic-pituitary-gonadal axis and the regulation of fertility .
    • Metabolic and Disease Analysis: It offers insights into the complex roles of TGF-β superfamily inhibition in metabolic disorders, such as sarcopenia and non-alcoholic fatty liver disease, as well as its potential influence on tumor progression and immune responses .

    Applicable Contexts

    It is important to note that FST344 is strictly intended for controlled laboratory research purposes.
    It is utilized exclusively by scientists investigating the complexities of molecular biology, physiology, and genetics.

    Quality Control

    Each batch can be supplied with:

    ✔ Certificate of Analysis (COA)
    ✔ HPLC Chromatogram
    ✔ LC-MS Report
    ✔ Purity Testing Report
    ✔ Batch Number Traceability



    Packaging

    Standard Packaging:

    • 5mg / vial
    • 10mg / vial
    • 20mg / vial
    • 50mg / vial
    • 100mg / vial

    Bulk packaging available according to customer requirements.


    Shipping & Storage

    Storage:

    • Keep in dry and cool conditions
    • Store at low temperature
    • Protect from light and moisture

    Shipping:

    ✈ International Express
    ✈ Air Freight
    ✈ Customized logistics solutions available


    MOQ & Supply Ability

    MOQ: Negotiable
    Supply Capacity: Large-scale production available
    OEM Service: Available


    Why Choose Us

    ✔ Professional peptide manufacturer in China
    ✔ Strict quality management system
    ✔ Competitive factory pricing
    ✔ Fast response and global export experience
    ✔ Stable supply chain



    Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 1


    Shop 344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality-Detailed Image 2 Shop 344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality-Detailed Image 3

    Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 4 Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 5


    Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 6
    Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 7
    Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 8 Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 9
    Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 10
    Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 11

    Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 12 Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 13 Shop High Purity Peptide powder Retatrutide RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60 LY3437943 CAS 2381089-83-2-Detailed Image 14 Yiwu Huangxin Technology Co., Ltd. is located in Yiwu City, Zhejiang Province, China.

    We specialize in exporting high-quality scientific research chemicals, pharmaceutical intermediates, and peptide raw materials.

    The company boasts a professional technical team, advanced production equipment, and a rigorous quality management system. All products meet international safety and environmental standards.

    We offer dual customs clearance and door-to-door service, with business covering the United States, Canada, Australia, the United Kingdom, Germany, Spain, Italy, Sweden, the Netherlands, Poland, the Czech Republic, Mexico, Russia, Ukraine, and Kazakhstan, among other countries and regions.

    With years of export experience, we have established a stable reputation and reliable supply capabilities. Our extensive product line can meet your one-stop sourcing needs.

    We always adhere to the principles of "Quality First, Customer Supreme, Reputation Supreme" and sincerely welcome global customers to establish long-term, mutually beneficial cooperative relationships with us.

    ECHEMI Editorial Reference

    Semaglutide (CAS: 910463‑68‑2) is a synthetic lipid‑modified peptide analogue, consisting of a 31‑amino‑acid backbone with a covalently attached C18 fatty di‑acid side‑chain via a hydrophilic spacer. It shares 94% amino‑acid sequence homology with native human GLP‑1 peptide. The substance appears as white to almost white hygroscopic powder, with molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and molecular weight of 4113.58 g/mol. Structural modifications grant it resistance against DPP‑4 enzymatic degradation and enable reversible binding to serum albumin, contributing to its extended in‑vivo half‑life property.

    Certificates
    • 344 Fst344 | China Factory | Cosmetic Peptides | 99% Purity | Lyophilized Powder | hign quality Certificates 1 TDS

    Basic Info
    Product Name:

    Semaglutide

    Other Name:

    Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide

    CAS No.:

    910463-68-2

    Molecular Formula:

    C187H291N45O59

    InChIKeys:

    DLSWIYLPEUIQAV-CCUURXOWSA-N

    Molecular Weight:

    4113.57754

    Exact Mass:

    4113.122087 g/mol

    EC Number:

    203-405-2

    Color/Form:

    White to off-white

    Characteristics
    PSA:

    1650 Ų

    XLogP3:

    5.44520

    Critical Temperature & Pressure:

    Store at -20°C

    Research
    Class:

    GLP-1R agonist

    Status:

    FDA-approved (Ozempic / Wegovy / Rybelsus)

    Mechanism:

    Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

    Activity note:

    Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

    Source:

    Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

    Clinical Development:

    NCT03548935; NCT03552757; NCT01720446; NCT02692716

    FDA:

    Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

    References
    ChEMBL:

    CHEMBL2108724

    DrugBank:

    DB13928

    KEGG DRUG:

    D10025

    PubChem:

    PubChem

    Disclaimer:

    Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Polypeptide product

    Location:

    Unit 2, Building 141, Lane 23, Dongliantang Village, Yiwu City, Jinhua City, Zhejiang Province, Room 305

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    366 days

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    11-50

    Year of Establishment:

    2026

  • Inquiry History
    450 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Weight Loss Semaglutide intermediate 99% White powder COA High Quality peptide GLP-1 910463-68-2

    5 MG Apr 11, 2024
    United States

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    2  Dec 5, 2023
    China

    Semaglutide CAS 910463-68-2

    1 KG Apr 16, 2026
    United States

    Sermaglutide 99% 910463-68-2

    2 KG Oct 21, 2023
    United Kingdom

    TGYFactory Supply Semaglutide Peptide 99% CAS 910463-68-2

    50 MT Nov 13, 2023
    Sri Lanka

    Bulk Supply 98% up Sermaglutide powder CAS 910463-68-2

    300 G Nov 18, 2023
    United States

    10MG vial pack Semaglutide 99% 910463-68-2 GLP-1 Peptide

    10 MT Oct 18, 2023
    United States

    High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3

    60 MG Aug 4, 2025
    China

    Semaglutide Tirzepatide for Weight Loss CAS: 910463-68-2 Retatrutide Cagrilintide

    1 MT Jul 5, 2025
    United States

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    10 MT Sep 19, 2025
    United States

    High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3

    2  Nov 13, 2024
    United States

    semaglutide CAS 910463-68-2 in stock 2-4 days safe delivery

    1 MT Nov 4, 2023
    India

    Best Price 99% Semaglutide Peptide 10mg Vials Semaglutide CAS 910463-68-2

    100  Nov 8, 2023
    United States

    99.9% Purity Semaglutide Petide 910463-68-2 For Type II diabetes mellitus Obesity

    50 MT Nov 11, 2023
    United States

    GLP-1 Injection Weight Loss Tirzepatide Semaglutide 99% Purity Peptides CAS: 910463-68-2

    1 MT Oct 25, 2023
    United Kingdom

    Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2

    10  Oct 19, 2023
    United Kingdom

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    10 MT Nov 14, 2023
    Singapore

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    2 G Nov 3, 2023
    United States

    Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2

    100 MT Oct 26, 2023
    United States

    GLP-1 Injection Weight Loss Tirzepatide Semaglutide 99% Purity Peptides CAS: 910463-68-2

    1 MT Oct 20, 2023
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