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Direct supply from manufacturer, bulk high-purity Semaglutide with complete COA, vacuum filling into sterile glass vials available. buy - large image1

Direct supply from manufacturer, bulk high-purity Semaglutide with complete COA, vacuum filling into sterile glass vials available. buy - image1

Direct supply from manufacturer, bulk high-purity Semaglutide with complete COA, vacuum filling into sterile glass vials available. buy - image2

Direct supply from manufacturer, bulk high-purity Semaglutide with complete COA, vacuum filling into sterile glass vials available. buy - image3

Direct supply from manufacturer, bulk high-purity Semaglutide with complete COA, vacuum filling into sterile glass vials available. buy - image4

Direct supply from manufacturer, bulk high-purity Semaglutide with complete COA, vacuum filling into sterile glass vials available.

Name: Direct supply from manufacturer, bulk high-purity Semaglutide with complete COA, vacuum filling into sterile glass vials available.
Brand: Semaglutide
SKU: pr2607172265
Price: 5.76 USD
Availability: InStock

TDS 421 Inquiries

Unit Price:

$5.76/UNIT FOB

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CAS No.:

910463-68-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

ShangHai

Brand:

Semaglutide

Packaging:

10mg*10vials

Price valid (until):

2026-11-09

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Shandong Changxu Trade CO.,LTD

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

Peptide,reta

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Product Details
Seller Information
History Price
Inquiry History

Description

Self-Produced Semaglutide Long-Acting GLP-1 Peptide ≥99% HPLC Purity, Stable Mass Production Stock, Sincerely Recruit Global Laboratory Raw Material Distributors

Our factory owns a full closed-loop peptide production industrial park covering over 10,000 square meters with more than 10 years of independent R&D, synthesis and cross-border export experience. All production links including amino acid raw material procurement, solid-phase peptide synthesis, fatty acid side chain conjugation, multi-stage chromatographic purification, 0.22μm aseptic filtration, ultra-low temperature vacuum freeze-drying and sterile vial filling are finished in-house without outsourcing, realizing full-process independent quality control.

Semaglutide is a long-chain synthetic GLP-1 analog peptide widely adopted for academic laboratory research. It features Aib substitution at position 8 and C18 fatty diacid side chain linked via hydrophilic linker at Lys26, which greatly improves anti-DPP4 degradation capacity and prolongs molecular experimental half-life compared with ordinary short GLP peptides.

We adopt optimized Fmoc solid-phase peptide synthesis technology with accurately controlled coupling reaction parameters to raise full-length long peptide chain synthesis yield and cut incomplete fragment impurities from the source. Crude peptide undergoes four independent purification procedures: desalination, concentration, gradient elution and three-stage reverse-phase ultra-purification, to thoroughly remove reaction intermediates, heavy metals, residual organic solvents, single impurities and total impurities. The finished lyophilized powder has uniform texture, excellent water solubility and forms transparent solution without suspended particles. Its physical and chemical properties maintain stable during long-distance transoceanic shipping under fluctuating temperature and humidity, free from discoloration, caking or purity attenuation, fully matching the strict raw material standards of overseas universities, biological R&D institutions and third-party testing laboratories.

Items	Specifications
Name	Semaglutide
CAS No	910463-68-2
Molecular Weight	4113.58 Da
Appearance	White to off-white sterile loose lyophilized powder
Tested Purity	≥99% (Verified by RP-HPLC High Performance Liquid Chromatography)
Impurity Standard	Single impurity ＜0.1%, total impurities ＜0.5%, moisture ≤3%
Endotoxin Level	＜1 EU/μg, meets lab aseptic experiment requirements
Storage Condition	Sealed storage at -20℃, avoid light, moisture and repeated freeze-thaw cycles
Shelf Life	24 months under unopened standard refrigeration
Packaging Options	Blank wordless sterile glass vial vacuum filling

Six Core Competitive Advantages

1. Stable 99% Ultra-High Purity with Full Traceable Test Certificates Supporting Third-Party Re-Inspection

Ordinary GLP-1 long-chain peptides on the market only reach 95%-98% purity, while our Semaglutide adopts three-layer progressive ultra-purification process with stable HPLC tested purity ≥99%. Our impurity control standards far exceed common industrial specifications: single impurity <0.1%, total impurities <0.5%, moisture ≤3%, heavy metal and endotoxin indicators fully compliant with international lab reagent norms.

A complete set of test documents will be provided for every batch shipment, including official COA certificate, HPLC chromatogram spectrum, MS mass spectrum molecular weight identification report, moisture and ash test records. Each batch number, feeding log and inspection data are bound one by one for full traceability, supporting overseas clients to deliver samples to local third-party labs for secondary testing. We never exaggerate purity indicators or deliver goods with inconsistent batch quality.

2. Self-Optimized Long Peptide Synthesis & Conjugation Craft for Superior Molecular Stability

1.High-efficiency SPPS coupling technology: High-load resin carrier extends amino acid reaction time to maximize intact long peptide output and minimize defective peptide impurities;
Precise fatty acid conjugation process: Controlled pH and temperature reaction to ensure complete side chain linkage and reduce free fatty acid residual;
2.Three-stage layered chromatographic refinement: Primary purification removes macromolecular fragments, fine purification separates isomers, ultra-purification eliminates trace solvent residues for triple impurity interception;
3.-40℃ vacuum freeze-drying technology: Ultra-low temperature dehydration protects the complete spatial structure of Semaglutide molecules, greatly improving stability during long-term storage and international transportation;
5.Aseptic membrane filtration process: 0.22μm sterile filtration before filling removes microbial particles, satisfying basic aseptic requirements for endocrine cell culture and in-vitro biochemical experiments.

3. Self-Owned 100,000-Class Dust-Free Clean Workshop with Permanent Sufficient Stock

We are an authentic source manufacturer equipped with separated independent synthesis workshop, conjugation workshop, chromatography purification workshop, sterile freeze-drying workshop and constant temperature & humidity finished goods warehouse. Full sets of professional production & testing equipment are configured, including large-scale solid-phase synthesizers, industrial preparative liquid chromatographs, vacuum lyophilizer units, analytical balances, HPLC and mass spectrometry testing instruments.

An independent R&D laboratory and QC inspection center are built, staffed with full-time professional R&D engineers and quality inspectors to continuously optimize production craft and conduct random sampling inspection on finished products all year round.

Permanent large stock of Semaglutide is available, supporting small sample trial orders, medium bulk purchase orders and full-container mass export orders. Long-term cooperative partners will get priority production scheduling during sales peak seasons. Direct factory sales cut markup from multi-layer middlemen, offering highly competitive ex-factory prices for global buyers.

4. ISO9001 Standard Full-Process QC System with Complete Production Traceability

The whole factory operates closed-loop quality control procedures strictly following ISO9001 international quality management system, covering every single production link:

All incoming amino acid raw materials pass full purity and impurity inspection before entering production lines; unqualified raw materials will be rejected directly without feeding. Sampling inspection is carried out every 2 hours during synthesis, conjugation, purification and freeze-drying processes to monitor real-time reaction status. Multiple samples are extracted from each batch of finished goods for full re-inspection of purity, solubility and stability; defective products will be completely scrapped and never delivered out of factory.

Feeding records, equipment operation logs, test reports, filling records and delivery documents are archived permanently, available for customs inspection and client verification at any time. All workshops maintain constant temperature & humidity with regular sterilization to strictly control dust and microbial contamination, ensuring consistent uniform quality of every batch of peptide products.

5. Compliant Blank Neutral Export Packaging & Customization Service for Smooth Global Customs Clearance

Specially customized neutral packaging for cross-border trade avoids platform violation risks and brand infringement disputes:

Inner package: 2ml sterile transparent glass vials with fully blank surface without any words, logos or printed patterns, sealed by aluminum plastic composite caps for moisture-proof and light-shield preservation. Outer package: thick shockproof foam lining + multi-layer compression-resistant export cartons lined with moisture-proof aluminum foil bags to effectively prevent dampness, collision and breakage during sea transportation.

Diversified customization services are optional: adjustable filling dosage per vial, large bulk powder packages, customized neutral printing on outer cartons. We can adjust packaging specifications and matching customs clearance & test documents according to import regulations of different countries to simplify clients’ clearance procedures. The shelf life reaches 24 months under proper sealed -20℃ refrigerated storage.

6. One-Stop Professional Foreign Trade Service with Comprehensive Long-Term After-Sales Support

Our foreign trade team has rich practical experience in global peptide raw material export, fully familiar with laboratory reagent import policies and customs clearance rules of Europe, America, Southeast Asia, Middle East, Australia, Japan, South Korea and most regions worldwide:

1.Sample support: Small trial samples are available for clients to complete lab testing before placing formal bulk orders;
2.Fast delivery cycle: In-stock goods will be finished filling, inspection and packaging for shipment within 3-7 working days; customized specification orders will be delivered strictly on agreed schedules;
3.Multiple stable international special logistics channels with tightly sealed parcel protection and complete compensation mechanism for lost or damaged goods;
4.Exclusive one-on-one foreign trade specialist full follow-up service, timely message reply across time zones, covering inquiry reception, parameter confirmation, document issuing,
logistics tracking and basic peptide technical consultation;
5.Long-term after-sales guarantee: We will arrange reshipment or supplementary test documents immediately if clients receive damaged packages or missing batch certification files after cargo receipt. Continuous professional peptide technical consultation support is provided for long-term cooperative partners.

Shop semaglutide regulates blood sugar, reduces fat and enhances fat metabolism-Detailed Image 1

Shop semaglutide regulates blood sugar, reduces fat and enhances fat metabolism-Detailed Image 2

Shop semaglutide regulates blood sugar, reduces fat and enhances fat metabolism-Detailed Image 3

Shop semaglutide regulates blood sugar, reduces fat and enhances fat metabolism-Detailed Image 4

Shop semaglutide regulates blood sugar, reduces fat and enhances fat metabolism-Detailed Image 5

Shop semaglutide regulates blood sugar, reduces fat and enhances fat metabolism-Detailed Image 6

Shop semaglutide regulates blood sugar, reduces fat and enhances fat metabolism-Detailed Image 7

Shop semaglutide regulates blood sugar, reduces fat and enhances fat metabolism-Detailed Image 8

Shop Direct supply from manufacturer, bulk high-purity Semaglutide with complete COA, vacuum filling into sterile glass vials available.-Detailed Image 9

Global Long-Term Cooperation Invitation

Our full series of synthetic research peptides have been exported to more than 60 countries and regions around the world for years, stably serving thousands of overseas university laboratories, biological R&D institutions and scientific research raw material trading distributors. We accumulate massive repeat long-term cooperative clients relying on stable 99% ultra-high purity, sustainable sufficient production capacity and complete compliant foreign trade supporting system.

Now we sincerely recruit global long-term partners including regional exclusive agents, laboratory raw material distributors, cross-border traders and fixed procurement purchasers from academic labs. Exclusive preferential support policies for partners are listed below:

1.Direct factory ex-factory price with tiered volume discount, exclusive price protection for regional agents to avoid vicious price competition among peers;
2.Priority stock allocation, priority production scheduling for large orders during sales peak to guarantee stable local market supply for partners;
3.Full set of compliant marketing materials support: Wordless high-definition blank vial product photos, product parameter documents and COA test report templates, which can be directly used for online store listing and offline market promotion;
4.Flexible customization support: Negotiable neutral outer package and filling specification customization to assist partners in building their own independent distribution product line;
5.Dual professional technical & foreign trade support: Instant reply for basic peptide technical questions, timely update of national import customs policies to help partners complete smooth customs clearance.

We focus on sustainable win-win long-term cooperation rather than one-off short-term transactions. We look forward to expanding local laboratory raw material markets hand in hand with global trade partners. Feel free to contact us for free samples, detailed quotations and business negotiation at any time.

ECHEMI Editorial Reference

Semaglutide (CAS: 910463‑68‑2) is a synthetic lipid‑modified peptide analogue, consisting of a 31‑amino‑acid backbone with a covalently attached C18 fatty di‑acid side‑chain via a hydrophilic spacer. It shares 94% amino‑acid sequence homology with native human GLP‑1 peptide. The substance appears as white to almost white hygroscopic powder, with molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and molecular weight of 4113.58 g/mol. Structural modifications grant it resistance against DPP‑4 enzymatic degradation and enable reversible binding to serum albumin, contributing to its extended in‑vivo half‑life property.

Certificates

Basic Info

Product Name:

Semaglutide

Other Name:

Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide

CAS No.:

910463-68-2

Molecular Formula:

C187H291N45O59

InChIKeys:

DLSWIYLPEUIQAV-CCUURXOWSA-N

Molecular Weight:

4113.57754

Exact Mass:

4113.122087 g/mol

EC Number:

203-405-2

Color/Form:

White to off-white

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

1650 Å²

XLogP3:

5.44520

Critical Temperature & Pressure:

Store at -20°C

Research

Class:

GLP-1R agonist

Status:

FDA-approved (Ozempic / Wegovy / Rybelsus)

Mechanism:

Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

Activity note:

Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

Source:

Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

Clinical Development:

NCT03548935; NCT03552757; NCT01720446; NCT02692716

FDA:

Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)

Disclaimer:

Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

See More Semaglutide Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H361 Suspected of damaging fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Semaglutide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Peptide,reta

Location:
jinan

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2025

Shandong Changxu Trade CO., LTD

our main products are weight loss peptide, anti-wrinkle peptide, tanning titanium, and other products, reliable quality, committed to strict quality control and thoughtful customer service, our experienced staff is always available to discuss your requirements to ensure customer satisfaction. In addition, we have obtained ISO9001 and CE certification.

Company Profile
Weekly Price

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Inquiry History

421 Inquiries

Country	Product	Purchase Quantity	Date Posted
Austria	CBL-514	500 MG	Oct 28, 2026
United Kingdom	Semaglutide	1 G	Oct 27, 2026
Belgium	Semaglutide	1 MT	Oct 19, 2026
Chile	Semaglutide	10 MG	Oct 16, 2026
Slovakia	semaglutide	10 MG	Oct 15, 2026
Germany	Semaglutide	1 G	Oct 14, 2026
South Africa	Semaglutide	10 MT	Oct 11, 2026
United States	Semaglutide	1000 MT	Oct 6, 2026
United States	Semaglutide	10 MT	Sep 30, 2026
United States	Semaglutide	1000 KG	Sep 30, 2026
United States	Semaglutide	30 MG	Sep 28, 2026
United States	Semaglutide	10 MT	Sep 25, 2026
Philippines	Semaglutide	10 MG	Sep 20, 2026
India	Semaglutide	10 MG	Sep 18, 2026
United Kingdom	Semaglutide - Reta - Tirz	100 MG	Sep 17, 2026
United Kingdom	Semaglutide	10 G	Sep 17, 2026
United Kingdom	Retatruide	1 MT	Sep 15, 2026
United Kingdom	IGF-1 LR3	10 MT	Aug 28, 2026
Paraguay	Semaglutide Freeze-dried Vial	1 KG	Aug 27, 2026
United States	Semaglutide	2 MT	Aug 25, 2026

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