High-quality Cagrilintide Long Half-Life Signaling Widely Used in Pancreatic Receptor Binding Academic Research
TDS 168 Inquiries
910463-68-2
Pharmaceutical Grade
99%
guangzhou
band
2mg 5mg 10mg 15mg 20mg 30mg/vial 10vials/box
2026-08-17
Tirzepatide,Retatrutide,Semaglutide,GHK-Cu
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial Reference
Semaglutide (CAS: 910463‑68‑2) is a synthetic lipid‑modified peptide analogue, consisting of a 31‑amino‑acid backbone with a covalently attached C18 fatty di‑acid side‑chain via a hydrophilic spacer. It shares 94% amino‑acid sequence homology with native human GLP‑1 peptide. The substance appears as white to almost white hygroscopic powder, with molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and molecular weight of 4113.58 g/mol. Structural modifications grant it resistance against DPP‑4 enzymatic degradation and enable reversible binding to serum albumin, contributing to its extended in‑vivo half‑life property.
CertificatesBasic Info-
Product Name:
Semaglutide
Other Name:Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide
CAS No.:910463-68-2
Molecular Formula:C187H291N45O59
InChIKeys:DLSWIYLPEUIQAV-CCUURXOWSA-N
Molecular Weight:4113.57754
Exact Mass:4113.122087 g/mol
EC Number:203-405-2
Color/Form:White to off-white
Categories:
Characteristics-
PSA:
1650 Ų
XLogP3:5.44520
Critical Temperature & Pressure:Store at -20°C
Research-
Class:
GLP-1R agonist
Status:FDA-approved (Ozempic / Wegovy / Rybelsus)
Mechanism:Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.
Activity note:Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).
Source:Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI
Clinical Development:FDA:Ozempic, Wegovy, Rybelsus (approved 2017-12-05)
References-
ChEMBL:DrugBank:KEGG DRUG:PubChem:Literature:
NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)
Disclaimer:Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Tirzepatide,Retatrutide,Semaglutide,GHK-Cu
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Location:
RM 701, UNIT 108, 7/F, TWR B NEW MANDARIN PLAZA 14 SCIENCE MUSEUM RD TSIM SHA TSUI HONG KONG
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Year of Establishment:
2026
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Inquiry History168 Inquiries
Country Product Purchase Quantity Date Posted
United States
Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2
100 MT Oct 26, 2023
Canada
Semaglutide
1 G Jun 24, 2024
New Zealand
Semaglutide
1 G Mar 18, 2026
Vietnam
semaglutide powder
10 G Sep 26, 2024
India
Semaglutide
1.00 KG Oct 8, 2024
India
Semaglutide
1 KG Sep 29, 2024
Italy
Semaglutide
1 PCS Aug 17, 2026
Belgium
Semaglutide
1 MT Apr 14, 2025
United Kingdom
Semiglutide
1 MT Jan 29, 2024
United States
Semaglutide / terzeptide
100 Jan 26, 2024
United States
Semaglutide
1 G Jan 26, 2024
United Kingdom
Semiglutide
1 G Jan 10, 2024
Trinidad and Tobago
Semaglutide
10 G Jan 4, 2024
United States
semaglutide
1 G Dec 12, 2023
United States
Semaglutide
1 KG Dec 11, 2023
Chile
Semaglutide
10 MG Oct 16, 2026
Philippines
Semaglutide
10 MG Sep 20, 2026
United States
Semaglutide
10 MG Aug 17, 2026
United Kingdom
Semaglutide
10 MG Aug 7, 2026
Australia
Semaglutide
15 MG Jul 21, 2026 Post an enquiry for this product
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