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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Sermorelin Acetate for Sale > Lab Grade Custom Synthesized Semax Polypeptide Compound 99% Purity Research Raw Material
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Lab Grade Custom Synthesized Semax Polypeptide Compound 99% Purity Research Raw Material

TDS 2 Inquiries

Unit Price:

$50/UNIT FOB

Get Latest Price
CAS No.:

114466-38-5

Grade:

Reagent Grade

Content:

99%

Port:

Shenzhen City

Brand:

lq

Packaging:

5mg10mg

Price valid (until):

2027-09-15

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Retatrutide,Tirzepatide,Semaglutide,GHK-CU

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Items Specifications
    Product Name Semax Synthetic Polypeptide
    CAS No 114466-38-5
    Appearance White Lyophilized Powder
    HPLC Purity 99%
    Product Type Biochemical Intermediate
    Specification 5mg/Vial 10mg/Vial

      Product Overview

    Semax is a custom artificially synthesized linear polypeptide compound without unified public CAS registration number. It is prepared by standard solid-phase peptide synthesis technology, then purified via multi-gradient reversed-phase high-performance liquid chromatography, and finally processed into finished lyophilized powder through vacuum freeze-drying technology. All synthesis, purification, filling and sealing operations are completed inside closed dust-free purification workshops. Each batch of finished products will undergo strict HPLC purity testing, impurity content inspection, microbial limit test and comprehensive appearance inspection before delivery to ensure stable batch-to-batch quality consistency.

    Our Semax lyophilized powder is exclusively supplied as biochemical intermediate raw material for in-vitro academic laboratory scientific research purposes only. This product is strictly prohibited from being applied to human body injection, oral intake, skin external application, cosmetic raw material addition, clinical medication, health care product preparation and all other human-related consumption scenarios. All product design, production and packaging schemes are customized to meet the experimental demands of university life science laboratories, biomedical research institutes and biochemical R&D enterprises all over the world.

    The finished product presents uniform white lyophilized powder, featuring fine texture, no agglomeration, no color difference and no visible foreign impurities. The HPLC purity is stably controlled at 99%. The content of truncated peptide fragments, residual synthetic amino acid raw materials and inorganic salt impurities is kept at an extremely low level, which will not bring extra interference variables during cell experiments, intracellular metabolic pathway exploration and molecular mechanism research, ensuring high accuracy and excellent repeatability of experimental data.

    Core Product Advantages

    1. Stable Physicochemical Properties Vacuum freeze-drying molding technology effectively slows down the hydrolysis fracture of polypeptide molecular chains. Under sealed low-temperature storage conditions, the shelf life can reach up to 24 months. Sealed aluminum cap packaging can resist moisture erosion, oxygen oxidation and ultraviolet damage during long-distance international cross-border transportation, and the intrinsic physicochemical properties of the product will not deteriorate under conventional transportation environments.
    2. Excellent Water Solubility Performance The lyophilized powder can be rapidly and completely dissolved in sterile purified water, PBS buffer solution and all conventional laboratory aqueous solvent systems. No insoluble precipitates or suspended residues exist after dissolution. Researchers can freely prepare experimental solutions with different concentration gradients according to various experimental schemes, which is convenient for cell incubation, liquid-phase chromatographic detection and multiple biochemical reaction tests.
    3. Ultra-Low Impurity Interference Multi-stage gradient chromatographic purification thoroughly removes incompletely synthesized peptide segments, residual raw materials and inorganic salt impurities. The total impurity content is controlled at a very low level, which will not affect the observation of cell physiological state, intracellular signal pathway research and protein binding experiment results, greatly reducing the probability of experimental errors.
    4. Customizable Packaging Specifications We support flexible customized filling specifications for academic research trials. Large-capacity bulk drum packaging can also be customized according to customers’ long-term large-batch experimental demands. Each vial is tightly sealed with butyl rubber stopper and aluminum crimp cap to guarantee outstanding air tightness.

    Standard Storage Regulations

    1. Short-Term Temporary Storage (Within 3 Months) Tighten the bottle cap to realize complete airtight sealing, store in a cool and dry place away from direct sunlight, and place in a refrigerator at 2°C ~ 8°C. Do not open the cap frequently to avoid moisture absorption and air contact leading to molecular chain degradation.
    2. Long-Term Preservation (More Than 3 Months) Carry out secondary sealing treatment on the bottle mouth, store the whole product at a constant low temperature of -20°C. Repeated freezing and thawing cycles are strictly forbidden, otherwise the spatial conformation of the polypeptide will be destroyed, resulting in decreased biological activity and poor applicability for subsequent experiments.
    3. Storage Requirements After Dissolving Into Aqueous Solution The prepared aqueous experimental solution must be fully consumed within 7 days under 2°C ~ 8°C refrigeration environment. The residual waste liquid shall be discarded in accordance with laboratory biochemical waste disposal specifications to prevent microbial reproduction and solution deterioration.

    Approved Application Range

    This polypeptide raw material is only applicable to basic life science research projects carried out in university laboratories, biomedical R&D institutions and biochemical research enterprises, including but not limited to:

    1. Polypeptide molecular spatial conformation analysis and structural simulation research;
    2. Cell physiological mechanism exploration and basic cell-related experimental research;
    3. Intracellular enzyme activity detection and metabolic pathway research;
    4. Intracellular signal transduction mechanism exploration experiments;
    5. Biochemical reagent formula development and comparative verification tests.

    Any commercial behaviors such as medical diagnosis, clinical treatment and human body care are not allowed.

    Global Logistics & After-Sales Service System

    We support small sample trial orders and large-volume bulk wholesale orders. After payment confirmation, our warehouse team will complete vacuum packaging and arrange delivery within 1 to 2 working days. We have long-term cooperative global cross-border express companies including EMS, UPS, DHL and FedEx, covering most countries and regions in Europe, Southeast Asia, North America, Oceania and other areas worldwide. The whole transportation cycle is about 12 to 15 working days, and the whole logistics process can be tracked in real time.

    Our professional foreign trade service team provides one-stop supporting services for all cooperative purchasers: pre-sales product parameter consultation, personalized quotation formulation, customs clearance document sorting, post-delivery storage technical guidance, product quality inspection feedback and after-sales problem handling. We adhere to stable product quality, reasonable price and sincere service philosophy, and welcome academic researchers and biochemical raw material distributors all over the world to establish long-term stable win-win cooperative partnership with us.

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    Certificates

    Basic Info
    Product Name:

    Sermorelin Acetate

    CAS No.:

    114466-38-5

    Molecular Formula:

    C149H246N44O42S

    InChIKeys:

    BVLCEKWPOSAKSZ-YQMCHIOTSA-N

    Molecular Weight:

    3417.9 g/mol

    Exact Mass:

    3416.843184 g/mol

    Characteristics
    PSA:

    1510 Ų

    XLogP3:

    5.07090

    Research
    Class:

    GHRH analog (1–29 amino-terminal fragment, 29-amino-acid peptide amide)

    Status:

    FDA-approved diagnostic agent (Geref, discontinued). NOT for therapeutic use.

    Mechanism:

    A synthetic 29-amino-acid peptide (H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂) identical to the amino-terminal segment of endogenous human GHRH. Sermorelin binds to the GHRH receptor (GHRHR) on anterior pituitary somatotrophs, stimulating pulsatile GH synthesis and secretion via the cAMP/PKA pathway. Unlike exogenous GH, sermorelin preserves the endogenous GH pulsatility and IGF-1 feedback loop.

    EC50 (Ghrhr Ec50):

    ~0.1–1 nM (cAMP accumulation in rat pituitary cells)

    Source:

    DrugBank: DB00010. Frohman LA, et al. Endocr Rev. 1986;7(3):223–253.DOI

    Clinical Development:

    NCT00001390; NCT00527397

    FDA:

    Geref (approved 1991-10-11)

    References
    ChEMBL:

    CHEMBL1201555

    DrugBank:

    DB00010

    KEGG DRUG:

    D08554

    PubChem:

    PubChem

    Disclaimer:

    Sermorelin was FDA-approved as a diagnostic agent (Geref) for growth hormone deficiency but has been discontinued (not for safety reasons). It is NOT approved for anti-aging, bodybuilding, or therapeutic GH replacement. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Retatrutide,Tirzepatide,Semaglutide,GHK-CU

    Location:

    Plot 1, No. 205 Tongbao Road, Jiangdong Subdistrict, Yiwu City, Jinhua City, Zhejiang Province

    Payment Terms:

    TT against B/L draft before shipment,100% TT in advance

    Year of Establishment:

    2026

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Sermorelin acetate HGRH

    1 KG Nov 25, 2025
    South Korea

    Sermorlin Acetate

    10  Jul 25, 2025
    Post an enquiry for this product
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