Carbidopa Monohydrate CAS.38821-49-7
38821-49-7
Pharmaceutical Grade
99%
Shenzhen
Flying
10g/1kg/ 10kg/ 25kg
2026-08-25
vitamin
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceWhite or yellowish-white powder.
Carbidopa is the hydrate of 3-(3,4-dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa. It has a role as an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor, an antiparkinson drug, a dopaminergic agent and an antidyskinesia agent. It is a member of hydrazines, a hydrate, a monocarboxylic acid and a member of catechols. It contains a carbidopa (anhydrous).|Carbidopa is an Aromatic Amino Acid Decarboxylation Inhibitor. The mechanism of action of carbidopa is as a DOPA Decarboxylase Inhibitor.|Levodopa (L-Dopa) is an amino acid precursor of dopamine and is the most effective and commonly used drug in the treatment of Parkinson disease. Levodopa is usually combined with carbidopa, which is an inhibitor of L-amino acid decarboxylase, the plasma enzyme that metabolizes levodopa peripherally. Treatment with the combination of levodopa and carbidopa has been associated with mild and transient increases in serum enzymes in a proportion of patients and with very rare instances of clinically apparent acute liver injury.|Carbidopa is a hydrazine derivative of dopa. Carbidopa is a peripheral dopa decarboxylase inhibitor that is used as an adjunct to levodopa administration to prevent peripheral biosynthesis of levodopa to dopamine, thereby reducing peripheral side effects. Carbidopa does not penetrate the blood brain barrier so that levodopa, after it reaches the brain, can be metabolized to dopamine by dopa decarboxylase where it exerts its effect on dopamine receptors.|An inhibitor of DOPA DECARBOXYLASE that prevents conversion of LEVODOPA to dopamine. It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. It has no anti-parkinson activity by itself.Basic Info-
Product Name:
Carbidopa monohydrate
Other Name:Benzenepropanoic acid,α-hydrazinyl-3,4-dihydroxy-α-methyl-,hydrate (1:1),(αS)-;Benzenepropanoic acid,α-hydrazino-3,4-dihydroxy-α-methyl-,monohydrate,(S)-;Benzenepropanoic acid,α-hydrazino-3,4-dihydroxy-α-methyl-,monohydrate,(αS)-;Carbidopa monohydrate
CAS No.:38821-49-7
Molecular Formula:C10H14N2O4.H2O
InChIKeys:InChIKey=QTAOMKOIBXZKND-PPHPATTJSA-N
Molecular Weight:244.24
Exact Mass:244.105927
UNII:MNX7R8C5VO
NCI Thesaurus Code:C47431
HScode:2928000090
Categories:
Characteristics-
PSA:
117 Ų
Density:1.42 g/cm3
Boiling Point:528.7°C at 760 mmHg
Flash Point:273.5ºC
Toxicity:Oral-rat LD50: 4810 mg/kg; Oral-Mouse LD50: 1750 mg/kg
Flammability characteristics:Thermal decomposition to emit toxic nitrogen oxide fumes
Hazard IdentificationClassification of the substance or mixture
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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