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Lab Analytical Application Retatrutide CAS 2381089-83-2 Powder Triple Receptor Peptide

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CAS No.:

2381089-83-2

Grade:

regent Grade

Content:

98%

Port:

shenzhen

Brand:

rxc

Packaging:

20mg,30mg,10vials in one box or as your requirement

Price valid (until):

2026-09-05

 This product has been removed from the shop temporarily..

Hebei Runxuchen trading Co., LTD

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

peptide

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Product Name	Grade / Content	Price	Supplier Name	Details
Retatrutide \| US Warehouse \| GLP-1 GIP GCG Peptides \| 99.48% Purity \| 5mg 10mg 20mg 30mg Vials \| Lyophilized Powder	Pharmaceutical Grade/	$90-110/UNIT EXW	Hong Kong JuXing Biotechnology Co limited	Inquiry

Product Details
Seller Information
History Price
Inquiry History

Description

Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

Retatrutide, LY3437943

CAS#: 2381089-83-2

Molecular Formula: C221H342N46O68

Molecular Weight: 4731.33

Sequence: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Appearance: White Powder

Purity (HPLC): ≥99.0%

Single Impurity (HPLC): ≤1.0%

Sodium Content (HPLC): 5.0%-12.0%

Moisture Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Storage: Store at 2-8 degrees Celsius in a dry and cool place.

Packaging: 1g-1kg, plastic bottle

Intended Use: For scientific research purposes

Items	Specifications
Product Name	Retatrutide
CAS	2381089-83-2
Specification	5mg 10mg 12mg 15mg 20mg 30mg 50mg 60mg
Appearance	Powder
Purity	>98%
Moisture Content	≤8.0%
Acetate ion content	≤12%
Origin	Chain
Storage	2ºC- 8ºC, Well-Closed Containers

Product Description

Retatrutide (LY3437943) is a high-purity, research-grade synthetic triple agonist peptide, designed exclusively for laboratory scientific research and industrial R&D applications. It acts as a balanced agonist at GLP-1R, GIPR, and GCGR receptors, widely used in peptide chemistry, in vitro testing, metabolic pathway research, and pharmaceutical development studies under controlled lab conditions.

Our Retatrutide is produced under strict quality control systems, with purity verified by HPLC ≥ 98% and confirmed by Mass Spectrometry (MS). It is supplied as white to off-white lyophilized powder for excellent stability, easy handling, and reliable experimental repeatability.

This product is FOR RESEARCH & INDUSTRIAL USE ONLY. NOT FOR HUMAN CONSUMPTION, THERAPEUTIC, DIAGNOSTIC, OR VETERINARY USE.

Key Features

High purity: ≥ 98% (HPLC tested)
Lyophilized powder form for long-term stability
Strict batch-to-batch consistency
Full COA (HPLC, MS) available upon request
Manufactured in controlled cleanroom environment
Suitable for in vitro research and peptide development

Technical Parameters

Appearance: White to off-white lyophilized powder
Purity: ≥ 98% (HPLC)
Form: Lyophilized powder
Solubility: Soluble in water, PBS, DMSO
Storage: -20°C (long-term); avoid repeated freeze-thaw
Shelf Life: 2 years under proper storage
Packing: 5mg, 10mg, 15mg, 50mg, 100mg, 1g, bulk

1. Expertise in Peptide Synthesis

Extensive Experience: 7 Years of expertise in synthetic peptide development.

Skilled Team: Experts in solid-phase and liquid-phase synthesis.

2. Advanced Manufacturing Capabilities

Cutting-Edge Facilities: High-precision equipment ensuring purity and bioactivity.

Scalable Production: From milligram-scale research peptides to multi-kilogram industrial batches.

3. Innovation & Customer Commitment

Reliable Supply Chain: Competitive pricing & timely global delivery.

Global Reach: Trusted by researchers, pharmaceutical firms & industrial clients worldwide.

Compliance Statement

This product is sold only for research and industrial purposes. It is not intended for clinical, medical, or therapeutic applications. Users must comply with local laws, safety regulations, and ethical research guidelines.

company introduction:

Hebei Runxuchen Trading Co.,Ltd. is a manufacture company located in Shijiazhuang, where is very convenient to both

Beijing and Tianjin.

In the development of domestic users at the same time focus on the establishment of Hebei Runxuchen Trading Co.,Ltd

development of foreign users, after several years of the business has with Africa, Europe, Japan, Indonesia established a

stable supply of long-term relationship on this basis, Hebei Runxuchen Trading Co.,Ltd will adopt a more entrepreneurial

spirit to develop more production, and the world user friends to establish a broad business relationship.

Wish our products of competitive price, in-time delivery and good service help you the best, is willing to cooperate with

friends from all walks of life to create a better future.

ECHEMI Editorial Reference

Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
Retatrutide (LY-3437943) was discovered by the American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors) for obesity. The 2024 Lasker~DeBakey Clinical Medical Research Award has been given to Joel Habener and Svetlana Mojsov for their discovery of a new hormone GLP-1(7-37) and to Lotte Knudsen for her role in developing sustained acting versions of this hormone as a treatment for obesity.

Basic Info

Product Name:

Retatrutide

Other Name:

Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

CAS No.:

2381089-83-2

InChIKeys:

MLOLQJNKXBNWFW-SAGGEDDASA-N

Molecular Weight:

EC Number:

200-001-8

Color/Form:

White lyophilized

Categories:

Characteristics

Water Solubility:

Soluble in water (5mg/ml).

Storage Conditions:

-20°C

Critical Temperature & Pressure:

-20°C

Research

Class:

Triple agonist — GCGR, GIPR, GLP-1R

Status:

Investigational (Phase 3)

Mechanism:

Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

EC50 (Human GCGR):

5.79 nM

EC50 (Mouse GIPR):

0.191 nM

EC50 (Mouse GLP1R):

0.794 nM

EC50 (Mouse GCGR):

2.32 nM

EC50 (Human GLP1R):

0.775 nM

EC50 (Human GIPR):

0.0643 nM

Source:

Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

Clinical Development:

NCT04881760; NCT05882045; NCT06354660

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Jastreboff et al. (2023) — Phase 2 Trial; FDA Drugs@FDA

Disclaimer:

Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

See More Retatrutide Properties 

Seller Information

Business Type:
Manufactory

Main Products:
peptide

Location:
south road and north road

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2022
Hebei runxuchen trading Co., Ltd. is a modern and advanced enterprise specializing in the production and export of peptide products, synthetic peptides, cosmetic raw materials, beauty and slimming products etc Products are widely used in health products, peptides and other fields. Our plant covers an area of 1000 m². The proposed workshop will be built according to GMP standards. We provide our customers with quality products and first-class service. Now, we can provide G-KG service to our customers.
High-Quality Peptides: Our company specializes in premium-grade peptides, ensuring the highest standards of purity and efficacy. Each product undergoes rigorous testing to guarantee superior quality and performance.
Cutting-Edge Technology: We leverage the latest advancements in peptide synthesis and production technology. Our state-of-the-art facilities and innovative processes enable us to deliver peptides with exceptional precision and consistency.
Custom Solutions: We offer tailored peptide solutions to meet the specific needs of our clients. Whether you require bespoke formulations or custom quantities, our experienced team is dedicated to providing personalized support and solutions.
Extensive Expertise: With years of experience in the peptide industry, our team of experts is well-versed in the complexities of peptide development and applications. We are committed to providing insightful guidance and technical support to help you achieve your goals.
Comprehensive Product Range: Our diverse portfolio of peptide products covers a wide range of applications, including research, pharmaceutical development, and cosmetic formulations. This allows us to cater to various industries and meet different customer needs.
Weekly Price

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Inquiry History

7470 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Retatrutide	100 PCS	Oct 27, 2026
New Zealand	Retatrutide	20 PCS	Oct 27, 2026
Netherlands	Retatrutide	100 20' Fcl	Oct 27, 2026
United States	Retatrutide	300 MG	Oct 27, 2026
Canada	Retatrutide	1 G	Oct 26, 2026
Switzerland	Retatrutide	1 KG	Oct 26, 2026
United States	Retatrutide	10 MG	Oct 26, 2026
Australia	Retatrutide	30 MG	Oct 26, 2026
United States	Retatrutide	30 MG	Oct 26, 2026
United States	Tesa	2 MG	Oct 25, 2026
Colombia	Retatrutide	15 MG	Oct 25, 2026
United States	Retatrutide	10 G	Oct 25, 2026
Canada	Retatrutide	1 KG	Oct 25, 2026
United Kingdom	Retatrutide	1 G	Oct 25, 2026
Netherlands	Retatrutide	10 MG	Oct 25, 2026
Australia	Retatrutide	10 MG	Oct 25, 2026
Netherlands	Retatrutide	20 MG	Oct 25, 2026
Germany	Retatrutide	1 KG	Oct 25, 2026
United Kingdom	Retatrutide	10 G	Oct 25, 2026
United States	Retatrutide	20 MG	Oct 25, 2026

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Lab Analytical Application Retatrutide CAS 2381089-83-2 Powder Triple Receptor Peptide

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Inquiry History

Product Description

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Technical Parameters

Compliance Statement

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