GUANIDINEACETIC ACID | CAS 352-97-6

Product Overview

Guanidineacetic Acid (CAS: 352-97-6) is an organic compound and a naturally occurring metabolite of glycine in the human body. It serves as the direct biological precursor to creatine, playing a critical role in cellular energy metabolism. It is a white to off-white crystalline powder that is highly soluble in water.

Guanidineacetic Acid is also widely known as Glycocyamine, Guanidinoacetic Acid (GAA), N-Amidinoglycine, and Guanyl glycine.

Product Description

Guanidineacetic Acid is a white to off-white crystalline powder. It is the only known precursor of creatine, which is a key energy source for growth and metabolism. As a feed supplement, GAA functions as a direct metabolic precursor in creatine synthesis, helping to restore adequate cellular ATP levels and maintain overall energy balance. It can improve animal production and overall health by enhancing energy metabolism and protein synthesis.

The compound is stable under neutral and weakly alkaline conditions and can withstand high-temperature processing (stable below 120°C), making it suitable for feed pelleting and extrusion processes.

Technical Specifications

Applications

Animal Feed (Core Application)

Guanidineacetic Acid is a novel and highly effective nutritional feed additive. It is widely used in livestock, poultry, aquaculture, and pet feed to improve growth performance, feed conversion, and meat quality.

• Livestock (Pigs, Cattle, Sheep): Improves daily weight gain, reduces feed-to-meat ratio, and enhances lean meat percentage and body shape. In beef cattle, it reduces fat between muscle fibers and serum cholesterol while increasing beneficial fatty acids.

• Poultry (Broilers): Enhances growth performance, slaughter outcomes, meat quality, and antioxidant capacity.

• Aquaculture (Fish, Shrimp, Crabs): Improves swimming endurance, stress resistance, growth, survival rate, and meat yield.

• Pet Food: Enhances muscle strength, improves coat gloss, and alleviates post-exercise fatigue.

Food & Nutraceuticals

Used as a raw material for sports nutrition supplements and special dietary products. Compared to direct creatine supplementation, GAA offers lower gastrointestinal irritation and higher absorption efficiency.

Pharmaceutical & Research

• Pharmaceutical Intermediate: Used in the synthesis of guanidine-based drugs, such as guanethidine for cardiovascular treatment.

• Biochemical Reagent: Used in research on animal metabolism, creatine synthesis pathways, and as a nutrient supplement in cell culture.

Organic Synthesis

Serves as an intermediate in various organic synthesis processes.

Key Benefits

• Direct and efficient precursor to creatine, the primary energy source for muscles

• Improves growth rate and feed conversion efficiency in animals

• Enhances lean meat percentage and improves carcass quality

• Increases intramuscular fat content, improving meat tenderness and flavor while reducing drip loss

• Naturally occurring compound with no residue and no risk of drug resistance

• Stable under high-temperature feed processing (pelleting, extrusion)

• Cost-effective alternative to direct creatine supplementation with better bioavailability

• Multi-species application: swine, poultry, ruminants, aquaculture, and pets

Packaging Options

Storage Recommendations:

• Store in a cool, dry, well-ventilated area away from incompatible substances

• Keep container tightly closed

• Protect from moisture, direct sunlight, and high temperatures

• Avoid mixing transport with strong acids, strong bases, or oxidizing agents

• Shelf life: 24 months in sealed state