Retinol CAS NO.68-26-8 all-trans-Retinol (Vitamin A Alcohol) 99% HPLC Powder LYNA Bio

Product Introduction

Retinol (also known as all-trans-Retinol or Vitamin A Alcohol) is the primary animal form of vitamin A and a naturally occurring fat-soluble vitamin. It is a diterpenoid alcohol that plays an essential role in retinal metabolism, epithelial tissue growth and differentiation, bone development, reproduction, and immune function. Retinol is an effective antioxidant displaying lipoperoxy radical scavenging activity. This product is supplied as a high‑purity (≥99% by HPLC) yellow to orange powder and is widely used in pharmaceutical, cosmetic, and research applications.

Main Applications

✨ Cosmetics & Skincare

Retinol is widely regarded as one of the most effective over‑the‑counter anti‑aging ingredients available. It works by being converted to all‑trans retinoic acid within the skin—the biologically active retinoid that binds to nuclear receptors and modulates gene expression involved in cellular differentiation and proliferation. Key skincare benefits include:

• Anti‑aging and anti‑wrinkle – Stimulates collagen synthesis, inhibits collagenase, increases epidermal thickness, and improves skin barrier function. It reduces the appearance of fine lines, wrinkles, and rough skin surface caused by photodamage.

• Cellular renewal – Accelerates skin cell turnover, smoothing and minimizing the appearance of fine lines and wrinkles.

• Skin normalization – Normalizes cell keratinization and improves water uptake in the epidermis.

• Safety considerations – Generally recognized as safe (GRAS) by the FDA. However, retinol can cause mild skin irritation, which is concentration‑dependent. Common OTC formulations contain 0.04%–1% retinol. The EU SCCS has confirmed that retinol is safe for consumers at maximum concentrations of 0.05% in body lotions and 0.3% in rinse‑off and leave‑on products.

💊 Pharmaceuticals & Nutrition

As a vital form of vitamin A obtained through the diet, retinol is essential for human health, particularly in cellular protection, skin health, and the management of various medical conditions. It is used in nutritional supplements and pharmaceutical formulations for vitamin A deficiency and related conditions.

🧪 Research Applications

• Biochemical research – Retinol is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), which act as transcription factors to regulate the growth and differentiation of normal and malignant cells.

• Lipid peroxidation studies – Interactions between retinol and vitamin E (α‑tocopherol) in suppressing lipid peroxidation have been observed in biological membrane preparations.

• Analytical chemistry – Retinol exhibits fluorescence properties with maximum absorbance and emission at 325 nm and 520 nm (cyclohexane), respectively.

Stability & Handling

Retinol is highly susceptible to oxidative degradation and is intrinsically unstable when exposed to light, oxygen, heat, and acids. To maintain product integrity:

• Manufacturing – Should be processed at low temperatures, at pH between 6 and 8, under an inert atmosphere such as nitrogen or argon.

• Handling – Should always be handled under yellow light to prevent isomerization.

• Packaging – Must be packaged in opaque, airless, or air‑restrictive containers (e.g., dark glass, opaque plastic, or aluminum foil‑laminated packaging) to protect from light and air.

Packaging & Storage

• Packaging : Available in various sizes (e.g., 1 g, 5 g, 25 g) upon request

• Storage : Store in a freezer, tightly sealed, protected from light and moisture

• Shelf Life : Maintains stability for a limited period under recommended storage conditions

1. Ultra-High Purity

Each batch is synthesized and purified to >99% purity, ensuring reliable and reproducible results in sensitive experiments.

2.Accurate Dosing & Consistency
Our products are precisely weighed and vacuum-sealed under sterile conditions. Batch-to-batch consistency is rigorously maintained.

3.Endotoxin-Free & Sterile Processing
Manufactured in a cleanroom environment,  are free from endotoxins, microbial contamination, and other impurities that could interfere with cell-based or in vivo studies.

Who We Serve

-We proudly work with clients across North America, Europe, Asia, and Latin America, including:

-Biotech and pharma firms

-Research institutions & universities

-formulation startups

-CDMOs and CRO partners

We are a chemical manufacturer integrating production, processing and export, mainly dealing in pharmaceutical intermediates and various industrial chemicals. Since its establishment, the company adheres to the spirit of "integrity management, strict quality control, customer first", and has won praise from customers at home and abroad. We have also established an excellent professional sales team with rich international marketing experience, able to efficiently provide a range of products and professional services.

With synthetic biology platform technology as the core, it conducts innovative research and development, mainly engaged in the research and development of recombinantly expressed pharmaceutical  and proteins. Its products include innovative drugs, APIs, pharmaceutical and green synthetic industrial enzymes, functional  and protein products, etc.

At present, our company has realized the industrialization of a variety of biosynthetic   products and has obtained cooperation orders from many well-known domestic and foreign pharmaceutical companies.

1. How to make an order?

Send me message and let me know what you need with quantity , then i will calculate to you.

2. What's the lead time and shipping ways?

We will delivery to the package by USPS, FEDEX, DHL paket and UPS express to you after receive your payment, it would take around 5-15 days to your address.