Pharmaceutical Peptide LL-37 CAS:154947-66-7 for R&D

Name

Lithium Orotate

CAS number

5266-20-6

Synonym

Lithium orotate
5266-20-6
Orotic acid lithium salt monohydrate
lithium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate
lithium;2,4-dioxo-1H-pyrimidine-6-carboxylate
L2N7Z24B30
4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, monolithium salt
4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, lithium salt (1:1)

Related APIs #

Calcium Orotate (CAS: 22454-86-0)
Potassium Orotate (CAS:24598-73-0)
Magnesium Orotate (CAS:34717-03-8)
Zinc Orotate (CAS:68399-76-8)

Description

What is Lithium Orotate?
Lithium orotate is a compound that combines lithium, a naturally occurring mineral, with orotic acid. Unlike prescription lithium carbonate, which is often used for treating bipolar disorder, lithium orotate is available over the counter and is believed to have higher bioavailability, allowing for effective lower doses.

Applications of Lithium Orotate

1. Mood Regulation
Lithium orotate is primarily recognized for its mood-stabilizing properties. It may help regulate neurotransmitter activity in the brain, potentially alleviating symptoms of depression and anxiety. Users often report improved emotional stability and a sense of calmness after incorporating it into their routines12.

2. Cognitive Support
Emerging research indicates that lithium may enhance cognitive functions such as memory and focus. Some individuals use lithium orotate as a nootropic to support mental clarity. Studies suggest that it promotes neurogenesis, which is the growth of new neurons, thereby contributing to improved cognitive health.

3. Neuroprotective Effects
Lithium has been studied for its neuroprotective properties, which may help shield brain cells from damage associated with neurodegenerative diseases like Alzheimer's and Parkinson's. This protective effect could be beneficial in preserving cognitive function as one ages.

4. Stress Reduction
By modulating neurotransmitter levels, lithium orotate may assist in managing stress and promoting resilience against daily challenges. This can lead to an overall improvement in mental well-being.

5. Alcoholism Treatment
Research has indicated that lithium orotate may aid in alcohol rehabilitation. In clinical studies, patients treated with lithium orotate showed reduced relapse rates during recovery from alcoholism.

6. Potential Longevity Benefits
Some researchers speculate that lithium's ability to reduce inflammation and modulate cellular processes could contribute to longevity and overall health. However, more research is needed to substantiate these claims12.
Dosage and Safety Considerations
The typical dosage for lithium orotate ranges from 5 mg taken two to three times daily. This lower dosage is generally associated with fewer side effects compared to higher doses of prescription lithium medications24. However, individuals should consult healthcare professionals before starting supplementation, especially if they have existing health conditions or are taking other medications that affect the kidneys or serotonin levels35.

Conclusion
Lithium orotate presents a promising option for those seeking natural support for mood stabilization, cognitive enhancement, and stress management. While anecdotal evidence and preliminary studies suggest various benefits, further research is necessary to fully understand its efficacy and safety profile in different populations.

Molecular Formula

C₅H₃LiN₂O₄

Molecular Weight

162.1 g/mol

Appearance

White or almost white powder

Quality Standard

Enterprise standard; 98%- 102%(ICP-AES)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0-28 ℃ for short term (days to weeks) or 8-20 ℃ for long term (months to years).

Shelf Life

>2 years if stored properly

Sample package

Double plastic bags inside, fiber drum outside, any quantity available.

Commercial package

Aluminium Tin, Fiber drum

Origin

China