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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Semaglutide for Sale > Semaglutide 99% White Powder High Quality GLP-1 Receptor Agonist Raw Material
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Semaglutide 99% White Powder High Quality GLP-1 Receptor Agonist Raw Material

492 Inquiries

Unit Price:

$35-40/UNIT FOB

Get Latest Price
CAS No.:

910463-68-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SZ

Brand:

TY

Packaging:

5mg,10vials/box

Price valid (until):

2026-09-11

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

GLP-1,Retatrutide,Selank,Tirzepatide,MOTS-c

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Semaglutide is a long-acting GLP-1 receptor agonist widely applied in metabolic related research. It is supplied as fine white powder with verified purity up to 99%, strictly tested by HPLC to guarantee consistent quality between batches.

    This compound acts by binding to GLP-1 receptors and participates in the regulation of glucose metabolism and related signal pathways. It serves as a key research material for exploring metabolic mechanism, cardiovascular relevant studies and other preclinical laboratory projects.

    Our semaglutide raw powder adopts standardized production and purification procedures. Every batch comes with full test documents including HPLC, MS and COA for your verification. We maintain stable stock and flexible support for bulk inquiry, sample testing and custom packaging requirements.

    We can arrange fast global shipment with secure packing to protect product stability during transit. Our sales and technical team are ready to respond to your questions about specifications, testing data and delivery schedules. We look forward to establishing stable long-term cooperation for your laboratory research projects.

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    Product Overview


    Semaglutide is a advanced long-acting synthetic glucagon-like peptide-1 (GLP-1) receptor agonist, widely recognized as a core research compound in modern endocrinology, metabolic biochemistry, and physiological signal pathway exploration. Structurally optimized with fatty acid side-chain modification, this peptide molecule exhibits superior albumin-binding capacity, significantly extending its biological half-life and maintaining stable biological activity in long-term experimental environments.

    Our Semaglutide raw material is presented as fine uniform white crystalline powder, manufactured under standardized peptide synthesis, solid-phase purification, and high-precision chromatographic separation processes. The final purity is strictly tested and verified to reach 99%+ HPLC grade, ensuring ultra-low impurity content, excellent batch stability, and consistent experimental repeatability for academic and industrial laboratory research.

    Core Research Mechanism & Biological Properties

    As a potent and selective GLP-1 receptor agonist, Semaglutide mainly functions by targeting and activating GLP-1 receptors distributed in pancreatic tissues, intestinal tracts, and central nervous system. It participates in regulating multiple key physiological metabolic pathways.

    In glucose metabolism research models, Semaglutide can simulate natural GLP-1 biological activity, supporting the study of glucose-dependent insulin secretion modulation, helping researchers explore the mechanism of suppressing excessive glucagon output and improving glucose homeostasis balance.

    In gastrointestinal physiological research fields, this compound serves as an essential tool for studying gastric emptying rhythm, intestinal peristalsis regulation, and central satiety signal transmission pathways, providing reliable molecular support for digestive system physiological mechanism research.

    Benefiting from its unique long-acting molecular modification design, Semaglutide demonstrates far longer metabolic cycle compared with ordinary short-acting GLP-1 analogs. Its stable sustained biological activity allows continuous intervention in long-cycle animal experiments and chronic metabolic mechanism studies, greatly reducing experimental frequency and improving data stability.

    In addition, Semaglutide is also extensively applied in cardiovascular physiological research, lipid metabolism mechanism exploration, endocrine hormone balance research, and related preclinical pharmacological model construction, possessing extremely high academic research value and industrial research application prospects.



    Product Quality Advantages


    1. Ultra-High Purity: Up to 99% HPLC tested purity, strictly removed heteropeptides, residual solvents and heavy metal impurities, meeting top-grade laboratory research standards.

    2. Strict Quality Control: Each production batch undergoes full-process detection including HPLC purity analysis, MS molecular weight identification, moisture content test, residue detection and appearance inspection. Complete COA, HPLC and MS reports are provided for every batch.

    3. Excellent Batch Consistency: Fixed synthesis formula and standardized production process ensure zero obvious difference between different batches, guaranteeing stable and repeatable experimental data.

    4. High Solubility & Stability: Good water solubility, easy to prepare experimental solution; stable chemical properties, not easy to degrade under standard low-temperature storage conditions.


    Specification & Packaging Information 


    • Product Appearance: Fine white lyophilized powder / white crystalline powder

    • Purity: ≥99% (HPLC)

    • Available Package: Custom vial specifications and bulk powder packages are supported

    • Custom Service: Support customized dosage specification, private packaging, and personalized labeling according to customer laboratory research requirements


    Storage & Shelf Life


    To maintain the best biological activity and chemical stability, Semaglutide raw powder should be stored in a dry, dark and low-temperature environment. Recommended storage condition: -20℃ sealed refrigeration, avoiding high temperature, humidity and repeated freezing-thawing cycles. Under standard storage conditions, the maximum shelf life can reach 24 months.

    Company Service & Supply Capacity

    We are a professional supplier specializing in high-purity peptide raw materials and biochemical research compounds. We maintain sufficient spot inventory of Semaglutide all year round, supporting sample testing, small-batch trial orders and large-batch wholesale procurement.

    We provide one-stop service including product consultation, technical parameter provision, complete document support, customized packaging and fast global logistics. All goods are professionally vacuum-sealed and protected with freeze-dried special packaging to ensure zero deterioration during international transportation.

    Our professional technical team can provide professional parameter guidance, storage instructions and experimental preparation suggestions for laboratory researchers. We adhere to stable quality, competitive price and reliable after-sales service, committed to establishing long-term stable cooperative relations with global research institutions, laboratories and biochemical enterprises.

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    Salesperson:Genevieve

    whatsapp:+86155 3361 7103

    ECHEMI Editorial Reference
    Semaglutide, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes.
    Semaglutide(910463-68-2) is an anti-diabetic medication that is sold under brand names such as Ozempic, Wegovy, and Rybelsus. It is used to treat type 2 diabetes and manage chronic weight. The drug functions similar to human glucagon-like peptide-1 (GLP-1) by increasing insulin secretion, which leads to improved sugar metabolism. It is distributed as a metered subcutaneous injection in a prefilled pen, or as an oral form. One of its advantages over other antidiabetic drugs is that it has a long duration of action, thus, only once-a-week injection is sufficient.
    The story of semaglutide began in the 1980s when scientists (such as Joel Habener and Jens Juul Holst) discovered GLP-1, a hormone in the human body that regulates blood sugar and appetite. However, its highly degradable nature limited its potential for medicinal use. In the 1990s, researchers at Novo Nordisk in Denmark, including Lotte Bjerre Knudsen, drew inspiration from the Gila monster's venom protein Exendin-4 and successfully developed the first GLP-1 drug, exenatide. In pursuit of a longer-acting drug, the Novo Nordisk team, led by Knudsen, created a once-daily liraglutide in the 2000s by structurally modifying human GLP-1 and adding fatty acid chains. Building on this success, the team further optimized the formula, ultimately leading to the development of semaglutide, with a longer half-life, by scientists including a research team led by Mads Krogsgaard Thomsen. It was approved in 2017 as a once-weekly blood sugar lowering drug (Ozempic), and in 2021 it shocked the world with its remarkable effects in the field of weight loss (Wegovy), evolving from a scientific concept into a benchmark drug that changes the treatment of metabolic diseases.
    ChEBI: Semaglutide is a polypeptide that contains a linear sequence of 31 amino acids joined together by peptide linkages. It is an agonist of glucagon-like peptide-1 receptors (GLP-1 AR) and used for the treatment of type 2 diabetes. It has a role as a hypoglycemic agent, a glucagon-like peptide-1 receptor agonist, an anti-obesity agent, a neuroprotective agent and an appetite depressant. It is a polypeptide and a lipopeptide.
    Semaglutide Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids, having a molecular mass of 4113 Dalton and a Molecular formula of C187H291N45O59.

    Basic Info
    Product Name:

    Semaglutide

    Other Name:

    Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide Injection

    CAS No.:

    910463-68-2

    Molecular Formula:

    C187H291N45O59

    InChIKeys:

    DLSWIYLPEUIQAV-CCUURXOWSA-N

    Molecular Weight:

    4113.57754

    Exact Mass:

    4113.122087 g/mol

    EC Number:

    203-405-2

    Color/Form:

    White to off-white

    Characteristics
    PSA:

    1650 Ų

    XLogP3:

    5.44520

    Critical Temperature & Pressure:

    Store at -20°C

    Research
    Class:

    GLP-1R agonist

    Status:

    FDA-approved (Ozempic / Wegovy / Rybelsus)

    Mechanism:

    Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

    Activity note:

    Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

    Source:

    Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

    Clinical Development:

    NCT03548935; NCT03552757; NCT01720446; NCT02692716

    FDA:

    Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

    References
    ChEMBL:

    CHEMBL2108724

    DrugBank:

    DB13928

    KEGG DRUG:

    D10025

    PubChem:

    PubChem

    Disclaimer:

    Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    GLP-1,Retatrutide,Selank,Tirzepatide,MOTS-c

    Location:

    Room 704#-A010, Building 11, Block 16, Liangzhu Street, Yuhang District, Hangzhou City, Zhejiang Province

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    1

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2025

  • Inquiry History
    492 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Weight Loss Semaglutide intermediate 99% White powder COA High Quality peptide GLP-1 910463-68-2

    5 MG Apr 11, 2024
    United States

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    Dec 5, 2023
    United States

    Semaglutide 910463-68-2

    1 G Sep 21, 2023
    China

    Semaglutide CAS 910463-68-2

    1 KG Apr 16, 2026
    United States

    Sermaglutide 99% 910463-68-2

    2 KG Oct 21, 2023
    United Kingdom

    TGYFactory Supply Semaglutide Peptide 99% CAS 910463-68-2

    50 MT Nov 13, 2023
    Sri Lanka

    Bulk Supply 98% up Sermaglutide powder CAS 910463-68-2

    300 G Nov 18, 2023
    United States

    Semaglutide Ozempic Sermaglutide 99.9% white powder 910463-68-2 Teruiop

    500 G Oct 9, 2023
    United States

    Raw mateiral Semaglutide CAS 910463-68-2 99% White powder

    1000 G Sep 23, 2023
    United States

    10MG vial pack Semaglutide 99% 910463-68-2 GLP-1 Peptide

    10 MT Oct 18, 2023
    Switzerland

    Semaglutide Ozempic Sermaglutide 99.9% white powder 910463-68-2 Teruiop

    5000 MT Sep 13, 2023
    United States

    High Purity Peptide Semaglutide 910463-68-2 With Safe Shipping

    1 G Sep 7, 2023
    United States

    High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3

    60 MG Aug 4, 2025
    China

    Semaglutide Tirzepatide for Weight Loss CAS: 910463-68-2 Retatrutide Cagrilintide

    1 MT Jul 5, 2025
    United States

    High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3

    10 MT Sep 19, 2025
    United States

    High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3

    Nov 13, 2024
    United States

    semaglutide CAS 910463-68-2 in stock 2-4 days safe delivery

    1 MT Nov 4, 2023
    United Kingdom

    API Pharmaceutical Chemical Grade Raw Materials CAS 910463-68-2 Semaglutide

    40 MT Sep 27, 2023
    United States

    High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3

    10  Sep 27, 2023
    India

    Best Price 99% Semaglutide Peptide 10mg Vials Semaglutide CAS 910463-68-2

    100  Nov 8, 2023
    Post an enquiry for this product
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