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Dihexa Salable

175 Inquiries

Unit Price: Get Latest Price
CAS No.:

1401708-83-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

Flying

Packaging:

10g/1kg/ 10kg/ 25kg

Sample Available:

Yes

Price valid (until):

2026-09-11

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
Average Lead Time:
25 days
Qualification:
Main Products:

vitamin

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Superiority

    1.High quality and competitive price.
    2.Free sample for your evaluation.
    3.Promptly delivery by well-reputed shipping lines.
    4.Trial order is available for testing after samples.
    5.We will inform you all the information at every stage in advance.
    6.Packaging can gear to buyers’ special request. 

    Our service

    1. Reply your inquiry in 24 working hours.
    2. Customized design is available. OEM are welcomed.
    3. Exclusive and unique solution can be provided to our customer by our well-trained and professional engineers and
    staff.
    4. Professional factory: We are manufacturer, specializing in producing all kinds of herb extract for more than 10 years, competitive with good quantity.
    5. As an honest seller, we always use superior raw material, advanced machines, skilled technicians to ensure our products to be finished in high quality and stable feature.


    Hainan Flying International Trade Co., Ltd., was established in 2020, It is a professional supplier of Human APIs, Veterinary, Food Additives, Vitamins, Chemicals, Plant Extract and natural active ingredients. It has absolute advantage because of strong research strength, modern management system and high-quality marketing team.

    For customer’s needs, OEM service is also acceptable. If you have a good idea in new product production but lack of laboratory device and human resource, we are glad to solve this problem for you. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.

    .






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    RAQ





    Q1: How to confirm the Product Quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirement for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What's your MOQ ?
    A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
    Q: Is there a discount ?
    A: Yes, for larger quantity, we always support with better price.

    Q5: How to start orders or make payments ?
    A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.


    ECHEMI Editorial Reference

    Dihexa is a synthetic peptide-based compound and angiotensin IV analog. As a research and pharmaceutical raw material, Dihexa is characterized by its defined molecular structure and peptide properties. It is primarily used for research, analytical testing, compound evaluation, and pharmaceutical development.

    Basic Info
    Product Name:

    Dihexa

    Other Name:

    L-Isoleucinamide,N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-;N-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide;Dihexa;N-Hexanoic-Tyr-Ile-(6)aminohexanoic amide

    CAS No.:

    1401708-83-5

    Molecular Formula:

    C27H44N4O5

    InChIKeys:

    InChIKey=XEUVNVNAVKZSPT-JTJYXVOQSA-N

    Molecular Weight:

    504.7

    Exact Mass:

    504.66

    Characteristics
    Density:

    1.111±0.06 g/cm3(Predicted)

    Boiling Point:

    866.2±65.0 °C(Predicted)

    Research
    Class:

    Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator

    Status:

    Research compound — Not FDA approved

    Mechanism:

    A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.

    EC50 (HGF Binding KD):

    65 pM

    Activity note:

    Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).

    Source:

    Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.

    Clinical Development:

    NCT04488419

    References
    PubChem:

    PubChem

    UNII:

    9WYX65A5C2

    Disclaimer:

    Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    vitamin

    Location:

    Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment

    Average lead Time:

    25 days

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    Less than 5

    Year of Establishment:

    2023

  • Inquiry History
    175 Inquiries
    Country Product Purchase Quantity Date Posted
    Canada

    Dihexa lyophilized 1401708-83-5

    1  Aug 23, 2026
    Canada

    Dihexa 1401708-83-5

    1 G Mar 8, 2026
    Bulgaria

    Customized peptides high purity Dihexa with fast shipping door to door CAS 1401708-83-5

    10 G May 27, 2025
    United States

    Dihexa

    25 G Jan 26, 2025
    United States

    Dihexa

    500 G Aug 19, 2026
    Russia

    DIHEXA

    50.00 G Aug 14, 2024
    United States

    dihexa

    10 MG Sep 28, 2026
    Spain

    Dihexa

    100 MG Aug 30, 2026
    United Arab Emirates

    Diheza

    1 G Aug 28, 2026
    Canada

    Dihexa

    130  Aug 12, 2026
    Brazil

    dihexa

    90 MG Aug 4, 2026
    United States

    Dihexa raw powder

    10 G Jul 26, 2026
    Singapore

    Dihexa

    10 PCS Jul 15, 2026
    United States

    Dihexa

    1 G Jul 11, 2026
    Sweden

    Dihexa

    10 PCS Jul 8, 2026
    Australia

    Dihexa

    1 MT Jul 2, 2026
    United States

    Dihexa

    10 G Jun 14, 2026
    Germany

    Dihexa

    1 G May 25, 2026
    Thailand

    Dihexa

    1 G May 12, 2026
    United States

    Dihexa

    100 G May 4, 2026
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