Chonluten /99% purity/ 20mg CH20 / Chondroitin regulatory peptide

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• Amino Acid Sequence: Glu-Asp-Gly (Glutamic acid-Aspartic acid-Glycine), abbreviated as the single-letter sequence EDG.
• Structural Origin: Its sequence shares high homology with specific fragments of cartilage-specific proteins (such as type II collagen and proteoglycans), which endows it with a natural targeting affinity for chondrocytes.

• Substance Classification: It belongs to small-molecule linear tripeptide bioregulators.
• Physicochemical Parameters: Its molecular formula is C₁₁H₁₇N₃O₈, with a molecular weight of approximately 319.27 Da. The theoretical isoelectric point (pI) is approximately 3.2, making it acidic overall.
• Physicochemical Characteristics: It typically appears as a white or off-white powder. Due to its extremely small molecular weight and the presence of two acidic amino acid side chains, it exhibits excellent water solubility. It is highly soluble in water, normal saline, PBS buffer, and DMSO.

• Gene-level Regulation and Matrix Synthesis: Chonluten can penetrate the cell membrane and enter the nucleus, directly binding to specific DNA sequences on chromatin. It upregulates the gene expression responsible for synthesizing type II collagen (COL2A1) and aggrecan (ACAN) in chondrocytes, prompting the cells themselves to increase matrix production and thereby repair cartilage structure.
• Anti-degradation and Anti-inflammatory Effects: It can inhibit the expression of cartilage-degrading enzymes (such as matrix metalloproteinases, MMPs) and downregulate the signal transduction of pro-inflammatory cytokines (such as IL-1β and TNF-α). This alleviates joint inflammation and prevents further cartilage destruction.
• Anti-aging and Cellular Protection: Studies on cellular aging have found that Chonluten can reduce the levels of cellular senescence markers (such as p16, p21, and p53) while upregulating the expression of the SIRT6 protein, which is associated with longevity and genomic stability. This improves the proliferative capacity of fibroblasts and delays tissue degenerative changes.
• Activation of Cartilage Differentiation Factors: Research indicates that Chonluten may also upregulate SOX9 (the master transcription factor for chondrocyte differentiation and cartilage formation) and enhance the TGF-β and BMP signaling pathways, creating a favorable anabolic environment for cartilage repair.

1. How to make an order?
         Simply send us a message with the quantity you need. I will calculate the price and offer you a special discount. Once payment is confirmed, we will prioritize your order for immediate dispatch.

2. What's the lead time and shipping ways?
 * We will ship your order within 24–48 hours after payment is received.

  * We have dedicated shipping routes, allowing us to select the fastest and safest carrier for your specific destination—including FedEx, UPS, China Post, and other international express services. The estimated delivery time is approximately 7–15 business days.

  * We will also track the logistics throughout the entire process and update the logistics information for buyers in real time.

3. What's the payment methods?
         We could accept pay through Alipay, USDT, BTC and TT.

4.Does the product have a test report?
         Each batch of our products undergoes testing before leaving the factory, and a Certificate of Analysis (COA) report is issued.

5.Can customers customize their own labels?

        Custom labeling services are available. Please contact us to discuss your specific requirements prior to placing an order.

6.What is the product's shelf life?

       When unopened, our products have a shelf life of two years under both room temperature and frozen storage conditions. Therefore, you can rest assured that extended shipping times will not cause the product to expire or degrade.

7.How to store the peptides?

     The core principle for storing parenteral lyophilized powder is strict refrigeration and absolutely no freezing. Before reconstitution, it is generally stored in the dark at 2 to 8°C. Once mixed and dissolved with the solvent, it must be used within a very short period.
     Before Reconstitution (Original Packaging)
     Strict Refrigeration: The vast majority of parenteral lyophilized powders need to be stored in a refrigerator at 2 to 8°C.
      Absolutely No Freezing: Freezing will cause irreversible damage to the structure of proteins and peptides.
      Protection from Light and Moisture: The product must be kept in its original packaging to avoid direct sunlight and accidental exposure to moisture.
      After Reconstitution (Mixed State)
      Highly Time-Sensitive: Once the lyophilized powder is dissolved with a sterile solvent, the stability of the drug drops significantly. It usually needs to be administered immediately or within a very short window (e.g., a few hours).
      No Prolonged Storage: Under no circumstances should the reconstituted solution be stored in the refrigerator for use the next day. This can easily lead to loss of efficacy or severe bacterial contamination.

       Huatai Industrial Co., Ltd. is a professional enterprise engaged in the research, development, production, and sales of peptide products. We are committed to providing global customers with high-quality bioactive peptide raw materials and customized solutions. Our motto is: to manufacture products with care and serve customers with dedication.