Retatrutide 99% White powder High Quality retatrutide weight loss```

Year of Establishment: 2013 ｜ Business Type: Manufactory

Name:Jiang Kai

WeChat and WhatsApp： +852 4426 8722

Email:jesskk@synpeptide.com

Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

Retatrutide, LY3437943

CAS#: 2381089-83-2

Molecular Formula: C221H342N46O68

Molecular Weight: 4731.33

Sequence: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Appearance: White Powder

Purity (HPLC): ≥99.0%

Single Impurity (HPLC): ≤1.0%

Sodium Content (HPLC): 5.0%-12.0%

Moisture Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Storage: Store at 2-8 degrees Celsius in a dry and cool place.

Packaging: 1g-1kg, plastic bottle

Intended Use: For scientific research purposes

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Q1: May I get one sample before placing order?

Re: Yes, Sample are available. For normal products, samples are for free and you just need to bear the freight; For those high value products, you just need to freight and certain product cost. When we both cooperate for some times or when you are our VIP customer, free sample will be offered when you need.

Q2: Which payment is available for your company?

Re: T/T, PayPal,bank transfer etc. You can choose the one which is convenient for you.

Q3: How and when can I get my goods after payment?

Re: For small quantity products, they will be delivered to you by international courier(DHL, FedEx, TNT etc.) or by air. Usually it will cost 5-7days that you can get the goods after delivery.For large quantity products, shipping by see is worthwhile.It will cost 15 to 30 days to come to your destination port, which depends on where the port is.

Q4: Is there any possible to use my appointed label or package?

Re: Yes. If needed, we'd lik

Synpeptide Co., Ltd, established in 2013, is a pioneering force in the biotechnology sector. At the core of our operations is the unwavering commitment to our guiding principles: "Quality First, Service Supreme."

Company Overview:
Founded in 2013 and headquartered in Nanjing, our company has been a trailblazer in the field of biotechnology. We pride ourselves on our dedication to delivering cutting-edge products and unparalleled services.

Business Philosophy:
"Quality First, Service Supreme" encapsulates our business philosophy. We firmly believe that prioritizing quality in all aspects of our operations and providing exceptional service form the foundation for enduring success.

Key Products:
Our primary focus encompasses a range of products, including weight loss peptides, medicinal peptides, cosmetic peptides, and customized peptides. Notable among our weight loss peptide offerings are Semaglutide, Tirzepatide, Retatrutide, and others.

Mission:
Our mission is to spearhead advancements in biotechnology by consistently upholding the highest standards of quality and service. Through innovation and excellence, we aim to contribute to the betterment of global health and well-being.

Customized Peptides:
In addition to our standard product line, we specialize in crafting customized peptides tailored to meet the unique needs of our diverse clientele.

Future Vision:
As we move forward, Synpeptide Co., Ltd. is poised for continued growth and innovation. We are committed to expanding our product portfolio, staying at the forefront of technological advancements, and exceeding the expectations of our valued clients.

At Synpeptide Co., Ltd, we are not just shaping the future of biotechnology; we are pioneering a path towards a healthier and more sustainable world.

ECHEMI Editorial Reference
Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was al

so shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.