Cetirizine Excellent Quality
2 Inquiries
83881-51-0
Pharmaceutical Grade
99%
shenzhen
Fying
10g/1kg/ 10kg/ 25kg
2026-09-18
vitamin
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceCetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria. IC50 value:Target: Histamine H1 receptorCetirizine crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. It has also been shown to inhibit eosinophil chemotaxis and LTB4 release. At a dosage of 20 mg, Boone et al. found
Solid
Cetirizine is a member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively. It has a role as an anti-allergic agent, a H1-receptor antagonist, an environmental contaminant and a xenobiotic. It is a monocarboxylic acid, a member of piperazines, a member of monochlorobenzenes and an ether.|Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms,. One of the most common uses for this drug is for a condition called allergic rhinitis. The prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and up to 30%, according to self-reported nasal symptoms. Allergic rhinitis is associated with multiple missed or unproductive days at work and school, problems with sleep, and other difficulties with day to day activities for many individuals. Furthermore, some antihistamine agents that are used to treat this condition cause undesirable, sedating effects. Cetirizine is one of the first second-generation H1 antihistamines (SGAHs) formulated to selectively inhibit the H1 receptor without sedating effects.|Cetirizine and its enantiomer levocetirizine are second generation antihistamines that are used for the treatment of allergic rhinitis, angioedema and chronic urticaria. Cetirizine and levocetirizine have been linked to rare, isolated instances of clinically apparent acute liver injury.|A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.Basic Info-
Product Name:
Cetirizine
Other Name:Acetic acid,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-;Acetic acid,[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-;2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid;Cetirizine;(±)-Cetirizine;Cetirizin-Teva;Piriteze;Rigix;Allamine;Cetrin;Zetrinal;(2-[4-[(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-yl]-ethoxy)-acetic acid;130018-86-9
CAS No.:83881-51-0
Molecular Formula:C21H25ClN2O3
InChIKeys:InChIKey=ZKLPARSLTMPFCP-UHFFFAOYSA-N
Molecular Weight:388.89
Exact Mass:388.89
DSSTox ID:DTXSID4022787
Color/Form:Crystals from ethanol
ATC Code:R06AE07|R - Respiratory system
HScode:2933599090
Categories:
Characteristics-
PSA:
53
XLogP3:1.70
Appearance:Solid
Density:1.2±0.1 g/cm3
Melting Point:112.5 °C
Boiling Point:542.1±45.0 °C at 760 mmHg
Flash Point:281.6±28.7 °C
Refractive Index:1.589
Water Solubility:In water, 6.96X10+4 mg/L at 25 deg C (est)
Storage Conditions:Store at 20-25 deg C (68-77 deg F); excursions permitted to 15-30 deg C (59-86 deg F)
Vapor Pressure:2.98X10-11 mm Hg at 25 deg C (est)
PKA:1.52, 2.92 and 8.27
Henrys Law Constant:Henry's Law constant = 4.19X10-17 cu cm/molec-sec at 25 °C (est)
Dissociation Constants:1.52, 2.92 and 8.27|pKa1 = 2.70 (amine); pKa2 = 3.57 (carboxylic acid); pKa3 = 7.56 (amine) (est)
Collision Cross Section:200.8 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]
Experimental Properties:Crystals from isopropanol; mw 461.81; mp 225 °C. Soluble in water /Cetirizine dihydrochloride/|Hydroxyl radical reaction rate constant = 2.41X10-10 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
Switzerland
cetirizine
1 KG Feb 2, 2026 
United States
Cetirizine HCl
25 KG Apr 8, 2025 Post an enquiry for this product
