Dictamnine 98% Purity Research Grade Furoquinoline Alkaloid CAS 484-29-7 for Natural Product Reference Standard

Product Overview

Dictamnine is a naturally occurring furoquinoline alkaloid found in plants of the Rutaceae family, particularly in Dictamnus dasycarpus (white dittany) and various species of the genus Zanthoxylum. This compound is one of the major bioactive components of Bai Xian Pi (Dictamni Cortex), a traditional Chinese medicine, and is known for its antimicrobial, anti-inflammatory, and anticancer properties.

Chemically, dictamnine is 4,8-dimethoxyfuro[2,3-b]quinoline with the molecular formula C₁₂H₁₁NO₃ and a molecular weight of 217.22 g/mol. It appears as a white to off-white crystalline powder, soluble in methanol, ethanol, chloroform, and dimethyl sulfoxide. The compound is supplied at ≥98% purity as determined by HPLC analysis.

Synthetic Process:

This compound is obtained through isolation from natural plant sources:

Extraction: Dried Dictamnus root bark (Bai Xian Pi) or other Rutaceae plant material is extracted with methanol or ethanol. The extract is concentrated and subjected to liquid-liquid partitioning.

Purification: The alkaloid-enriched fraction is purified by silica gel column chromatography using a chloroform-methanol gradient system, followed by recrystallization to obtain pure dictamnine.

This product is a high-purity analytical reference standard intended for natural product and pharmacological research.

Research Applications

• Natural Product Chemistry: Used as a reference compound for furoquinoline alkaloid analysis

• Pharmacological Research: Evaluated for antimicrobial, anti-inflammatory, and anticancer activities

• Quality Control: Serves as a marker compound for Dictamnus cortex (Bai Xian Pi) standardization

• Medicinal Chemistry: Studied as a lead compound for drug development

Quality Specifications

• Purity: ≥98.0% determined by HPLC

• Identity confirmed by NMR and MS

• Each batch accompanied by Certificate of Analysis

• Stable for 36 months when stored at 2-8°C in sealed, light-protected containers

Packaging & Shipping

• Standard packaging: 20mg amber glass vials

• Custom packaging available upon request

• Shipped at ambient temperature

• International shipping available

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

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We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

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