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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > AOD 9604 for Sale > 5-AD Peptide Research Grade 1. High-pu PeptideLyophilized Powder Synthetic Polypeptide Laboratory Raw Material High Purity Peptide 5-AD Peptide for An
5-AD Peptide Research Grade 1. High-pu PeptideLyophilized Powder Synthetic Polypeptide Laboratory Raw Material High Purity Peptide 5-AD Peptide for An buy - large image1
5-AD Peptide Research Grade 1. High-pu PeptideLyophilized Powder Synthetic Polypeptide Laboratory Raw Material High Purity Peptide 5-AD Peptide for An buy - image1
5-AD Peptide Research Grade 1. High-pu PeptideLyophilized Powder Synthetic Polypeptide Laboratory Raw Material High Purity Peptide 5-AD Peptide for An buy - image2
5-AD Peptide Research Grade 1. High-pu PeptideLyophilized Powder Synthetic Polypeptide Laboratory Raw Material High Purity Peptide 5-AD Peptide for An buy - image3
5-AD Peptide Research Grade 1. High-pu PeptideLyophilized Powder Synthetic Polypeptide Laboratory Raw Material High Purity Peptide 5-AD Peptide for An buy - image4
5-AD Peptide Research Grade 1. High-pu PeptideLyophilized Powder Synthetic Polypeptide Laboratory Raw Material High Purity Peptide 5-AD Peptide for An buy - image5
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5-AD Peptide Research Grade 1. High-pu PeptideLyophilized Powder Synthetic Polypeptide Laboratory Raw Material High Purity Peptide 5-AD Peptide for An

TDS

Unit Price:

$103/UNIT FOB

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CAS No.:

386264-39-7

Grade:

Research Grade

Content:

99%

Port:

Hongkong

Brand:

Novio

Packaging:

5mg*10vials 10mg*10vials

Price valid (until):

2026-09-26

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Peptides,Cosmetic Raw Materials,Pharmaceutical Intermediates

  • Product Description

  • Seller Information

  • Description


      Product Detail  


                   

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    From a basic physicochemical perspective, 5-AD is a synthetically modified peptide. Mainstream research products, as determined by HPLC, have a purity ≥98%, with extremely low impurity content, making them suitable for high-precision experiments and in vivo animal studies. This product is typically a lyophilized powder with excellent water solubility, soluble in sterile pure water, buffer solutions, and other research solvents, facilitating experimental preparation. Storage conditions are generally -20°C, sealed and protected from light. The powder exhibits excellent stability and can be stored for extended periods. For prepared aqueous solutions, it is recommended to aliquot and freeze at low temperatures to avoid activity loss due to repeated freeze-thaw cycles. It is ideal for long-term laboratory experiments and large-scale research projects. Its unique molecular structure is its core advantage. This peptide does not bind to traditional growth hormone receptors (GHRs) and does not activate the body's growth chain reaction, fundamentally avoiding common interference factors in traditional growth hormone-related experiments such as abnormal physical development, elevated IGF-1, and drug resistance, significantly improving the accuracy and reliability of metabolic experimental data.

    Lipid metabolism regulation is the core and most mature research direction for 5-AD, and also the core research value of this peptide. In the body's metabolic mechanisms, lipid metabolism is mainly divided into two major processes: lipolysis and lipogenesis. Most metabolic research materials can only regulate one of these processes, while 5-AD can achieve bidirectional targeted regulation. Numerous experiments and rodent model experiments have confirmed that it can activate fat, accelerate hydrolysis and decomposition in adipose tissue, promote the release and oxidation of free fatty acids for energy, and significantly improve the body's lipolysis efficiency. Simultaneously, this peptide can effectively inhibit fat activity, blocking the lipogenesis pathway at the molecular level and reducing the conversion of excess energy into adipose tissue, thus achieving a bidirectional metabolic regulatory effect of "promoting decomposition and inhibiting synthesis."

    In specialized studies of obesity models, 5-AD has demonstrated unique research advantages. Traditional metabolic intervention materials usually require calorie restriction to achieve experimental effects, but multiple animal experimental data show that 5-AD can effectively reduce the accumulation of white adipose tissue in experimental animals and regulate body fat distribution under experimental conditions without calorie restriction, without interfering with normal feeding and basal metabolism. Unlike glucocorticoids and traditional growth hormones, 5-AD intervention does not cause significant abnormal fluctuations in blood glucose and insulin levels in experimental models, thus avoiding experimental interference problems. This makes it possible to conduct univariate studies on lipid metabolism mechanisms to the greatest extent possible, making it an ideal tool peptide for studying obesity pathology, metabolic disorder intervention, and fat loss mechanisms.

    Secondly, it has significant research value in optimizing energy metabolism. Energy metabolism imbalance and fat accumulation are essentially caused by a homeostatic imbalance between energy intake and expenditure. This can be addressed by regulating relevant pathways, increasing basal energy metabolism levels, accelerating lipid oxidation efficiency, and improving basal metabolism.




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    ECHEMI Editorial Reference
    sh-Oligopeptide-74 is a protein fragment which contains 16 amino acids and is produced synthetically to be identical to a fragment of the human protein, Somatropin. The fragment consists of the proper sequence of the 20 standard amino acids.

    Certificates
    • 5-AD Peptide Research Grade 1. High-pu PeptideLyophilized Powder Synthetic Polypeptide Laboratory Raw Material High Purity Peptide 5-AD Peptide for An Certificates 1 TDS

    Basic Info
    Product Name:

    AOD 9604

    CAS No.:

    386264-39-7

    Molecular Formula:

    C78H125N23O23S2

    Molecular Weight:

    1817.0974

    Research
    Class:

    Synthetic hGH fragment 177–191 (lipolytic peptide, 15-amino-acid cyclic)

    Status:

    Research compound — Not FDA approved. Phase 2b obesity trials completed, not advanced.

    Mechanism:

    A synthetic 15-amino-acid peptide (Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe, cyclized via Cys-Cys disulfide bond) derived from the C-terminal region (amino acids 177–191) of human growth hormone. AOD-9604 mimics the fat-metabolizing domain of hGH without stimulating IGF-1 or cell proliferation. It stimulates lipolysis via β3-adrenergic receptors and inhibits lipogenesis, producing selective fat reduction.

    Activity note:

    AOD-9604 is a lipolytic peptide fragment, not a traditional receptor agonist. Functional lipolytic activity is observed at micromolar concentrations in adipocyte assays. Does not bind GHR.

    Source:

    Ng FM, et al. J Endocrinol. 2000;165(3):595–605. Heffernan MA, et al. Am J Physiol Endocrinol Metab. 2000;279(3):E501–E507.DOI

    Clinical Development:

    ACTRN12605000111673

    References
    PubChem:

    PubChem

    Disclaimer:

    AOD-9604 is NOT FDA-approved or EMA-approved. Phase 2b clinical trials for obesity were completed but the program was not advanced to Phase 3. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptides,Cosmetic Raw Materials,Pharmaceutical Intermediates

    Location:

    Room 1359, Room 103, Building Jia 19, Jixiang Garden, Tongzhou District, Beijing

    Year of Establishment:

    2026

  • Country Product Purchase Quantity Date Posted
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