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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Febuxostat for Sale > Febuxostat CAS 144060-53-7 Selective Xanthine Oxidase Inhibitor for Gout and Hyperuricemia hfd
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Febuxostat CAS 144060-53-7 Selective Xanthine Oxidase Inhibitor for Gout and Hyperuricemia hfd

TDS 28 Inquiries

Unit Price:

$100-130/G FOB

Get Latest Price
CAS No.:

144060-53-7

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

5g, 25g, 100g, 500g

Sample Available:

Yes

Price valid (until):

2026-09-26

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    —— Product Specification ——

    Parameter Specification Details
    Product Name Febuxostat TMX-67; TEI-6720; Adenuric; Uloric
    CAS Number 144060-53-7 144060-53-7 
    Molecular Formula C₁₆H₁₆N₂O₃S — 
    Molecular Weight 316.37 g/mol — 
    Appearance White to off-white solid powder Visual inspection 
    Purity ≥98.0% Determined by HPLC 
    Melting Point 209 – 212°C — 
    Solubility Soluble in hot methanol; practically insoluble in water  —
    Storage 2-8°C for short-term; -20°C for long-term Sealed containers, protect from moisture and light
    Packaging 10mg, 25mg, 50mg, 100mg, 500mg, 1g, 5g Amber glass vials
    Application Research use only Enzyme inhibition studies, gout and hyperuricemia research


    —— Product Detail ——

    Product Overview

    • Febuxostat (CAS 144060-53-7), also known as TMX-67 or TEI-6720 and marketed under the brand names Adenuric and Uloric, is a potent, selective, non-purine xanthine oxidase inhibitor . It appears as a white to off-white solid powder with the molecular formula C₁₆H₁₆N₂O₃S and a molecular weight of 316.37 g/mol . Its chemical name is 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid .


    Packaging & Shipping

                  • Research quantities: 5mg, 10mg, 25mg amber glass vials

                  • Bulk quantities: 50mg, 100mg amber glass bottles

                  • Custom packaging available upon request

                  • Not classified as hazardous material for transport under normal conditions

                  • Product for research and analytical use only; not for human therapeutic use

    Shop CAS 18048-64-1 Eltrombopag Intermediate for Pharmaceutical Research  kr-Detailed Image 1

    — Company profile ——


     Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 1

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

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    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    ECHEMI Editorial Reference
    Crystalline SolidFebuxostat, a selective xanthine oxidase inhibitor, was launched for the chronic management of hyperuricemia in patients with gout. Hyperuricemia is defined as a serum uric acid concentration exceeding the limit of solubility. It predisposes affected persons to gout, a disease characterized by the formation of crystals of monosodium urate or uric acid from supersaturated fluids in joints and other tissues. Crystal deposition is asymptomatic, but it is revealed by bouts of
    Febuxostat is a 1,3-thiazolemonocarboxylic acid that is 4-methyl-1,3-thiazole-5-carboxylic acid which is substituted by a 3-cyano-4-(2-methylpropoxy)phenyl group at position 2. It is an orally-active, potent, and selective xanthine oxidase inhibitor used for the treatment of chronic hyperuricaemia in patients with gout. It has a role as an EC 1.17.3.2 (xanthine oxidase) inhibitor. It is an aromatic ether, a nitrile and a 1,3-thiazolemonocarboxylic acid.|Febuxostat is a xanathine oxidase (XO) inhibitor indicated in patients with gout suffering from hyperuricemia and is used in its chronic management. Febuxostat is not recommended for the treatment of asymptomatic hyperuricemia. Febuxostat is marketed under the trade name Uloric by Takeda Pharmaceuticals America, Inc., and was approved by the FDA in February 2009.|Febuxostat is a Xanthine Oxidase Inhibitor. The mechanism of action of febuxostat is as a Xanthine Oxidase Inhibitor.|Febuxostat is a newly introduced nonpurine xanthine oxidase inhibitor used for the treatment of gout. Chronic febuxostat therapy has been associated with minor serum aminotransferase elevations, but has yet to be linked to cases of clinically apparent acute liver injury.|Febuxostat is an orally available, non-purine inhibitor of xanthine oxidase with uric acid lowering activity. Upon oral administration, febuxostat selectively and noncompetitively inhibits the activity of xanthine oxidase, an enzyme that converts oxypurines, including hypoxanthine and xanthine, into uric acid. By inhibiting xanthine oxidase, uric acid production is reduced and serum uric acid levels are lowered. Febuxostat may provide protection against acute renal failure caused by the excessive release of uric acid that occurs upon massive tumor cell lysis resulting from the treatment of some malignancies.|A thiazole derivative and inhibitor of XANTHINE OXIDASE that is used for the treatment of HYPERURICEMIA in patients with chronic GOUT.

    Certificates
    • Febuxostat CAS 144060-53-7 Selective Xanthine Oxidase Inhibitor for Gout and Hyperuricemia hfd Certificates 1 TDS

    Basic Info
    Product Name:

    Febuxostat

    Other Name:

    5-Thiazolecarboxylic acid,2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-;2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid;TEI 6720;TMX 67;2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid;Febuxostat;FBX;Uloric;Feburic;Febugood;Febutaz;Zurig;2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid;2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid;Adenuric

    CAS No.:

    144060-53-7

    Molecular Formula:

    C16H16N2O3S

    InChIKeys:

    InChIKey=BQSJTQLCZDPROO-UHFFFAOYSA-N

    Molecular Weight:

    316.37500

    Exact Mass:

    316.37

    UNII:

    101V0R1N2E

    NSC Number:

    758874

    DSSTox ID:

    DTXSID8048650

    NCI Thesaurus Code:

    C65629

    ATC Code:

    M04AA03|M - Musculo-skeletal system

    HScode:

    2934100090

    Characteristics
    PSA:

    111.45000

    XLogP3:

    3.9

    Appearance:

    Crystalline Solid

    Density:

    1.31 g/cm3

    Melting Point:

    238-239ºC

    Boiling Point:

    536.6ºC at 760 mmHg

    Flash Point:

    278.3ºC

    Refractive Index:

    1.605

    Vapor Pressure:

    2.41E-12mmHg at 25°C

    Collision Cross Section:

    180.6 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    28 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Febuxostat

    1.00 KG Jan 19, 2024
    India

    Febuxostat

    5.00 KG Jan 22, 2024
    Pakistan

    Febuxostat

    800.00 KG Aug 4, 2026
    India

    FEBUXOSTAT USP

    40.00 KG Oct 16, 2025
    India

    Febuxostat 

    100.00 KG Sep 20, 2026
    Philippines

    Febuxostat

    1 KG Jun 2, 2026
    India

    Febuxostat

    1.00 KG May 9, 2026
    India

    Febuxostat 

    1.00 KG Apr 21, 2026
    India

    Febuxostat

    2 MT May 17, 2024
    India

    Febuxostat 

    1.00 MT Jun 16, 2026
    India

    Febuxostat

    1.00 KG Jun 4, 2026
    India

    Febuxostat

    1.00 KG May 27, 2026
    India

    Febuxostat

    100.00 KG Apr 23, 2026
    Pakistan

    Febuxostat

    300.00 KG Feb 24, 2026
    Pakistan

    Febuxostat

    50 KG Jan 12, 2026
    India

    FEBUXOSTAT 

    25.00 KG Mar 25, 2025
    India

    Febuxostat

    1.00 KG Mar 15, 2024
    India

    Febuxostat

    200.00 KG Jun 22, 2026
    Pakistan

    Febuxostat

    300.00 KG Apr 20, 2026
    Pakistan

    Febuxostat

    300.00 KG Mar 16, 2026
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