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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Retatrutide for Sale > Retatrutide High purity Adamax Raw white Powder 5mg 10mg
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Retatrutide High purity Adamax Raw white Powder 5mg 10mg

TDS 6811 Inquiries

Unit Price:

$35-45/UNIT EXW

Get Latest Price
CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

DDP

Brand:

Pharma;Conutrix

Packaging:

10 vials/box

Price valid (until):

2026-09-27

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail 


    Retatrutide (LY3437943) Triple Receptor Agonist

    Basic Chemical Specifications

    • CAS No.: 2381089-83-2
    • Alias: LY3437943
    • Amino Acid Count: 39 modified amino acids with C20 fatty diacid linker
    • Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈
    • Molecular Weight: ~4256 Da
    • Appearance: Pure white lyophilized crystalline powder
    • Standard Vial Pack: 5mg / 10mg / 15mg / 20mg per sterile glass vial
    • HPLC Purity: ≥99% research grade
    • Disclaimer: Strictly for laboratory research use only, not approved for human injection, oral intake or clinical treatment

    Product Introduction & Core Mechanism

    Retatrutide (LY3437943) is the world’s first advanced triple agonist peptide developed for metabolic research, simultaneously activating three key metabolic receptors: GLP‑1R, GIPR and Glucagon Receptor (GCGR). The unique C20 fatty acid side chain binds albumin in plasma, extending half-life to around 6 days to support once-weekly administration in preclinical trials, far more potent than single GLP‑1 agonists or dual GIP/GLP‑1 peptides like Tirzepatide.

    Three synergistic metabolic pathways work together:
    1. GLP‑1 Receptor Activation

      Suppresses central appetite signals, slows gastric emptying, lowers postprandial blood glucose and inhibits excess glucagon secretion to reduce calorie intake efficiently.
    2. GIP Receptor Activation

      Boosts glucose-dependent insulin secretion from pancreatic beta cells, improves whole-body insulin sensitivity and optimizes adipose lipid metabolism.
    3. Glucagon Receptor Activation

      Elevates systemic energy expenditure, accelerates hepatic lipolysis and fat thermogenesis, targeting visceral fat loss and non-alcoholic fatty liver research, a core advantage absent in single/dual agonists.

      Combined lab trial data shows superior body weight reduction and glycemic control compared to Semaglutide and Tirzepatide, widely applied in obesity, type 2 diabetes and metabolic syndrome laboratory studies.

    Our Retatrutide Product Competitive Advantages

    1. Ultra-high purity ≥99%

      Each batch passes HPLC and LC-MS mass spectrum identification to verify complete peptide sequence. Full COA, HPLC chromatogram, heavy metal and low-endotoxin test reports (third-party Janoshik testing available) are provided for all bulk orders; no degraded fragments or impurity residues.
    2. Advanced vacuum freeze-drying technology

      All moisture fully removed without preservatives, completely locks peptide biological activity. Lyophilized solid form resists hydrolysis and oxidation during long-distance air & sea cross-border shipping, maintaining stable potency with a 24-month shelf life.
    3. GMP clean-room sterile production

      Individually sealed single vial packaging to avoid cross-contamination. Custom private labels, bottle sizes and bulk bulk packing services are available for global resellers and lab suppliers.
    4. Excellent water solubility

      Rapidly dissolves in sterile bacteriostatic water to form clear transparent solution without sediment, convenient for precise laboratory dosage preparation for in vivo and in vitro research.
    5. Complete professional technical support

      We supply detailed reconstitution guide, storage specification, laboratory dosage reference and full batch traceability documents for all distributors.

    Storage & Reconstitution Instructions

    • Unopened lyophilized powder: Long-term storage at -20°C away from light and humidity, shelf life up to 24 months; short transit storage at 2–8°C is acceptable.
    • Recommended solvent: Sterile bacteriostatic water
    • Operation tip: Slowly solvent along the inner vial wall and swirl gently; violent shaking will cause peptide aggregation and activity loss.
    • Reconstituted liquid: Seal tightly and refrigerate at 2–8°C, finish all usage within 28 days; avoid repeated freeze-thaw cycles.

    Global Wholesale Cooperation Support

    • Flexible minimum order quantity & tiered large-volume discount for stable VIP long-term partners
    • Low-risk dedicated shipping lines for USA, EU, Brazil, Australia with reduced customs detention probability
    • Exclusive one-on-one VIP account manager, fast working-hour response and professional reshipping solutions for logistics issues


     About us


    Anhui Ruibang Trading Co., Ltd. was established with a clear mission: to simplify international trade for businesses of all sizes. We act as a bridge between manufacturers and global buyers, offering professional sourcing, quality inspection, order coordination, and logistics management.
    Our team brings years of experience in cross-border trade, supplier networks, and export documentation. We understand the challenges of international business — language barriers, quality control, shipping complexities — and we solve them with a client-first approach.
    At Ruibang Trading, we don’t just move goods; we build relationships. Whether you are looking for a reliable supplier, need help consolidating shipments, or want to expand your product line, we provide tailored solutions to meet your goals.
    Our Commitment: Integrity, efficiency, and transparency in every transaction. 


    Why choose us


              Our products are of reliable quality and sell well all over the world, with partners across many countries and regions. We have professional technical support and complete after-sales teams to promptly respond to all your inquiries and demands.

               We always strictly control product quality, adhere to honest business principles, and prioritize quality and service. With stable product strength and thoughtful services, we sincerely welcome global customers to negotiate cooperation and achieve win-win development together.

               We have been deeply engaged in the peptide industry for many years, serving as a source biotechnology factory integrating R&D, synthesis, production and sales.

              We strictly follow production and quality control standards, with the whole process adopting aseptic production and independent lyophilization and packaging. Our products feature stable appearance, good solubility and high activity retention.

              We support trial orders with small quantities, bulk orders and customized formulas, providing one-stop solutions for foreign trade supply and private customization needs.
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    ECHEMI Editorial Reference
    Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.

    Certificates
    • Retatrutide High purity Adamax Raw white Powder 5mg 10mg Certificates 1 TDS

    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

    CAS No.:

    2381089-83-2

    Molecular Formula:

    C221H342N46O68

    InChIKeys:

    MLOLQJNKXBNWFW-SAGGEDDASA-N

    Molecular Weight:

    4731.33

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

    Research
    Class:

    Triple agonist — GCGR, GIPR, GLP-1R

    Status:

    Investigational (Phase 3)

    Mechanism:

    Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

    EC50 (Human GCGR):

    5.79 nM

    EC50 (Mouse GIPR):

    0.191 nM

    EC50 (Mouse GLP1R):

    0.794 nM

    EC50 (Mouse GCGR):

    2.32 nM

    EC50 (Human GLP1R):

    0.775 nM

    EC50 (Human GIPR):

    0.0643 nM

    Source:

    Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

    Clinical Development:

    NCT04881760; NCT05882045; NCT06354660

    References
    ChEMBL:

    CHEMBL5095485

    DrugBank:

    DB18993

    KEGG DRUG:

    D12430

    PubChem:

    PubChem

    Disclaimer:

    Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

    Location:

    Hefei, Provincia de Anhui

    Year of Establishment:

    2026

  • Inquiry History
    6811 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Retatrutide 2381089-83-2

    3 MT Mar 28, 2026
    United Kingdom

    Retatrutide - 2381089-83-2

    1 G Feb 10, 2026
    United States

    Retatrutide CAS 2381089-83-2 10mg vial

    20 MT Mar 7, 2026
    United States

    Factory Retatrutide API 99% Purity CAS 2381089-83-2

    5 KG Nov 10, 2025
    United Kingdom

    Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA

    1 MT Mar 22, 2026
    United States

    2381089-83-2

    100 G Jul 14, 2026
    United States

    2381089-83-2

    100 G Feb 24, 2026
    United States

    2381089-83-2

    100 MT Dec 9, 2023
    United States

    Retatrutide 2381089-83-2

    200 MG May 16, 2026
    United Kingdom

    2381089-83-2 retatrutide

    300 MG Feb 13, 2026
    United States

    Retatrutide 2381089-83-2 wholesale

    500 MT Nov 3, 2023
    United States

    Retatrutide CAS 2381089-83-2 99%

    10 PCS Feb 21, 2026
    Poland

    CAS 2381089-83-2 (Custom Peptide)

    40 MT Apr 10, 2026
    Austria

    Peptide Retatruide CAS 2381089-83-2

    100 MT Apr 4, 2026
    Austria

    Retatrutide CAS 2381089-83-2 10mg vial

    20 PCS Feb 10, 2026
    United States

    Tirzepatide 99.9% Liquid 2381089-83-2 TeruiOP

    1 MT Sep 6, 2023
    United States

    Retatrutide/LY3437943/GIPR/GLP-1R 98% Powder 2381089-83-2 Senwayer

    1 G Sep 3, 2023
    United States

    GLP-1 / GIP Retatrutide cas 2381089-83-2

    1 MT Oct 16, 2024
    United States

    Retatrutide 99% High Quality CAS 2381089-83-2

    1 G Jan 23, 2026
    United States

    Injection Peptide Tirzepatide/Retatrutide/ Semaglutide Peptides CAS 2381089-83-2

    10  Oct 21, 2023
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