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High Quality Bronchogen 99%Freeze-dried powder In stock Minimum Order Hot Selling

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Unit Price:

$10/UNIT FOB

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CAS No.:

24305-27-9

Grade:

Research Grade

Content:

99.89%

Port:

Shenzhen

Brand:

Packaging:

vials/box

Price valid (until):

2027-01-31

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Xinhong Bio-Chem Co., Ltd.

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Retatrutide,Tirzepatide,Semaglutide,GHK-CU,NAD+,MOTS-C

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Basic Parameter Information

Full Name: Bronchogen Lung Tissue Regulatory Tripeptide

Amino Acid Sequence: H-Glu-Asp-Arg-OH

Molecular Formula: C₁₄H₂₆N₆O₈

Molecular Weight: 406.39 g/mol

CAS Number: Custom synthetic tissue bioregulator without universal public CAS registration number

Appearance: Sterile lyophilized white crystalline powder, individually sealed in separate vials (main specifications: 10mg / 20mg / 50mg)

Purity: ≥99% verified by HPLC detection, complete COA quality inspection documents are provided with every production batch

R&D Background: Bronchogen is a targeted short tripeptide bioregulator from the peptide gerontology research system, derived from the active functional fragments of pulmonary mucosal tissue endogenous polypeptides. This high-purity synthetic laboratory raw material is developed for bronchial epithelial cell cultivation, pulmonary barrier function testing, chronic respiratory inflammatory cell model research and age-related lung tissue degenerative mechanism exploration. It is widely used in respiratory cell biology, airway mucosal regeneration and pulmonary aging pathology laboratory projects.

2. Core Mechanism of Action

Bronchogen easily penetrates respiratory epithelial cell membranes and acts on gene regulatory segments related to lung tissue homeostasis, activating multi-layer mucosal protection and tissue repair signaling networks in in vitro culture systems:

Stimulate the proliferation and renewal capacity of primary bronchial epithelial precursor cells, maintain stable viable cell quantity during long-term cell incubation and slow the decline of mucosal cell vitality;

Upregulate the expression of mucous barrier structural proteins and tight junction related factors, consolidate the integrity of airway epithelial monolayer and reduce abnormal substance leakage under irritant stimulation;

Suppress the over-secretion of pro-inflammatory signaling factors in airway resident immune cells, rebuild a mild tissue microenvironment and alleviate continuous inflammatory erosion of bronchial mucosal structures;

Restrain the overexpression of tissue matrix degradation enzymes triggered by chronic stimulation, reduce excessive breakdown of extracellular support structures and prevent irreversible remodeling of airway tissue;

Enhance the expression of intracellular antioxidant proteins in lung epithelial cells, clear accumulated oxidative metabolites and relieve cellular senescence caused by long-term stress stimulation;

Optimize signal communication between bronchial epithelial cells and pulmonary stromal cells, balance metabolic activity of mixed lung tissue co-culture systems under simulated adverse environmental conditions.

3. Core Research Efficacy (For Research Laboratory Use Only)

Bronchial Epithelial Cell Culture & Airway Barrier Research

Core experimental probe for cultivating primary respiratory mucosal cells, suitable for quantitative detection of tight junction protein expression and mucosal barrier integrity test assays.

Chronic Respiratory Inflammation Cell Model Research

Key raw material for exploring persistent airway inflammatory injury pathways, supporting cell-level experiments simulating irritant-induced bronchial tissue damage.

Lung Tissue Anti-Senescence & Oxidative Protection Research

Auxiliary testing reagent for senescent pulmonary cell culture systems, applied to mechanistic analysis of oxidative damage relief and epithelial cell function restoration.

Airway Tissue Remodeling Regulatory Mechanism Research

Balance catabolic and anabolic signals of extracellular matrix, ideal for laboratory research on restraining abnormal airway structural fibrosis and reconstruction.

Mixed Pulmonary Tissue Co-Culture Microenvironment Research

Coordinate interactive regulatory signals between epithelial and stromal cells, supporting exploration of homeostasis maintenance mechanisms in lung local tissue microenvironment.

Supplied as sterile lyophilized white crystalline powder with HPLC-certified purity ≥99%, mainstream vial specifications include 10mg, 20mg and 50mg. Every batch is attached with full supporting documents covering COA, MSDS and HPLC chromatogram test records.

As a lung-specific short tripeptide laboratory reagent, Bronchogen integrates bronchial epithelial renewal promotion, airway barrier reinforcement, inflammatory balance regulation and anti-senescence protective effects. Its small molecular chain delivers excellent water solubility and stable cell permeability, maintaining consistent tissue-targeted regulatory activity across various in vitro respiratory epithelial and mixed lung tissue co-culture research systems.

It serves as indispensable research material for cell cultivation and tissue model experiments covering respiratory mucosal regenerative biology, airway inflammatory balance, pulmonary cell senescence and chronic airway tissue remodeling research.

Note: For laboratory research experimental use only, not approved for human oral intake or clinical therapeutic preparation application.

We maintain sufficient stable stock, complete export certification paperwork, door-to-door double clearance logistics service with full real-time shipment tracking available for all orders.

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ECHEMI Editorial Reference

Protirelin is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.
Protirelin is a tripeptide composed of L-pyroglutamyl, L-histidyl and L-prolinamide residues joined in sequence. It has a role as a human metabolite. It is a peptide hormone and a tripeptide.|Protirelin is the pharmaceutically available synthetic analogue of the endogenous peptide thyrotropin-releasing hormone (TRH). It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) and prolactin from the anterior pituitary. Although not currently available in any FDA-approved product, protirelin is a component of the TRH Test where it is used to test the response of the anterior pituitary gland in conditions such as secondary hypothyroidism and acromegaly.|A tripeptide that stimulates the release of THYROTROPIN and PROLACTIN. It is synthesized by the neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, TRH (was called TRF) stimulates the release of TSH and PRL from the ANTERIOR PITUITARY GLAND.

Certificates

Basic Info

Product Name:

TSH-releasing hormone

Other Name:

L-Prolinamide,5-oxo-L-prolyl-L-histidyl-;Thyrotropin-releasing factor;5-Oxo-L-prolyl-L-histidyl-L-prolinamide;L-Pyroglutamyl-L-histidyl-L-prolinamide;L-Pyroglutamyl-L-histidyl-L-proline amide;Synthetic TRH;Synthetic thyrotropin-releasing hormone;(Pyro)-L-glutamic acid-L-histidine-L-proline-NH2;Synthetic TSH-releasing hormone;Synthetic TSH-releasing factor;Synthetic thyrotropin-releasing factor;Lopremone;FDA 1725;Synthetic TRF;Protirelin;TSH-releasing factor;Thyroliberin;TRH;TRF;Thyrotropin-releasing hormone;Thyrotropic hormone-releasing factor;TSH-releasing hormone;Thyrotropic hormone-releasing hormone;Thyrotropic-releasing factor;TSH-RF;Thyroid-stimulating hormone-releasing factor;Thyrotropic releasing hormone;Rifathyroin;Ro 8-6270/9;Thyroid releasing hormone;Relefact TRH;Thyrefact;Rifotironin;Antepan;Prem;Thypinone;Stimu TSH;Abbott 38579;83: PN: US20090175821 PAGE: 403 claimed protein;252: PN: WO2010033207 SEQID: 378 claimed protein;9015-91-2;22365-17-9;22365-02-2;39422-15-6;77666-61-6

CAS No.:

24305-27-9

Molecular Formula:

C16H22N6O4

InChIKeys:

InChIKey=XNSAINXGIQZQOO-SRVKXCTJSA-N

Molecular Weight:

362.38

Exact Mass:

362.38

EC Number:

246-143-4

UNII:

5Y5F15120W

DSSTox ID:

DTXSID0023533

ATC Code:

V - Various

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

150

XLogP3:

-2.43

Appearance:

powder

Density:

1.5±0.1 g/cm3

Boiling Point:

942.1±65.0 °C at 760 mmHg

Flash Point:

523.6±34.3 °C

Refractive Index:

1.617

Water Solubility:

H2O: 10 mg/mL, clear, colorless

Storage Conditions:

−20°C

Vapor Pressure:

0mmHg at 25°C

Collision Cross Section:

181 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|184.12 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|187.07 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|179.2 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|182.4 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|184.5 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|183.2 Å² [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|183.2 Å² [M-2H+Na]-

See More TSH-releasing hormone Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Inhalation

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H332 Harmful if inhaled
Prevention	P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P317 Get medical help.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More TSH-releasing hormone Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Retatrutide,Tirzepatide,Semaglutide,GHK-CU,NAD+,MOTS-C

Location:
Block 1, No. 205, Tongbao Road, Jiangdong Street, Yiwu City, Jinhua City, Zhejiang Province (within Zhejiang Juzhiyun Holding Co., Ltd., on the 4th floor of 2 buildings)

Payment Terms:
TT against copy of documents,O/A,100% TT in advance

Total Employees:
101-200

Year of Establishment:
2026

Company Profile

Yiwu Xinhong Trading Co., Ltd. is a professional trading company engaged in the international supply and distribution of peptides, chemical raw materials.
Leveraging a reliable network of qualified manufacturers and strategic partners, we provide customers with high-quality products, competitive pricing, and efficient supply chain solutions. Our products are widely used in pharmaceutical research, biotechnology, chemical manufacturing, laboratory research, and various industrial applications.

With extensive experience in international trade, we are committed to helping customers source quality chemical products from China through professional procurement services, strict supplier selection, and reliable logistics support. We focus on building long-term partnerships by delivering consistent quality, responsive communication, and dependable service.

Main Products
Peptides
Chemical Raw Materials
Organic Chemicals
Inorganic Chemicals
Fine Chemicals
Our Advantages
Professional international trading services
Reliable supplier network
Competitive pricing and flexible sourcing
Strict quality control and supplier management
Fast response and efficient communication
Global export and logistics support
Business Scope

Global sourcing, international trade, import and export of chemical products, customized procurement solutions, and supply chain services.

Markets

Europe, North America, South America, Southeast Asia, the Middle East, and other international markets.

Yiwu Xinhong Trading Co., Ltd. is committed to providing professional chemical sourcing solutions and creating long-term value for customers worldwide. We look forward to establishing mutually beneficial partnerships with clients across the globe.

Business Type: Trading Company
Company Name: Yiwu Xinhong Trading Co., Ltd.
Main Business: Peptides, Chemical Raw Materials
Market: Global

Inquiry History

7 Inquiries

Country	Product	Purchase Quantity	Date Posted
Brazil	TRH Thyrotropin	10 MT	Mar 5, 2026
Italy	Thyrotropin	200 MG	Nov 22, 2024
Netherlands	Livagen	1 G	Apr 26, 2026
United States	TRH (Thyrotropin-Releasing Hormone)	20 MG	Jul 23, 2025
Thailand	Bronchogen	100	Apr 23, 2025
Italy	Protirelin	100 MG	Nov 7, 2024
United States	Protirelin Acetate	10 KG	Nov 15, 2023

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