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Home > Active Pharmaceutical Ingredients > Inhibitor Drugs > Tranylcypromine sulfate for Sale > Trans-2-Phenylcyclopropylamine Hemisulfate Salt 13492-01-8
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Trans-2-Phenylcyclopropylamine Hemisulfate Salt 13492-01-8

2 Inquiries

Unit Price:

$45-56/MT FOB

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CAS No.:

13492-01-8

Grade:

Industrial Grade

Content:

99%

Port:

sh

Brand:

orient

Packaging:

1KG, 5KG, 25KG

Price valid (until):

2028-08-18

Company Type:
Trader
Location:
China
Qualification:
Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Product Name: Dermorphin
    Synonyms: DERMORPHIN ACETATE;L-Tyr-D-Ala-L-Phe-Gly-L-Tyr-L-Pro-L-Ser-NH2;Tyrosyl-alanyl-phenylalanyl-glycyl-tyrosyl-prolyl-serinamide;Dermorphin trifluoroacetate salt;Dermorphin Powder;(2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide;Dermorphin HAc;(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-1-carbamoyl-2-hydro
    CAS: 77614-16-5
    MF: C40H50N8O10
    MW: 802.87
    EINECS: 202-853-6
    Product Categories: 77614-16-5
    Mol File: 77614-16-5.mol
    Shop Dermorphin 77614-16-5 API-Detailed Image 1

    Dermorphin Chemical Properties
    Melting point  157-159 °C
    Boiling point  1323.8±65.0 °C(Predicted)
    density  1.363±0.06 g/cm3(Predicted)
    storage temp.  -20°C
    solubility  Soluble in DMSO
    form  powder
    pka 9.83±0.15(Predicted)
    color  white to off-white
    Sequence H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2
    InChIKey FHZPGIUBXYVUOY-VWGYHWLBSA-N
    SMILES C(N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N)(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](C)NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)CC1C=CC=CC=1)CC1C=CC(O)=CC=1

    Safety Information
    WGK Germany  3
    MSDS Information


    Dermorphin Usage And Synthesis
    Structure Dermorphin does not contain the common N-terminal sequence for the traditional endogenous  peptides (Tyr–Gly–Gly–Phe), and its sequence is completely different from those of the endomorphins, which were identified as endogenous μ- peptides that also do not contain the common sequence. Interestingly, DM contains D-alanine (a D-isomer amino acid) in its sequence. The primary structure of dermorphin is YDAFGYPS-NH2.
    Description Dermorphin was first isolated from the skin of the skin of South American frogs of the genus Phyllomedusa.  It is a high potency natural opiate peptide that binds selectively to mu- receptors.
    Uses A mu- receptor agonist
    Definition ChEBI: Dermorphin is an oligopeptide.
    Side effects Like μ-opiate agonists, dermorphins produce antinociception and also catalepsy, respiratory depression, constipation, tolerance, and dependence, although at a lower degree than   does[1].
    in vitro Dermorphin, a peptide isolated from the skin of Phyllomedusa frogs and the peptide receptor (NOP) component by the endogenous agonist nociceptin/orphanin FQ (N/OFQ). In displacement binding studies at CHOhMu, Dermorphin and DeNo displac the binding of [3H]-DPN in a concentration dependent and saturable manner. Dermorphin displays an affinity of 7.17, while N/OFQ fails to displace [3H]-DPN at the Delta receptor. Dermorphin and DeNo stimulate the binding of GTPγ[35S] in a concentration dependent and saturable manner at the Mu receptor.
    References [1] Negri, L. P. Melchiorri and R. Lattanzi. “ and Bv8 Peptides.”Handbook of Biologically Active Peptides (Second Edition) 2013:376-383.

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    Q1:Do you provide sample?

    A: Yes, we can provide free sample, you only need pay the shipping cost.

    Q2: What is the lead time?

    A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

    Q3: How can I buy? What is the payment method?

    A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer, 

    Q4:What if there are quality issues?

    A:We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

    ECHEMI Editorial Reference
    Tranylcypromine hemisulfate is an irreversible, nonselective MAO inhibitor used in the treatment of depression.
    A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)

    Basic Info
    Product Name:

    Tranylcypromine sulfate

    Other Name:

    Cyclopropanamine,2-phenyl-,(1R,2S)-rel-,sulfate (2:1);Cyclopropylamine,2-phenyl-,sulfate (2:1),trans-(±)-;Cyclopropanamine,2-phenyl-,trans-(±)-,sulfate (2:1);Parnate;Tranylcypromine sulfate;dl-Tranylcypromine sulfate;Tylciprine;trans-2-Phenylcyclopropanamine sulfate (2:1);Cyclopropanamine,2-phenyl-,trans-,sulfate (2:1);Parnetil;trans-2-Phenylcyclopropylamine hemisulfate;1949-18-4;7081-36-9

    CAS No.:

    13492-01-8

    Molecular Formula:

    C9H11N.1/2H2O4S

    InChIKeys:

    InChIKey=BTHVHSMCHJCPFU-LZPPVNAUNA-N

    Molecular Weight:

    364.46

    Exact Mass:

    364.14567842

    EC Number:

    236-807-1

    Categories:

    Inhibitor Drugs

    Characteristics
    Density:

    1.065g/cm3

    Flash Point:

    90.8ºC

    Water Solubility:

    soluble in water; very slightly soluble in ethanol (96%) and in ether .

    Storage Conditions:

    2-8°C

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 2, Oral

    Acute toxicity - Category 3, Dermal

    Acute toxicity - Category 3, Inhalation

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H300 Fatal if swallowed

    H311 Toxic in contact with skin

    H331 Toxic if inhaled

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P316 Get emergency medical help immediately.

    P361+P364 Take off immediately all contaminated clothing and wash it before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    Storage

    P405 Store locked up.

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    pharmaceutical intermediates,peptides,electronic chemicals

    Location:

    Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

    Payment Terms:

    100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    51-100

    Year of Establishment:

    2024

    A reliable supplier is like insurance.

    We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals,food additives, and other fine chemical products.
    Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

    Website: orientchem.cc
    Email: scarlett@orientchem.cc
    WhatsApp: +86 17753254221

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Sweden

    Trans-2-Phenylcyclopropylamine Hemisulfate Salt

    10 G Aug 31, 2026
    Russia

    Trans-2-Phenylcyclopropylamine Hemisulfate Salt

    10 G Aug 31, 2026
    Post an enquiry for this product
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