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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Semaglutide for Sale > Semaglutide GLP-1 Peptide (99%) - Trusted for Laboratory and Research Use 910463-68-2
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Semaglutide GLP-1 Peptide (99%) - Trusted for Laboratory and Research Use 910463-68-2

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Unit Price:

$69/UNIT FOB

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CAS No.:

910463-68-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

zhongma

Packaging:

20mg*10vials 30mg*10vials

Price valid (until):

2027-06-30

Company Type:
Trader
Location:
China
Qualification:
Main Products:

GLP-1,Retatrutide,Tirzepatide,Peptides

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    -Sales manager:sunny 

    -whatsapp:+86 18830992163 
    -Email:sunny@hzzmtrade.cn 

    Wholesale Price 20mg 30mg  Semaglutide Weight Loss CAS: 910463-68-2



      Product Detail  


    --What is Semaglutide?

    Semaglutide is a peptide compound that has attracted significant attention in biochemical and metabolic research. Its molecular structure is related to liraglutide and incorporates specific structural modifications designed to enhance molecular stability.

    One structural modification involves the substitution of Gly at position 2 with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib). Another modification involves the attachment of an 18-carbon fatty-acid moiety to Lys-26 through a spacer and linker structure.

    These structural characteristics contribute to its stability and interaction with albumin. Semaglutide is widely studied in research involving GLP-1 receptor activity, metabolic pathways, receptor signaling, and related biochemical mechanisms.

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    --Description 

    Product name semaglutide CAS NO. 910463-68-2
     Purity 99% Molecular weight 4113.57754
    Appearance White powder Molecular Formula C187H291N45O59
    Storage Store at -20°C Function Metabolic Research
    Specifications 20mg/vial MNQ 1 box of 10 vials


     Drug characteristics 



    • Long-acting effect: Semaglutide binds to albumin, prolonging its half-life and enabling once-weekly dosing, which significantly improves patient adherence.
    • Glycemic control mechanism:
      1. (1)Supports research on glucose-dependent metabolic pathways and glucagon regulation.
      2. (2)Delays gastric emptying, reducing postprandial blood glucose fluctuations.
    • Weight loss effect: Suppresses appetite via the central nervous system, reduces food intake, and increases satiety, aiding in weight management.
    • Cardiovascular protection: Reduces the risk of major adverse cardiovascular events (MACE), including cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke.


    Product Application 


    1. 1.Metabolic pathway research
    2. 2.Receptor signaling studies
    3. 3.Glucose-related metabolic research
    4. 4.Lipid metabolism research
    5. 5.Hepatic metabolic pathway studies
    6. 6.Energy metabolism research
    7. 7.Biochemical mechanism studies
    8. 8.Appetite-related signaling research

    Indications: Type 2 diabetes: Used to improve glycemic control, particularly in patients who do not respond adequately to metformin or other oral antidiabetic agents.

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     Why choose us? 



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        Company Profile  


    Our company is a modern advanced enterprise specializing in production and exportation of APIs, Pharmaceutical intermediates, plant extracts etc. Our products are widely used in medicine, health care products, cosmetics, nutritional supplements and food additives areas. Those products of both quality and technical content have reached the domestic advanced level. Since its establishment, the company has attached great importance to the team training and technical reform. Our modern production equipment guarantees for a fast and effective production with a superior degree of accuracy throughout the whole production line, everything is done in-house, processing, extraction, packaging and transportation of all links, ensuring maximum quality and efficiency. We are constantly research and development new ingredients and innovative new products, have earned the respect & Admiration from the worldwide customers. After years of continuous development, company has been accumulated rich experience in international trade and customer resources, established a stable customer base and perfect marketing service network. In addition, the company has established long-term technical cooperation with experts and professors from many universities and research institutes in the province.

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    ECHEMI Editorial Reference

    Semaglutide (CAS: 910463‑68‑2) is a synthetic lipid‑modified peptide analogue, consisting of a 31‑amino‑acid backbone with a covalently attached C18 fatty di‑acid side‑chain via a hydrophilic spacer. It shares 94% amino‑acid sequence homology with native human GLP‑1 peptide. The substance appears as white to almost white hygroscopic powder, with molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and molecular weight of 4113.58 g/mol. Structural modifications grant it resistance against DPP‑4 enzymatic degradation and enable reversible binding to serum albumin, contributing to its extended in‑vivo half‑life property.

    Basic Info
    Product Name:

    Semaglutide

    Other Name:

    Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide

    CAS No.:

    910463-68-2

    Molecular Formula:

    C187H291N45O59

    InChIKeys:

    DLSWIYLPEUIQAV-CCUURXOWSA-N

    Molecular Weight:

    4113.57754

    Exact Mass:

    4113.122087 g/mol

    EC Number:

    203-405-2

    Color/Form:

    White to off-white

    Characteristics
    PSA:

    1650 Ų

    XLogP3:

    5.44520

    Critical Temperature & Pressure:

    Store at -20°C

    Research
    Class:

    GLP-1R agonist

    Status:

    FDA-approved (Ozempic / Wegovy / Rybelsus)

    Mechanism:

    Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

    Activity note:

    Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

    Source:

    Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

    Clinical Development:

    NCT03548935; NCT03552757; NCT01720446; NCT02692716

    FDA:

    Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

    References
    ChEMBL:

    CHEMBL2108724

    DrugBank:

    DB13928

    KEGG DRUG:

    D10025

    PubChem:

    PubChem

    Disclaimer:

    Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    GLP-1,Retatrutide,Tirzepatide,Peptides

    Location:

    Room A008, 704#, Building 11, Shiliu Street Block, Liangzhu Subdistrict, Yuhang District, Hangzhou City, Zhejiang Province

    Payment Terms:

    TT against copy of documents,100% TT in advance

    Average lead Time:

    1

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2025

  • Inquiry History
    490 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Weight Loss Semaglutide intermediate 99% White powder COA High Quality peptide GLP-1 910463-68-2

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    Dec 5, 2023
    United States

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    United States

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    2 KG Oct 21, 2023
    China

    Semaglutide CAS 910463-68-2

    1 KG Apr 16, 2026
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    50 MT Nov 13, 2023
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    1000 G Sep 23, 2023
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    China

    Semaglutide Tirzepatide for Weight Loss CAS: 910463-68-2 Retatrutide Cagrilintide

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