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Hexamethylphosphoramide

Unit Price:

$28/KG EXW

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CAS No.:

680-31-9

Grade:

Pharma Grade

Content:

99%

Brand:

DAHAI BIOCHEM

Packaging:

25kg/Cardboard Drum

Price valid (until):

2026-12-31

Company Type:
Trader
Location:
China
Qualification:
Main Products:

HARD FAT

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    "[Product Overview & Applications]
    Hexamethylphosphoramide (CAS NO.: 680-31-9) is supplied under stringent quality supervision by DAHAI BIOCHEM. It is a high-grade chemical intermediate widely utilized in fine chemical manufacturing, organic synthesis research, and active pharmaceutical ingredient (API) development. The product features exceptional chemical purity, reliable batch-to-batch consistency, low residual impurities, and high reaction stability, ensuring maximum efficiency and reliability in customer manufacturing processes.

    [Technical Specifications & Parameters]
    - Product Name: Hexamethylphosphoramide
    - CAS Registry Number: 680-31-9
    - Classification: Pharmaceutical Intermediates & Fine Chemicals
    - Assay / Purity: >= 99.0%
    - Physical Form / Appearance: White Powder
    - Quality Grade: Pharma Grade
    - Manufacturer / Brand: DAHAI BIOCHEM
    - Standard Export Package: 25kg/Cardboard Drum
    - Minimum Order Quantity (MOQ): 1 KG

    [Quality Standards & Storage Conditions]
    1. Quality Standards: Conforms strictly to enterprise and international industrial quality standards. Every production lot undergoes rigorous analytical testing including HPLC, GC, or titration analysis with full batch documentation provided.
    2. Storage & Handling: Store in tightly sealed original containers in a cool, dry, and well-ventilated warehouse. Keep strictly away from direct sunlight, open flames, high temperatures, moisture, and incompatible substances.
    3. Export Logistics & Packaging: Supplied in robust standard export packaging to guarantee integrity during global maritime and air freight. Flexible OEM and customized commercial packaging are available upon inquiry."

    ECHEMI Editorial Reference
    It appears as colorless transparent flammable liquid with a medium ammonia flavor. It is soluble in water, polar and non-polar solvents.
    Hexamethylphosphoramide is a clear colorless to light amber liquid with a spicy odor. (NTP, 1992)|COLOURLESS MOBILE LIQUID.|Clear, colorless to light amber liquid with an aromatic or mild, amine-like odor.|Clear, colorless liquid with an aromatic or mild, amine-like odor. [Note: A solid below 43°F.]
    Hexamethylphosphoramide is a clear colorless to light amber liquid with a spicy odor. (NTP, 1992)|Hexamethylphosphoric triamide is a phosphoramide. It has a role as a mutagen and an insect sterilant.|Hexamethylphosphoramide is no longer used in large quantities in the United States. No information is available on the acute (short-term), chronic (long-term), reproductive, developmental, or carcinogenic effects of hexamethylphosphoramide in humans. Acute animal studies have reported effects on the kidneys and lungs from oral exposure to hexamethylphosphoramide, while chronic oral studies in animals have reported an increased incidence of lung disease. An increased incidence of nasal tumors from inhalation exposure to hexamethylphosphoramide was reported in rats. EPA has not classified hexamethylphosphoramide for carcinogenicity; however, the International Agency for Research on Cancer (IARC) has classified it as a Group 2B, possible human carcinogen.|Hexamethylphosphoramide is a clear, colorless liquid with an aromatic odor that emits toxic fumes of phosphorous oxides and nitrogen oxides when heated to decomposition. Hexamethylphosphoramide is used as a stabilizer against thermal degradation in polystyrene and is used as a solvent in research laboratories. Exposure to this substance irritates the eyes, skin and respiratory-tract. Hexamethylphosphoramide is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals. (NCI05)|A chemosterilant agent that is anticipated to be a carcinogen.

    Basic Info
    Product Name:

    Hexamethylphosphoramide

    Other Name:

    Phosphoric triamide,N,N,N′,N′,N′′,N′′-hexamethyl-;Phosphoric triamide,hexamethyl-;N,N,N′,N′,N′′,N′′-Hexamethylphosphoric triamide;ENT 50,882;Hempa;Hexametapol;Hexamethylphosphoramide;Hexamethylphosphoric acid triamide;Hexamethylphosphoric triamide;Hexamethylphosphorotriamide;HPT;Phosphoric tris(dimethylamide);Phosphoryl hexamethyltriamide;Tris(dimethylamino)phosphine oxide;Hexamethylorthophosphoric triamide;HMPA;Phosphoric hexamethyltriamide;Phosphoric acid hexamethyltriamide;N,N′,N′′-Hexamethylphosphoramide;Eastman Inhibitor HPT;HMPTA;HMPT;Hexamethyltriamidophosphate;NSC 113131;NSC 7967;Light Stabilizer HPT;[Bis(dimethylamino)phosphoryl]dimethylamine;Hexamethylphosporic triamide;24992-55-0;51557-01-8

    CAS No.:

    680-31-9

    Molecular Formula:

    C6H18N3OP

    InChIKeys:

    InChIKey=GNOIPBMMFNIUFM-UHFFFAOYSA-N

    Molecular Weight:

    179.2

    Exact Mass:

    179.20

    EC Number:

    211-653-8

    UNII:

    M42TU5843Z

    ICSC Number:

    0162

    NSC Number:

    113131|7967

    UN Number:

    2810|3082

    DSSTox ID:

    DTXSID6020694

    NCI Thesaurus Code:

    C44390

    Color/Form:

    COLORLESS, MOBILE LIQUID|Clear, colorless liquid [Note: A solid below 43 degrees F].

    HScode:

    29299090

    Characteristics
    PSA:

    26.8

    XLogP3:

    0.77930

    Appearance:

    Hexamethylphosphoramide is a clear colorless to light amber liquid with a spicy odor. (NTP, 1992)

    Density:

    1.03 g/cm3 @ Temp: 20 °C

    Melting Point:

    5-7 °C

    Boiling Point:

    233 °C @ Press: 760 Torr

    Flash Point:

    222 °F

    Refractive Index:

    n20/D 1.459(lit.)

    Water Solubility:

    Miscible

    Storage Conditions:

    Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ) that bears appropriate label. An inventory should be kept, showing quantity of carcinogen & date it was acquired Facilities for dispensing should be contiguous to storage area.

    Vapor Pressure:

    0.07 mm Hg ( 25 °C)

    Vapor Density:

    6.18 (vs air)

    Toxicity:

    LD50 in male, female rats (mg/kg): 2650, 3360 orally (Gaines)

    Flammability characteristics:

    Class IIIB Combustible Liquid: Fl.P. at or above 200°F.

    Odor:

    AROMATIC ODOR

    Experimental Properties:

    DOES NOT HYDROLYZE IN ALKALINE MEDIA BUT HYDROLYZES SLOWLY IN ACIDS

    Air and Water Reactions:

    Water soluble.

    Reactive Group:

    Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters

    Reactivity Profile:

    HEXAMETHYLPHOSPHORAMIDE may react with strong oxidizing agents and strong acids (NTP, 1992). Susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

    Flammable Limits:

    Class IIIB Combustible Liquid: Fl.P. at or above 200°F.

    Hazard Identification

    Classification of the substance or mixture

    Germ cell mutagenicity, Category 1B

    Carcinogenicity, Category 1B

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H340 May cause genetic defects

    H350 May cause cancer

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Ventilation along the floor.PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. Chemical Carcinogens

  • Seller Information
    Business Type:

    Trader

    Main Products:

    HARD FAT

    Location:

    BUILDING 4,NO.571, STR.19,BAIYANG DISTRICT, HANGZHOU,CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    5-10

    Year of Establishment:

    2025

  • Country Product Purchase Quantity Date Posted
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