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Elamipretide api

Name: Elamipretide api
Brand: Elamipretide api
SKU: pr2609111997
Price: 100 USD
Availability: InStock

99 Inquiries

Unit Price:

$100-101/G FOB

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CAS No.:

736992-21-5

Grade:

Pharmaceutical Grade

Content:

99.9%

Port:

shanghai

Brand:

Elamipretide api

Packaging:

BOTTLE

Price valid (until):

2026-10-11

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Product Name:	Elamipretide
Synonyms:	Elamipretide;Elamipretide (TFA salt);SS-31;MTP-131;BENDAVIA;Bendavia);Elamipretide (SS-31;ELAMIPRETIDE, >99%;Elamipretide,MTP-131,RX-31,SS-31, >99%;Elamipretide (MTP-131
CAS:	736992-21-5
MF:	C32H49N9O5
MW:	639.79
EINECS:	205-858-1
Product Categories:	736992-21-5
Mol File:	736992-21-5.mol

Elamipretide Chemical Properties

density	1.34±0.1 g/cm3(Predicted)
solubility	Methanol (Slightly), Water (Slightly)
pka	10.10±0.25(Predicted)
form	Solid
color	White to Off-White
Sequence	H-d-Arg-dimethylTyr-Lys-Phe-NH2
Stability:	Hygroscopic
InChIKey	SFVLTCAESLKEHH-WKAQUBQDSA-N
SMILES	C(N)(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=C(C)C=C(O)C=C1C)NC(=O)[C@@H](CCCNC(N)=N)N

Safety Information

MSDS Information

Elamipretide Usage And Synthesis

Description	Elamipretide, also known as MTP 131, is a mitochondria-targeted peptide antioxidant. Elamipretide decreases inflammation and protect against a variety of neurological illnesses. Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice. Elamipretide Promotes Mitophagosome Formation and Prevents Its Reduction Induced by Nutrient Excess in INS1 β-cells.
Uses	D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide-d5 Trifluoroacetic Acid Salt is labelled D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide (A769700) which is a mitochondrial-targeted compound that re-energizes ischemic mitochondria by interacting with cardiolipin. It is a cell-permeable antioxidant peptide.
Mechanism of action	Elamipretide can inhibit the production of pathogenic ROS (reactive oxygen species) and restore mitochondrial ATP synthesis. Currently, the most accepted mechanism for these two actions is the direct interaction between Elamipretide and cardiolipin.
Clinical Use	Barth syndrome is an ultra-rare genetic condition characterized by cardiac abnormalities leading to exercise intolerance, muscle weakness, debilitating fatigue, heart failure, recurrent infections, and delayed growth. There are currently no FDA- or EMA-approved therapies for patients with Barth syndrome. Elamipretide has an Orphan Drug, Fast Track and Rare Pediatric Designation from the FDA and Orphan Drug Designation from the EMA for treating Barth syndrome.
Side effects	Side effects of elamipretide include: Mild redness or itching at the in site Headache Dizziness
Description	Elamipretide Synthetic is a single, non-glycosylated polypeptide chain containing 4 amino acids, having a molecular mass of 640 Dalton and a Molecular formula of C₃₂H₄₉N₉O_{5 .}

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Items	Specifications

ECHEMI Editorial Reference

Elamipretide has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy.
Elamipretide, also known as MTP 131, is a mitochondria-targeted peptide antioxidant. Elamipretide decreases inflammation and protect against a variety of neurological illnesses. Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice. Elamipretide Promotes Mitophagosome Formation and Prevents Its Reduction Induced by Nutrient Excess in INS1 β-cells.
Elamipretide Synthetic is a single, non-glycosylated polypeptide chain containing 4 amino acids, having a molecular mass of 640 Dalton and a Molecular formula of C32H49N9O5 .

Basic Info

Product Name:

Elamipretide

Other Name:

D-Arginyl-2,6-diMethyl-L-tyrosyl-L-lysyl-L-phenylalaninaMide;Elamipretide;L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-;Elamipretide (TFA salt);SS-31;MTP-131;BENDAVIA;Bendavia);Elamipretide (SS-31;ELAMIPRETIDE, >99%

CAS No.:

736992-21-5

Molecular Formula:

C32H49N9O5

InChIKeys:

SFVLTCAESLKEHH-WKAQUBQDSA-N

Molecular Weight:

639.79

Exact Mass:

639.38566570

EC Number:

205-858-1

UNII:

87GWG91S09

DSSTox ID:

DTXSID50471988

Color/Form:

White to Off-White

Categories:

Bulk Drug Intermediates

Characteristics

Density:

1.34±0.1 g/cm3(Predicted)

PKA:

10.10±0.25(Predicted)

Research

Class:

Mitochondria-targeted tetrapeptide (Szeto-Schiller peptide)

Status:

FDA-approved (Forzinity) — Accelerated Approval 2025

Mechanism:

A cell-permeable, synthetic tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) that selectively concentrates in the inner mitochondrial membrane and reversibly binds to cardiolipin, a phospholipid essential for electron transport chain (ETC) function. By stabilizing cardiolipin, SS-31 restores mitochondrial bioenergetics, reduces cytochrome c peroxidase activity, and prevents oxidative damage in cells with impaired mitochondrial function.

Activity note:

SS-31 does not act via traditional receptor agonism. It binds cardiolipin with high selectivity in the inner mitochondrial membrane. Functional EC₅₀ values are context-dependent (cell type, stress model). Key electrophysiology studies report mitochondrial membrane potential restoration at nanomolar concentrations.

Source:

Szeto HH, et al. AAPS J. 2006;8(2):E277-E283. Birk AV, et al. J Am Soc Nephrol. 2014;25(6):1157-1169.DOI

Clinical Development:

NCT03098797; NCT02814097; NCT02976038; NCT03354065

FDA:

Forzinity (approved 2025-09-19)

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

FDA: Forzinity (NDA 215244) — Accelerated Approval 2025; Genetics in Medicine: TAZPOWER Phase 2/3 results (Thompson et al. 2020); Drugs: Elamipretide First Approval (Springer 2025)

Disclaimer:

Elamipretide (Forzinity) is FDA-approved under accelerated approval for Barth syndrome. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Elamipretide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

99 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	SS-31 (Elamipretide MTP-131) CAS 736992-21-5 99% White Powder XO	10	Oct 22, 2023
Canada	SS-31 (Elamipretide MTP-131) CAS 736992-21-5 99% White Powder XO	1	Sep 28, 2023
United States	SS-31	500 MG	Feb 20, 2026
Philippines	Elamipretide	100 MG	Mar 17, 2026
Philippines	Elamipretide / SS-31	5 G	Mar 16, 2026
Kazakstan	SS-31	500 MG	May 22, 2026
Malaysia	ss31	20 MG	Aug 12, 2026
Canada	Ss31	1 G	Jul 24, 2026
Turkey	SS-31 (Elamipretide MTP-131) CAS 99% White Powder	100 G	Jun 28, 2026
United States	Elamipretide SS31	460 MG	Jun 18, 2026
United States	SS31	50 MG	Jun 3, 2026
United Kingdom	SS-31 Lyophilised in vacuum sealed sterile vial	500 G	Jun 2, 2026
Brazil	ELAMIPRETIDE	1000 MG	May 28, 2026
United States	SS31	30 MG	May 27, 2026
United States	SS31	25 MG	May 26, 2026
United States	Ss31	5 MG	May 7, 2026
United States	High-purity raw material Elamipretide/SS-31	100 MG	May 3, 2026
United States	Ss-31 Elamipretide	5 PCS	Apr 19, 2026
United States	SS-31	100 G	Apr 18, 2026
United States	ss 31	10 MT	Apr 8, 2026

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Elamipretide api

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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