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SS-31 (Elamipretide)

105 Inquiries

Unit Price:

$190-220/G FOB

Get Latest Price
CAS No.:

736992-21-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shenzhen

Brand:

Zhaokebio

Packaging:

1g/vial, 5g/vial, 25g/drum

Sample Available:

Yes

Price valid (until):

2027-01-01

Company Type:
Trader
Location:
China
Payment Terms:
100% TT in advance
Average Lead Time:
30 days
Qualification:
Main Products:

Peptide API

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


    • SS-31 (Elamipretide) Peptide Powder, ≥99% HPLC, Research Grade

      SS-31 (Elamipretide) is a synthetic tetrapeptide supplied as a white lyophilized powder. It is intended as a research chemical for biochemistry and molecular biology studies. Manufactured under strict quality control, each batch is tested by HPLC to ensure purity ≥99%.

      Key Specifications:

      Product Name: SS-31 (Elamipretide) CAS No.: 736553-76-9 Sequence: D-Arg-Dmt-Lys-Phe-NH2 Molecular Formula: C27H36N8O5 Molecular Weight: 552.63 g/mol Purity: ≥99.0% (HPLC) Appearance: White lyophilized powder Solubility: Soluble in water Form: Bulk powder in sealed packaging Storage: Store in a cool, dry place, protected from light and moisture

      Applications: Molecular biology and biochemistry research Peptide API development and formulation studies

      Quality & Documentation: Manufactured under strict quality control with each batch released with COA (Certificate of Analysis) and HPLC chromatogram.

      Packaging & Supply: Available in 1g/vial, 5g/vial and 25g/drum (bulk packaging on request). MOQ: 1g. Small-scale trial orders and bulk production both available. DDP shipping to most destinations worldwide.

    Items Specifications
    Purity 99%
    CAS 736992-21-5
    Product Name SS-31 (Elamipretide)
    ECHEMI Editorial Reference
    Elamipretide has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy.
    Elamipretide, also known as MTP 131, is a mitochondria-targeted peptide antioxidant. Elamipretide decreases inflammation and protect against a variety of neurological illnesses. Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice. Elamipretide Promotes Mitophagosome Formation and Prevents Its Reduction Induced by Nutrient Excess in INS1 β-cells.
    Elamipretide Synthetic is a single, non-glycosylated polypeptide chain containing 4 amino acids, having a molecular mass of 640 Dalton and a Molecular formula of C32H49N9O5 .

    Basic Info
    Product Name:

    Elamipretide

    Other Name:

    D-Arginyl-2,6-diMethyl-L-tyrosyl-L-lysyl-L-phenylalaninaMide;Elamipretide;L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-;Elamipretide (TFA salt);SS-31;MTP-131;BENDAVIA;Bendavia);Elamipretide (SS-31;ELAMIPRETIDE, >99%

    CAS No.:

    736992-21-5

    Molecular Formula:

    C32H49N9O5

    InChIKeys:

    SFVLTCAESLKEHH-WKAQUBQDSA-N

    Molecular Weight:

    639.79

    Exact Mass:

    639.38566570

    EC Number:

    205-858-1

    UNII:

    87GWG91S09

    DSSTox ID:

    DTXSID50471988

    Color/Form:

    White to Off-White

    Characteristics
    Density:

    1.34±0.1 g/cm3(Predicted)

    PKA:

    10.10±0.25(Predicted)

    Research
    Class:

    Mitochondria-targeted tetrapeptide (Szeto-Schiller peptide)

    Status:

    FDA-approved (Forzinity) — Accelerated Approval 2025

    Mechanism:

    A cell-permeable, synthetic tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) that selectively concentrates in the inner mitochondrial membrane and reversibly binds to cardiolipin, a phospholipid essential for electron transport chain (ETC) function. By stabilizing cardiolipin, SS-31 restores mitochondrial bioenergetics, reduces cytochrome c peroxidase activity, and prevents oxidative damage in cells with impaired mitochondrial function.

    Activity note:

    SS-31 does not act via traditional receptor agonism. It binds cardiolipin with high selectivity in the inner mitochondrial membrane. Functional EC₅₀ values are context-dependent (cell type, stress model). Key electrophysiology studies report mitochondrial membrane potential restoration at nanomolar concentrations.

    Source:

    Szeto HH, et al. AAPS J. 2006;8(2):E277-E283. Birk AV, et al. J Am Soc Nephrol. 2014;25(6):1157-1169.DOI

    Clinical Development:

    NCT03098797; NCT02814097; NCT02976038; NCT03354065

    FDA:

    Forzinity (approved 2025-09-19)

    References
    ChEMBL:

    CHEMBL3833370

    DrugBank:

    DB11981

    KEGG DRUG:

    D10925

    PubChem:

    PubChem

    Disclaimer:

    Elamipretide (Forzinity) is FDA-approved under accelerated approval for Barth syndrome. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptide API

    Location:

    Room A207-208, Building A, No.3 Branch Park, Leibo Zhongcheng Life Science Park, Pingshan District, Shenzhen, Guangdong, China, 518118

    Payment Terms:

    100% TT in advance

    Average lead Time:

    30 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2025

    Company Certificates
    • Shenzhen Zhaoke Biotechnology Co., Ltd.Business Certificate Business Certificate

    Peptide API Manufacturer & Supplier in China | Cosmetic Peptides | Custom Peptide Synthesis
    Company Introduction
    Shenzhen Zhaoke Biotechnology Co., Ltd. (Zhaoke Biotech), founded in 2025 and based in Shenzhen, China, is a peptide API manufacturing and sourcing company serving global B2B customers. We specialize in peptide raw materials, cosmetic peptides, pharmaceutical peptide APIs, research peptides, bioactive ingredients, and custom peptide synthesis.
    Our portfolio covers 496+ peptide products and related raw materials across six categories: cosmetic, pharmaceutical, nutrition, sports & fitness, personal care, and pet care. Our main product lines include:
    GLP-1 and metabolic peptide raw materials: Semaglutide, Tirzepatide, Retatrutide, Cagrilintide, Mazdutide, Survodutide, and related peptides.
    Cosmetic and personal-care peptides: GHK-Cu (Copper Tripeptide-1), AHK-Cu, Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8, Acetyl Octapeptide-3 (SNAP-8), Syn-AKE, and other anti-wrinkle, repair, brightening, hair, scalp, and lash-care peptides.
    Bioactive ingredients: NMN, NAD+, Glutathione, Ectoin, Alpha-Arbutin, Niacinamide, Sodium Hyaluronate, and selected complementary actives.
    Research and custom peptides: Catalog peptides, modified peptides, and specification-based custom synthesis for laboratory and professional applications.
    We combine in-house R&D, pilot-scale, and QC capabilities with a manufacturing partner network. For defined product lines, we support solid-phase peptide synthesis (SPPS), preparative HPLC purification, lyophilization, and analytical testing. For projects requiring GMP production, we coordinate with GMP manufacturing partners. The production model, grade, specification, and available regulatory documentation are confirmed for each product and project.
    Quality documentation includes batch-specific COA. HPLC purity, LC-MS identity, water content, and other analytical items are provided according to the agreed product specification. SDS/MSDS, TDS, customized specifications, and additional analytical testing are available upon request and subject to product availability.
    We support requirements from milligram and gram evaluation quantities to kilogram and multi-kilogram supply, depending on the molecule. Our services include custom peptide synthesis, specification-based sourcing, flexible packaging, international delivery, and temperature-controlled packaging where required.
    Research-grade products are supplied for laboratory research use only and are not intended for human or veterinary use. All products and services are subject to applicable regulations, product-specific review, and customer qualification.
    Zhaoke Biotech aims to be a reliable peptide API supplier and long-term sourcing partner for pharmaceutical companies, cosmetic manufacturers, laboratories, distributors, and other qualified professional customers.


  • Inquiry History
    105 Inquiries
    Country Product Purchase Quantity Date Posted
    Germany

    SS31

    1000 MG Oct 23, 2026
    United States

    SS-31

    10 MG Oct 16, 2026
    Canada

    Ss31

    20 MG Oct 16, 2026
    United States

    SS31

    1 G Oct 15, 2026
    Australia

    Ss-31

    50 MG Sep 28, 2026
    United States

    SS31

    30 MG Sep 20, 2026
    Australia

    Ss-31 (Elamipretide)

    1000 PCS Sep 16, 2026
    Philippines

    SS-31

    30 MG Sep 15, 2026
    United States

    SS-31

    50 MG Sep 8, 2026
    United States

    SS31

    10 MG Aug 28, 2026
    United States

    SS-31

    20 MG Aug 25, 2026
    United States

    SS31

    20 MG Aug 25, 2026
    Australia

    SS-31

    30 MG Aug 24, 2026
    United States

    Ss-31 Elamipretide

    1 PCS Aug 16, 2026
    Malaysia

    ss31

    20 MG Aug 12, 2026
    Canada

    Ss31

    1 G Jul 24, 2026
    Brazil

    SS-31 Lyophilized Powder

    0.1 G Jul 9, 2026
    Turkey

    SS-31 (Elamipretide MTP-131) CAS 99% White Powder

    100 G Jun 28, 2026
    India

    Elamipretide

    1 G Jun 23, 2026
    France

    Elamipretide

    3 G Jun 19, 2026
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